MirGeneDB 3.0

MirGeneDB ID

Sma-Mir-2-o133

Family name MIR-2 (all species)
Seed GUGUUGA
Species Blood fluke (Schistosoma mansoni)
MiRBase ID sma-mir-2f
Paralogues Sma-Mir-2-o130  Sma-Mir-2-o131  Sma-Mir-2-o132  Sma-Mir-2-o134  Sma-Mir-2-o135 
Orthologues Gsp-Mir-2  Ple-Mir-2 
Node of Origin (locus) S. mansoni
Node of Origin (family) Protostomia
Genome context
(GCA_000237925.5_SM_V9_genomic)
HE601628.3: 9679871-9679943 [+] UCSC Ensembl
Clustered miRNAs
(< 50kb from Mir-2-o133)
Mir-71-o6 HE601628.3: 9679749-9679802 [+] UCSC Ensembl
Mir-2-o133 HE601628.3: 9679871-9679943 [+] UCSC Ensembl
Mir-2-o134 HE601628.3: 9679986-9680055 [+] UCSC Ensembl
Mir-2-o135 HE601628.3: 9680098-9680158 [+] UCSC Ensembl
Precursor
(pre-Mir +30nt flank)
GAGAAGGAUUCGUAAUGCUGCACGAUACCUGGUGUUGAUUCUGGCUGAGAUUGAGGCAGGAAAAUAAACAAUUGUUGCCUGUCACAGCCAAUAUUGAUACCCGGCGUUGGGCACUUGACUUCUAAGAUGUAAC
Get precursor sequence
Structure
        10          20        30        40        50        60      
GAGAAGGAUUCGUAAUGC--|  A   UA  U     UG  UC      A   UGAGGCAGGAAAAU 
                    UGC CGA  CC GGUGU  AU  UGGCUG GAU              \
                    ACG GUU  GG CCAUA  UA  ACCGAC CUG              A
CAAUGUAGAAUCUUCAGUUC^  G   GC  C     GU  UA      A   UCCGUUGUUAACAA 
 130       120       110       100        90        80        70
Deep sequencing
Go to detailed chart
CommentIt is not clear either from phylogenetic or syntenic information how many Mir-2 genes were present in the last common ancestor of protostomes and how the multiple paralogues in lophotrochozoans relate to the four Mir-2 genes in arthropods. Thus all lophotrochozoan genes aside from Mir-2-P12 are classified as orphans pending further data and analysis.
3' NTU Unknown
MotifsCNNC at 3p(+17)
Tissue expression
 +
Ad Ad Ad Ad Ad Ad Ad Ad Ad Ad Ad Ad Ad Ad Ad Ce Ce Ce Eg Eg Eg Eg Eg Eg Mi Mi Sc Sc Sc Sm Sm Sp Sp Sp
Mature sequence

Sma-Mir-2-o133_5p

mirBase accessionNone
Sequence
0- GGUGUUGAUUCUGGCUGAGAUU -22
Get sequence
Star sequence

Sma-Mir-2-o133_3p*

mirBase accessionMIMAT0033691
Sequence
51- UCACAGCCAAUAUUGAUACCCG -73
Get sequence