Mir-376-P2

MirGeneDB ID

Hsa-Mir-376-P2

Family name

MIR-376 (all species)

Seed

ACAUAGA

Species

Human (Homo sapiens)

MiRBase ID

hsa-mir-376c

Paralogues

Hsa-Mir-376-P1 Hsa-Mir-376-P3 Hsa-Mir-376-P4 Hsa-Mir-376-P5

Orthologues

Bta-Mir-376-P2 Cfa-Mir-376-P2 Cja-Mir-376-P2 Cpo-Mir-376-P2 Dno-Mir-376-P2 Eca-Mir-376-P2 Ete-Mir-376-P2 Laf-Mir-376-P2 Mml-Mir-376-P2 Mmr-Mir-376-P2 Mmu-Mir-376-P2 Ocu-Mir-376-P2 Pab-Mir-376-P2 Rno-Mir-376-P2

Node of Origin (locus)

Eutheria

Node of Origin (family)

Eutheria

Genome context
(hg38)

chr14: 101039695-101039752 [+] UCSC Ensembl

Clustered miRNAs
(< 50kb from Mir-376-P2)

Mir-154-P1 chr14: 101022071-101022129 [+] UCSC Ensembl
Mir-154-P2-v2 chr14: 101023339-101023396 [+] UCSC Ensembl
Mir-154-P2-v1 chr14: 101023340-101023395 [+] UCSC Ensembl
Mir-154-P3-v1 chr14: 101023799-101023853 [+] UCSC Ensembl
Mir-154-P3-v2 chr14: 101023800-101023852 [+] UCSC Ensembl
Mir-154-P4 chr14: 101025020-101025076 [+] UCSC Ensembl
Mir-154-P5 chr14: 101025585-101025640 [+] UCSC Ensembl
Mir-154-P6a-v1 chr14: 101025747-101025802 [+] UCSC Ensembl
Mir-154-P6a-v2 chr14: 101025747-101025802 [+] UCSC Ensembl
Mir-154-P7 chr14: 101026035-101026092 [+] UCSC Ensembl
Mir-154-P8a chr14: 101026796-101026855 [+] UCSC Ensembl
Mir-154-P8b chr14: 101027113-101027172 [+] UCSC Ensembl
Mir-154-P9 chr14: 101029648-101029703 [+] UCSC Ensembl
Mir-154-P10 chr14: 101030064-101030120 [+] UCSC Ensembl
Mir-154-P11 chr14: 101031997-101032054 [+] UCSC Ensembl
Mir-154-P12 chr14: 101033768-101033825 [+] UCSC Ensembl
Mir-376-P2 chr14: 101039695-101039752 [+] UCSC Ensembl
Mir-376-P3 chr14: 101040081-101040138 [+] UCSC Ensembl
Mir-154-P14 chr14: 101040234-101040289 [+] UCSC Ensembl
Mir-376-P4 chr14: 101040460-101040517 [+] UCSC Ensembl
Mir-376-P5 chr14: 101040788-101040845 [+] UCSC Ensembl
Mir-154-P16a chr14: 101042991-101043050 [+] UCSC Ensembl
Mir-154-P16b chr14: 101044212-101044271 [+] UCSC Ensembl
Mir-154-P17 chr14: 101045927-101045989 [+] UCSC Ensembl
Mir-154-P18 chr14: 101046469-101046526 [+] UCSC Ensembl
Mir-154-P19 chr14: 101047329-101047392 [+] UCSC Ensembl
Mir-154-P20 chr14: 101047911-101047969 [+] UCSC Ensembl
Mir-544 chr14: 101048676-101048732 [+] UCSC Ensembl
Mir-154-P21 chr14: 101049572-101049631 [+] UCSC Ensembl
Mir-154-P23 chr14: 101052458-101052515 [+] UCSC Ensembl
Mir-154-P24 chr14: 101054316-101054373 [+] UCSC Ensembl
Mir-134 chr14: 101054694-101054754 [+] UCSC Ensembl
Mir-154-P25 chr14: 101055427-101055485 [+] UCSC Ensembl
Mir-154-P6b chr14: 101056233-101056289 [+] UCSC Ensembl
Mir-154-P26 chr14: 101059769-101059826 [+] UCSC Ensembl
Mir-154-P28-v2 chr14: 101060595-101060650 [+] UCSC Ensembl
Mir-154-P28-v1 chr14: 101060596-101060649 [+] UCSC Ensembl
Mir-154-P29 chr14: 101062056-101062115 [+] UCSC Ensembl
Mir-541 chr14: 101064504-101064569 [+] UCSC Ensembl
Mir-154-P30 chr14: 101065314-101065367 [+] UCSC Ensembl
Mir-154-P31 chr14: 101065465-101065519 [+] UCSC Ensembl
Mir-154-P32 chr14: 101065606-101065661 [+] UCSC Ensembl
Mir-154-P33 chr14: 101065925-101065981 [+] UCSC Ensembl
Mir-154-P34 chr14: 101066731-101066786 [+] UCSC Ensembl

Precursor
(pre-Mir +30nt flank)

AGGACUCAAUCCUUCUUUGGUAUUUAAAAGGUGGAUAUUCCUUCUAUGUUUAUGUUAUUUAUGGUUAAACAUAGAGGAAAUUCCACGUUUUCAGUAUCAAAUGCUGCUUGGAAACAUU

Get precursor sequence

Structure

        10          20        30        40        50         
AGGACUCAAUCCUUCUU--|      U    G     UA     U         UGUUAU 
                   UGGUAUU AAAA GUGGA  UUCCU CUAUGUUUA      \
                   ACUAUGA UUUU CACCU  AAGGA GAUACAAAU      U
UUACAAAGGUUCGUCGUAA^      C    G     UA     -         UGGUAU 
      110       100        90        80         70        60

Deep sequencing

Go to detailed chart

3' NTU

Motifs

CNNC at 3p(+17), UGUG in loop

Tissue expression

Dc	Dc	Dr	Dr	Xp	Xp	Bl	Br	Br	Ce	Ce	Co	Fo	He	Ki	Le	Li	Li	Lu	Pa	Pl	Pl	Sk	Sk	Sk	Sm	Sp	Sp	St	Te	Th	Ut

Star sequence

Hsa-Mir-376-P2_5p*

mirBase accession

MIMAT0022861

Sequence

0- GUGGAUAUUCCUUCUAUGUUUA -22

Get sequence

Proposed targets

TargetScanVert: hsa-miR-376c-5p
miRDB: MIMAT0022861

Mature sequence

Hsa-Mir-376-P2_3p

mirBase accession

MIMAT0000720

Sequence

37- AACAUAGAGGAAAUUCCACGU -58

Get sequence

Proposed targets

microrna.org: MIMAT0000720
TargetScanVert: hsa-miR-376c-3p
miRDB: MIMAT0000720