MirGeneDB 2.1
MirGeneDB ID

Sme-Mir-277-P6a

Family name MIR-277 (all species)
Seed UGCAUUA
Species Freshwater planarian (Schmidtea mediterranea)
MiRBase ID sme-mir-277b
Paralogues Sme-Mir-277-P6b  Sme-Mir-277-P7a  Sme-Mir-277-P7b 
Orthologues Aae-Mir-277  Bge-Mir-277  Bpl-Mir-277  Cbr-Mir-277-P6a  Cel-Mir-277  Cgi-Mir-277  Dan-Mir-277  Dma-Mir-277  Dme-Mir-277  Dmo-Mir-277  Dpu-Mir-277  Dsi-Mir-277  Dya-Mir-277  Efe-Mir-277  Esc-Mir-277  Hme-Mir-277  Isc-Mir-277  Lgi-Mir-277  Npo-Mir-277  Obi-Mir-277  Ovu-Mir-277  Tca-Mir-277 
Node of Origin (locus) S. mediterranea
Node of Origin (family) Protostomia
Genome context
(Sme_GCA_002600895.1_ASM260089v1_alt)		 NNSW01000140_dd_Smes_g4_140: 655258-655315 [-] UCSC Ensembl
Clustered miRNAs
(< 50kb from Mir-277-P6a)		 Mir-277-P7a NNSW01000140_dd_Smes_g4_140: 654964-655022 [-] UCSC Ensembl
Mir-277-P6a NNSW01000140_dd_Smes_g4_140: 655258-655315 [-] UCSC Ensembl
Precursor
(pre-Mir +30nt flank)
UUUAUUUUUUACAGAUCGGUUGUAUUGAUCUUGAUCAGAAAUGCAGCUUCAGAGAAAUCACUGUGAAAAUGCAUUAUCUGGCCAAGAAAAUGAAGCCUAAAACACAUCUAAGUAGACA
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Structure
        10            20        30         40        50       
UUUAUUUUUUACAGAUC----|   G    GA     AU    -      GCUUCAGAGAA 
                     GGUU UAUU  UCUUG  CAGA AAUGCA           A
                     CCGA GUAA  AGAAC  GUCU UUACGU           U
ACAGAUGAAUCUACACAAAAU^   A    A-     CG    A      AAAAGUGUCAC 
      110       100        90         80        70        60
Deep sequencing
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CommentThe mature read is shifted 3 nt 3' relative to the other paralogues resulting in a non-canonical Dicer cut. There are no 3p reads with the usual 2 nt Dicer offset.
3' NTU No
MotifsCNNC at 3p(+17)
Tissue expression
-   +
Se Se Se Se Se Se Se Se Se Se Se Se Ne Wh Wh Wh
Star sequence

Sme-Mir-277-P6a_5p*
mirBase accessionMIMAT0004008
Sequence 
0- UUGAUCAGAAAUGCAGCUUCA -21
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Mature sequence

Sme-Mir-277-P6a_3p
mirBase accessionMIMAT0004009
Sequence 
38- AUGCAUUAUCUGGCCAAGAA -58
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