MirGeneDB 3.0

MirGeneDB ID

Mmu-Mir-451

Family name MIR-451 (all species)
Seed AACCGUU
Species House mouse (Mus musculus)
MiRBase ID mmu-mir-451a
Paralogues
Orthologues Aca-Mir-451  Ami-Mir-451  Bta-Mir-451  Cfa-Mir-451  Cja-Mir-451  Cli-Mir-451  Cmi-Mir-451  Cpi-Mir-451  Cpo-Mir-451  Dno-Mir-451  Dre-Mir-451  Ebu-Mir-451  Eca-Mir-451  Ete-Mir-451  Gga-Mir-451  Gja-Mir-451  Gmo-Mir-451  Hsa-Mir-451  Laf-Mir-451  Lch-Mir-451  Loc-Mir-451  Mal-Mir-451  Mdo-Mir-451  Mml-Mir-451  Mmr-Mir-451  Mun-Mir-451  Neu-Mir-451  Oan-Mir-451  Ocu-Mir-451  Pab-Mir-451  Pma-Mir-451  Rno-Mir-451  Sha-Mir-451  Spt-Mir-451  Sto-Mir-451  Tgu-Mir-451  Tni-Mir-451  Xla-Mir-451-P1  Xla-Mir-451-P2  Xtr-Mir-451 
Node of Origin (locus) Vertebrata
Node of Origin (family) Vertebrata
Genome context
(mm10)
chr11: 78073186-78073227 [+] UCSC Ensembl
Clustered miRNAs
(< 50kb from Mir-451)
Mir-144-v1 chr11: 78073010-78073067 [+] UCSC Ensembl
Mir-144-v2 chr11: 78073010-78073067 [+] UCSC Ensembl
Mir-451 chr11: 78073186-78073227 [+] UCSC Ensembl
Precursor
(pre-Mir +30nt flank)
UGACAGCUGUGGCACUUGGGAAUGGCGAGGAAACCGUUACCAUUACUGAGUUUAGUAAUGGUAACGGUUCUCUUGCUGCUCCCACAAACUGUGCCAAGAAGA
Get precursor sequence
Structure
        10          20        30        40        50
UGACAGCUGUGGCACUU--|   AU      GA                 A 
                   GGGA  GGCGAG  AACCGUUACCAUUACUG G
                   CCCU  UCGUUC  UUGGCAAUGGUAAUGAU U
AGAAGAACCGUGUCAAACA^   CG      UC                 U 
100        90        80        70        60
Deep sequencing
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CommentAs a non-canonical (Group 4, Kim et al. 2016) miRNA there is no discrete 3p read and the 3' end of the mature miRNA is somewhat arbitrary.
3' NTU NA
MotifsUG at 5p(-14)
Tissue expression
 +
Br Br Ce Ce Em Em He Ki Li Lu Ov Pa Sk Sp Te
Mature sequence

Mmu-Mir-451_5p

mirBase accessionMIMAT0001632
Sequence
0- AAACCGUUACCAUUACUGAGUU -22
Get sequence
Proposed targets microrna.org: MIMAT0001632
TargetScanVert: mmu-miR-451a
miRDB: MIMAT0001632