MirGeneDB 3.0

MirGeneDB ID

Npo-Mir-2-o45

Family name MIR-2 (all species)
Seed CACAGCC
Species Chambered Nautilus (Nautilus pompilius)
MiRBase ID
Paralogues Npo-Mir-2-o47  Npo-Mir-2-o48a  Npo-Mir-2-o48b  Npo-Mir-2-o49  Npo-Mir-2-P12 
Orthologues Esc-Mir-2-o45-v1  Esc-Mir-2-o45-v2  Gsp-Mir-2  Obi-Mir-2-o45-v1  Obi-Mir-2-o45-v2  Ovu-Mir-2-o45-v1  Ovu-Mir-2-o45-v2  Ple-Mir-2 
Node of Origin (locus) Cephalopoda
Node of Origin (family) Protostomia
Genome context
(GCA_018389105_NPO)
JACATO010000013.1: 409573-409634 [+] Ensembl
Precursor
(pre-Mir +30nt flank)
GUGUUGCAGAGAGGUUUGCUGUCUACACGGGCGUCAAUGCUGGAUGUAAUAGUAUUUAGUGGAGAACCUAUCACAGCCAGCUUUGAUGAGCCAUGUUCACUGGCAAGUUCAACCACGAAGAA
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Structure
        10         20         30         40        50          
GUGUUGCAGAGAGGUUU-   -  CU   C  G-|     U     A   A   GUAUUUAG 
                  GCU GU  ACA GG  CGUCAA GCUGG UGU AUA        \
                  CGG CA  UGU CC  GUAGUU CGACC ACA UAU        U
AAGAAGCACCAACUUGAA   U  CU   A  GA^     U     G   C   CCAAGAGG 
120       110       100        90        80        70
Deep sequencing
CommentIt is not clear either from phylogenetic or syntenic information how many Mir-2 genes were present in the last common ancestor of protostomes and how the multiple paralogues in lophotrochozoans relate to the four Mir-2 genes in arthropods. Thus all lophotrochozoan genes aside from Mir-2-P12 are classified as orphans pending further data and analysis.
3' NTU Unknown
MotifsUG at 5p(-14), CNNC at 3p(+17)
Star sequence

Npo-Mir-2-o45_5p* (predicted)

mirBase accessionNone
Sequence
0- GCGUCAAUGCUGGAUGUAAUA -21
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Mature sequence

Npo-Mir-2-o45_3p (predicted)

mirBase accessionNone
Sequence
40- UCACAGCCAGCUUUGAUGAGCC -62
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