MirGeneDB 3.0

MirGeneDB ID

Egr-Mir-2-o137

Family name MIR-2 (all species)
Seed AUCACAG
Species Hydatid worm (Echinococcus granulosus)
MiRBase ID egr-mir-2b
Paralogues Egr-Mir-2-o136  Egr-Mir-2-o138 
Orthologues Gsp-Mir-2  Ple-Mir-2 
Node of Origin (locus) E. granulosus
Node of Origin (family) Protostomia
Genome context
(GCA_000524195.1_ASM52419v1_Egranulosus)
APAU02000027.1: 925765-925820 [+] UCSC Ensembl
Clustered miRNAs
(< 50kb from Mir-2-o137)
Mir-71 APAU02000027.1: 925561-925620 [+] UCSC Ensembl
Mir-2-o136 APAU02000027.1: 925661-925716 [+] UCSC Ensembl
Mir-2-o137 APAU02000027.1: 925765-925820 [+] UCSC Ensembl
Precursor
(pre-Mir +30nt flank)
CGGUUUUUUUGCUCUUUUGCUGUCAGUCGGUGUCCCAAGGGUGGUGAUCUACUCAGUGGGAGUAUCACAGCCCUGCUUGGGACACAUGCUGGCAGCUCGAACGACCGAAUUUCACC
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Structure
        10          20        30           40        50       
CGGUUUUUUUGCUCUUUU--         CG        ---|    G    UC    CAG 
                    GCUGUCAGU  GUGUCCCA   AGGGU GUGA  UACU   \
                    CGACGGUCG  CACAGGGU   UCCCG CACU  AUGA   U
CCACUUUAAGCCAGCAAGCU         UA        UCG^    A    --    GGG 
    110       100        90        80        70          60
Deep sequencing
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CommentIt is not clear either from phylogenetic or syntenic information how many Mir-2 genes were present in the last common ancestor of protostomes and how the multiple paralogues in lophotrochozoans relate to the four Mir-2 genes in arthropods. Thus all lophotrochozoan genes aside from Mir-2-P12 are classified as orphans pending further data and analysis.
3' NTU No
MotifsCNNC at 3p(+17)
Tissue expression
 +
Er Er Sr Sr Sr Sr Sr Sr Sr Sr Sr Sr Sr Sr Sr Sr Sr Sr Sr Sr Sr Sr Sr Sr Sr Sr Sr
Star sequence

Egr-Mir-2-o137_5p*

mirBase accessionMIMAT0037420
Sequence
0- UGUCCCAAGGGUGGUGAUCUACU -23
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Mature sequence

Egr-Mir-2-o137_3p

mirBase accessionMIMAT0020230
Sequence
32- UAUCACAGCCCUGCUUGGGACACA -56
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