MirGeneDB 3.0

MirGeneDB ID

Egr-Mir-2-o136

Family name MIR-2 (all species)
Seed CACAGCC
Species Hydatid worm (Echinococcus granulosus)
MiRBase ID egr-mir-2c
Paralogues Egr-Mir-2-o137  Egr-Mir-2-o138 
Orthologues Gsp-Mir-2  Ple-Mir-2 
Node of Origin (locus) E. granulosus
Node of Origin (family) Protostomia
Genome context
(GCA_000524195.1_ASM52419v1_Egranulosus)
APAU02000027.1: 925661-925716 [+] UCSC Ensembl
Clustered miRNAs
(< 50kb from Mir-2-o136)
Mir-71 APAU02000027.1: 925561-925620 [+] UCSC Ensembl
Mir-2-o136 APAU02000027.1: 925661-925716 [+] UCSC Ensembl
Mir-2-o137 APAU02000027.1: 925765-925820 [+] UCSC Ensembl
Precursor
(pre-Mir +30nt flank)
UUUGACCAUCCCGAUUACGGGCGUUGUUCGUCGUCAACAUUGCCUGUAGACACGGGUUGCGAUGUCACAGCCAAUAUUGAUGAACGAGUGGCGUCUUCUACCGUCGGUUUUUUUGC
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Structure
        10          20        30         40        50       
UUUGACCAUCCCGAUUAC--      UG    -|      C    C    A    CGGG 
                    GGGCGU  UUCG UCGUCAA AUUG CUGU GACA    U
                    UCUGCG  GAGC AGUAGUU UAAC GACA CUGU    U
CGUUUUUUUGGCUGCCAUCU      GU    A^      A    C    -    AGCG 
    110       100        90        80        70         60
Deep sequencing
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CommentIt is not clear either from phylogenetic or syntenic information how many Mir-2 genes were present in the last common ancestor of protostomes and how the multiple paralogues in lophotrochozoans relate to the four Mir-2 genes in arthropods. Thus all lophotrochozoan genes aside from Mir-2-P12 are classified as orphans pending further data and analysis.
3' NTU No
MotifsCNNC at 3p(+17)
Tissue expression
 +
Eg Eg Ev Ev Ad Fe Fe Hy Hy Hy Li Li Li Mi Mi Mi Po Po Po Po Po Po Po Pr Pr Pr Sm
Star sequence

Egr-Mir-2-o136_5p*

mirBase accessionMIMAT0020231
Sequence
0- UCGUCAACAUUGCCUGUAGACA -22
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Mature sequence

Egr-Mir-2-o136_3p

mirBase accessionMIMAT0020232
Sequence
34- UCACAGCCAAUAUUGAUGAACG -56
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