Mir-92-o72

MirGeneDB ID

Cin-Mir-92-o72

Family name

MIR-92 (all species)

Seed

AUUGCAC

Species

Sea Squirt (Ciona intestinalis)

MiRBase ID

cin-mir-92a

Paralogues

Cin-Mir-92-o69 Cin-Mir-92-o70 Cin-Mir-92-o71 Cin-Mir-92-o73 Cin-Mir-92-o74 Cin-Mir-92-o75 Cin-Mir-92-o76 Cin-Mir-92-o77 Cin-Mir-92-o78

Orthologues

Asu-Mir-92 Cel-Mir-92 Esc-Mir-92 Gsp-Mir-92 Hmi-Mir-92 Isc-Mir-92 Obi-Mir-92 Sme-Mir-92

Node of Origin (locus)

C. intestinalis

Node of Origin (family)

Bilateria

Genome context
(ci3)

3: 884650-884701 [+] UCSC Ensembl

Clustered miRNAs
(< 50kb from Mir-92-o72)

Mir-92-o72 3: 884650-884701 [+] UCSC Ensembl
Mir-92-o73 3: 884985-885041 [+] UCSC Ensembl
Mir-92-o74 3: 885439-885494 [+] UCSC Ensembl

Precursor
(pre-Mir +30nt flank)

UUUAGUGAAGUUUGAUUAUAUAUUACUCGACGGCUGGUACAAGAGCACGAUCGAUUAGGAUAUUGCACUUGUCCCGGUCUUAGGGUGGUAUAAAAAAGCAACUUAUCACAUU

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Structure

        10          20        30        40        50     
UUUAGUGAAGUUUGAUUA--|         GAC      U     A   CG   GA 
                    UAUAUUACUC   GGCUGG ACAAG GCA  AUC  U
                    AUAUGGUGGG   CUGGCC UGUUC CGU  UAG  U
UUACACUAUUCAACGAAAAA^         AUU      C     A   UA   GA 
110       100        90        80        70        60

Deep sequencing

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Comment

It is not clear either from phylogenetic or syntenic information how many Mir-92 genes were present in the last common ancestor of bilaterians and how the vertebrate Mir-92s relate to the invertebrate Mir-92s and thus these multiple paralogues in invertebrates are classified here as orphans pending new data.

3' NTU

Motifs

CNNC at 3p(+17)

Tissue expression

C-	C-	C-	C-	C-	C-	C-	C-	C-	C-	Ga	La	La

Star sequence

Cin-Mir-92-o72_5p*

mirBase accession

MIMAT0015253

Sequence

0- CGGCUGGUACAAGAGCACGAUC -22

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Mature sequence

Cin-Mir-92-o72_3p

mirBase accession

MIMAT0006096

Sequence

30- UAUUGCACUUGUCCCGGUCUUA -52

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