MirGeneDB 3.0
MirGeneDB ID

Sme-Let-7-P20b

Family name LET-7 (all species)
Seed GAGGUAG
Species Freshwater planarian (Schmidtea mediterranea)
MiRBase ID sme-let-7b
Paralogues Sme-Let-7-P19a  Sme-Let-7-P19b  Sme-Let-7-P20a  Sme-Let-7-P21  Sme-Let-7-P22 
Orthologues Aae-Let-7  Aga-Let-7  Agr-Let-7  Bge-Let-7  Bko-Let-7  Bpl-Let-7  Cte-Let-7  Dan-Let-7  Dlo-Let-7  Dma-Let-7  Dme-Let-7  Dmo-Let-7  Dpu-Let-7  Dsi-Let-7  Dya-Let-7  Eba-Let-7  Egr-Let-7  Esc-Let-7  Gpa-Let-7  Gsa-Let-7  Gsp-Let-7  Hme-Let-7  Hmi-Let-7  Hru-Let-7  Isc-Let-7  Lan-Let-7  Lgi-Let-7  Lhy-Let-7  Llo-Let-7  Mgi-Let-7  Mom-Let-7  Npo-Let-7  Obi-Let-7  Ofu-Let-7  Ovu-Let-7  Pau-Let-7  Pca-Let-7  Pcr-Let-7  Pdu-Let-7  Pfl-Let-7  Ple-Let-7  Pmi-Let-7  Pve-Let-7  Rph-Let-7  Sko-Let-7  Sma-Let-7  Sne-Let-7  Snu-Let-7  Spu-Let-7  Sro-Let-7  Tca-Let-7  Tur-Let-7  War-Let-7  Xbo-Let-7 
Node of Origin (locus) S. mediterranea
Node of Origin (family) Bilateria
Genome context
(Sme_GCA_002600895.1_ASM260089v1_alt)		 NNSW01000045_dd_Smes_g4_45: 2341596-2341651 [-] UCSC Ensembl
Clustered miRNAs
(< 50kb from Let-7-P20b)		 Let-7-P20b NNSW01000045_dd_Smes_g4_45: 2341596-2341651 [-] UCSC Ensembl
Mir-36-P19 NNSW01000045_dd_Smes_g4_45: 2342053-2342111 [-] UCSC Ensembl
Precursor
(pre-Mir +30nt flank)
UACGGGAAUCCGUUAAGUAACAUUAACAAUUGAGGUAGAUUGUUGGAUGACUUAAUUUUAAAGCCAUUCAACUAUCUGUCUUCUCUUGUUAAAUUACAUAUCAUCAUCAAGAAGGA
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Structure
        10        20          30         40        50       
UACGGGAAUCCGUUAAGUAACA--       UU    -|    U        A  UAAU 
                        UUAACAA  GAGG UAGAU GUUGGAUG CU    \
                        AAUUGUU  CUUC GUCUA CAACUUAC GA    U
AGGAAGAACUACUACUAUACAUUA       CU    U^    U        C  AAUU 
    110       100        90        80        70        60
Deep sequencing
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3' NTU No
MotifsCNNC at 3p(+17)
Tissue expression
-   +
Ag Ag Di Gf Ne Ph Se Se Se Se Se Se Se Se Se Se Se Wh Wh Wh
Mature sequence

Sme-Let-7-P20b_5p
mirBase accessionMIMAT0003953
Sequence 
0- UGAGGUAGAUUGUUGGAUGACU -22
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Star sequence

Sme-Let-7-P20b_3p*
mirBase accessionMIMAT0003954
Sequence 
33- CCAUUCAACUAUCUGUCUUCUCU -56
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