MirGeneDB 3.0

MirGeneDB ID

Npo-Mir-2-o48a

Family name MIR-2 (all species)
Seed AUCACAG
Species Chambered Nautilus (Nautilus pompilius)
MiRBase ID
Paralogues Npo-Mir-2-o45  Npo-Mir-2-o47  Npo-Mir-2-o48b  Npo-Mir-2-o49  Npo-Mir-2-P12 
Orthologues Esc-Mir-2-o48-v1  Esc-Mir-2-o48-v2  Gsp-Mir-2  Obi-Mir-2-o48-v1  Obi-Mir-2-o48-v2  Ovu-Mir-2-o48-v1  Ovu-Mir-2-o48-v2  Ple-Mir-2 
Node of Origin (locus) N. pompilius
Node of Origin (family) Protostomia
Genome context
(GCA_018389105_NPO)
JACATO010000013.1: 410153-410212 [+] Ensembl
Precursor
(pre-Mir +30nt flank)
CUGGAAGGGAAAAGUUGUUGCUGGAUUGAGGGCAUCAAAGUGGUGGUGAAAUGUUACCGCCUGUCAUAUCACAGCCAACUUUGAUGAGCUUUGAUUCGGUGCUGCUCGUCUACAGGAACU
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Structure
        10         20        30         40         50         
CUGGAAGGGAAAAGUUGUU-       UG   G-        -|   G    A   UUACC 
                    GCUGGAU  AGG  CAUCAAAG UGGU GUGA AUG     \
                    UGGCUUA  UUC  GUAGUUUC ACCG CACU UAC     G
UCAAGGACAUCUGCUCGUCG       GU   GA        A^   A    A   UGUCC 
.       110       100        90        80        70        60
Deep sequencing
CommentIt is not clear either from phylogenetic or syntenic information how many Mir-2 genes were present in the last common ancestor of protostomes and how the multiple paralogues in lophotrochozoans relate to the four Mir-2 genes in arthropods. Thus all lophotrochozoan genes aside from Mir-2-P12 are classified as orphans pending further data and analysis.
3' NTU Unknown
MotifsCNNC at 3p(+17)
Star sequence

Npo-Mir-2-o48a_5p* (predicted)

mirBase accessionNone
Sequence
0- GGCAUCAAAGUGGUGGUGAAAUG -23
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Mature sequence

Npo-Mir-2-o48a_3p (predicted)

mirBase accessionNone
Sequence
36- UAUCACAGCCAACUUUGAUGAGCU -60
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