MirGeneDB 3.0

MirGeneDB ID

Sma-Mir-2-o134

Family name MIR-2 (all species)
Seed UCAUCCU
Species Blood fluke (Schistosoma mansoni)
MiRBase ID sma-mir-2d
Paralogues Sma-Mir-2-o130  Sma-Mir-2-o131  Sma-Mir-2-o132  Sma-Mir-2-o133  Sma-Mir-2-o135 
Orthologues Gsp-Mir-2  Ple-Mir-2 
Node of Origin (locus) S. mansoni
Node of Origin (family) Protostomia
Genome context
(GCA_000237925.5_SM_V9_genomic)
HE601628.3: 9679986-9680055 [+] UCSC Ensembl
Clustered miRNAs
(< 50kb from Mir-2-o134)
Mir-71-o6 HE601628.3: 9679749-9679802 [+] UCSC Ensembl
Mir-2-o133 HE601628.3: 9679871-9679943 [+] UCSC Ensembl
Mir-2-o134 HE601628.3: 9679986-9680055 [+] UCSC Ensembl
Mir-2-o135 HE601628.3: 9680098-9680158 [+] UCSC Ensembl
Precursor
(pre-Mir +30nt flank)
UGACUUCUAAGAUGUAACCGCGACCAGUUCGUCAUCCUUGGAUUGUGAUUUUCCGAAAUAAAAUUUUAUGAAUAGAAUAUCACAGUCCUGCUUAGGUGACGAAUUUCGCUGGUUAACCUUCGCAAACCAG
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Structure
        10          20        30           40        50        60    
UGACUUCUAAGAUGUAA-  -    CC           CUU---|         UUUCCGAAAUAAAA 
                  CC GCGA  AGUUCGUCAUC      GGAUUGUGAU              \
                  GG CGCU  UUAAGCAGUGG      CCUGACACUA              U
GACCAAACGCUUCCAAUU  U    --           AUUCGU^         UAAGAUAAGUAUUU 
.       120       110         100        90        80        70
Deep sequencing
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CommentIt is not clear either from phylogenetic or syntenic information how many Mir-2 genes were present in the last common ancestor of protostomes and how the multiple paralogues in lophotrochozoans relate to the four Mir-2 genes in arthropods. Thus all lophotrochozoan genes aside from Mir-2-P12 are classified as orphans pending further data and analysis.
3' NTU Unknown
MotifsCNNC at 3p(+17)
Tissue expression
 +
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Mature sequence

Sma-Mir-2-o134_5p

mirBase accessionMIMAT0032135
Sequence
0- GUCAUCCUUGGAUUGUGAUUUU -22
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Star sequence

Sma-Mir-2-o134_3p*

mirBase accessionMIMAT0025035
Sequence
47- UAUCACAGUCCUGCUUAGGUGAC -70
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