Let-7-P2b4

MirGeneDB ID

Aca-Let-7-P2b4

Family name

LET-7 (all species)

Seed

GAGGUAG

Species

Green anole lizard (Anolis carolinensis)

MiRBase ID

Paralogues

Aca-Let-7-P1b Aca-Let-7-P1c Aca-Let-7-P1d Aca-Let-7-P2a1 Aca-Let-7-P2a2 Aca-Let-7-P2a3 Aca-Let-7-P2a4 Aca-Let-7-P2b1 Aca-Let-7-P2b2 Aca-Let-7-P2b3 Aca-Let-7-P2c1 Aca-Let-7-P2c2 Aca-Let-7-P2c3

Orthologues

Aae-Let-7 Aga-Let-7 Agr-Let-7 Ami-Let-7-P2b4 Bge-Let-7 Bko-Let-7 Bpl-Let-7 Cli-Let-7-P2b4 Cmi-Let-7-P2b4 Cpi-Let-7-P2b4 Cte-Let-7 Dan-Let-7 Dlo-Let-7 Dma-Let-7 Dme-Let-7 Dmo-Let-7 Dpu-Let-7 Dre-Let-7-P2b4a Dre-Let-7-P2b4b Dsi-Let-7 Dya-Let-7 Eba-Let-7 Egr-Let-7 Esc-Let-7 Gga-Let-7-P2b4 Gja-Let-7-P2b4 Gmo-Let-7-P2b4a Gmo-Let-7-P2b4b Gpa-Let-7 Gsa-Let-7 Gsp-Let-7 Hme-Let-7 Hmi-Let-7 Hru-Let-7 Isc-Let-7 Lan-Let-7 Lch-Let-7-P2b4 Lgi-Let-7 Lhy-Let-7 Llo-Let-7 Loc-Let-7-P2b4 Mal-Let-7-P2b4a Mal-Let-7-P2b4b Mgi-Let-7 Mom-Let-7 Mun-Let-7-P2b4 Npo-Let-7 Oan-Let-7-P2b4 Obi-Let-7 Ofu-Let-7 Ovu-Let-7 Pau-Let-7 Pbv-Let-7-P2b4 Pca-Let-7 Pcr-Let-7 Pdu-Let-7 Pfl-Let-7 Ple-Let-7 Pmi-Let-7 Pve-Let-7 Rph-Let-7 Sko-Let-7 Sma-Let-7 Sne-Let-7 Snu-Let-7 Spt-Let-7-P2b4 Spu-Let-7 Sro-Let-7 Tca-Let-7 Tgu-Let-7-P2b4 Tni-Let-7-P2b4a Tni-Let-7-P2b4b Tur-Let-7 War-Let-7 Xbo-Let-7

Node of Origin (locus)

Gnathostomata

Node of Origin (family)

Bilateria

Genome context
(anoCar2)

4: 123683315-123683391 [-] UCSC Ensembl

Precursor
(pre-Mir +30nt flank)

AUAUGAAGCCUCUAUCUUGCUUUGUGGAGGUGAGGUAGUAGGUUGUAUAGUUUGUGGGAGGGAUUACAUCCCAUUUCAGGUGAUAACUAUACAGUCUAUUGCCUUCCUUAAGGAGCAACAAAUCUGGCUUAGGAGCA

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Structure

        10           20        30        40        50        60        
AUAUGAAGCCUCUAUCU---|     GUG    U          GU         UGUGGGAGGGAUUAC 
                    UGCUUU   GAGG GAGGUAGUAG  UGUAUAGUU               A
                    ACGAGG   UUCC UUCCGUUAUC  ACAUAUCAA               U
ACGAGGAUUCGGUCUAAACA^     AA-    -          UG         UAGUGGACUUUACCC 
     130       120       110         100        90        80        70

Deep sequencing

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Comment

Although all Let-7-P13s have a templated "T" all other vertebrate Let-7-P4 through P14s are Group 2 miRNAs and where studied all 3' terminal "U"s are post-transcriptionally added to the transcript and thus P13 is also considered a Group 2 miRNA.

3' NTU

Yes

Motifs

UGUG in loop

Tissue expression

Sk	Ta	Ta	To	Wh

Mature sequence

Aca-Let-7-P2b4_5p

mirBase accession

None

Sequence

0- UGAGGUAGUAGGUUGUAUAGUU -22

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Star sequence

Aca-Let-7-P2b4_3p*

mirBase accession

None

Sequence

56- CUAUACAGUCUAUUGCCUUCC -77

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