MirGeneDB 3.0

MirGeneDB ID

Gmo-Let-7-P2b4b

Family name LET-7 (all species)
Seed GAGGUAG
Species Cod (Gadus morhua)
MiRBase ID gmo-let-7a-4
Paralogues Gmo-Let-7-P1b1  Gmo-Let-7-P1b2  Gmo-Let-7-P1c2  Gmo-Let-7-P1d1  Gmo-Let-7-P1d2  Gmo-Let-7-P2a1a  Gmo-Let-7-P2a2a  Gmo-Let-7-P2a3a  Gmo-Let-7-P2a3b  Gmo-Let-7-P2a4a  Gmo-Let-7-P2a4b  Gmo-Let-7-P2b1a  Gmo-Let-7-P2b2a  Gmo-Let-7-P2b3a  Gmo-Let-7-P2b3b  Gmo-Let-7-P2b4a  Gmo-Let-7-P2c2a  Gmo-Let-7-P2c2b  Gmo-Let-7-P2c3 
Orthologues Aae-Let-7  Aca-Let-7-P2b4  Aga-Let-7  Agr-Let-7  Ami-Let-7-P2b4  Bge-Let-7  Bko-Let-7  Bpl-Let-7  Cli-Let-7-P2b4  Cmi-Let-7-P2b4  Cpi-Let-7-P2b4  Cte-Let-7  Dan-Let-7  Dlo-Let-7  Dma-Let-7  Dme-Let-7  Dmo-Let-7  Dpu-Let-7  Dre-Let-7-P2b4a  Dre-Let-7-P2b4b  Dsi-Let-7  Dya-Let-7  Eba-Let-7  Egr-Let-7  Esc-Let-7  Gga-Let-7-P2b4  Gja-Let-7-P2b4  Gpa-Let-7  Gsa-Let-7  Gsp-Let-7  Hme-Let-7  Hmi-Let-7  Hru-Let-7  Isc-Let-7  Lan-Let-7  Lch-Let-7-P2b4  Lgi-Let-7  Lhy-Let-7  Llo-Let-7  Loc-Let-7-P2b4  Mal-Let-7-P2b4a  Mal-Let-7-P2b4b  Mgi-Let-7  Mom-Let-7  Mun-Let-7-P2b4  Npo-Let-7  Oan-Let-7-P2b4  Obi-Let-7  Ofu-Let-7  Ovu-Let-7  Pau-Let-7  Pbv-Let-7-P2b4  Pca-Let-7  Pcr-Let-7  Pdu-Let-7  Pfl-Let-7  Ple-Let-7  Pmi-Let-7  Pve-Let-7  Rph-Let-7  Sko-Let-7  Sma-Let-7  Sne-Let-7  Snu-Let-7  Spt-Let-7-P2b4  Spu-Let-7  Sro-Let-7  Tca-Let-7  Tgu-Let-7-P2b4  Tni-Let-7-P2b4a  Tni-Let-7-P2b4b  Tur-Let-7  War-Let-7  Xbo-Let-7 
Node of Origin (locus) Clupeocephala
Node of Origin (family) Bilateria
Genome context
(Gadus_morhua.gadMor1.dna.toplevel)
contig98176: 498-574 [-] UCSC Ensembl
Clustered miRNAs
(< 50kb from Let-7-P2b4b)
Let-7-P2b4b contig98176: 498-574 [-] UCSC Ensembl
Let-7-P2a4b contig98176: 705-775 [-] UCSC Ensembl
Precursor
(pre-Mir +30nt flank)
ACUUUUCUACUCGAGCUAGACCUUGCGAGGUGAGGUAGUAGGUUGUAUAGUUUGUGGGAUGGAUUGAAUCCUUAUUUUGGUGAUAACUAUACAGUCUAGUGCCUUUCUCGAGAGGUGUAAAGAAACGCUGGGAUGCU
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Structure
        10          20        30        40        50        60        
ACUUUUCUACUCGAGCU--|G    UG     U      G   GU         UGUGGGAUGGAUUGA 
                   A ACCU  CGAGG GAGGUA UAG  UGUAUAGUU               A
                   U UGGA  GCUCU UUCCGU AUC  ACAUAUCAA               U
UCGUAGGGUCGCAAAGAAA^G    GA     -      G   UG         UAGUGGUUUUAUUCC 
     130       120       110        100        90        80        70
Deep sequencing
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CommentAlthough there is a templated T at the 3' end of the 3p arm, the post-transcriptional addition of a terminal 3' U is supported by the conservation of Let7-P2 processing and the sequenced 3' DcRNA reads.
3' NTU Yes
MotifsUGUG in loop
Tissue expression
 +
Br Gi He In Li Sk Sp Wh
Mature sequence

Gmo-Let-7-P2b4b_5p

mirBase accessionMIMAT0044081
Sequence
0- UGAGGUAGUAGGUUGUAUAGUU -22
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Star sequence

Gmo-Let-7-P2b4b_3p*

mirBase accessionMIMAT0044084
Sequence
56- CUAUACAGUCUAGUGCCUUUC -77
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