MirGeneDB 3.0

MirGeneDB ID

Sme-Mir-2-o129

Family name MIR-2 (all species)
Seed CACAGCC
Species Freshwater planarian (Schmidtea mediterranea)
MiRBase ID sme-mir-2b
Paralogues Sme-Mir-2-o122a  Sme-Mir-2-o122b  Sme-Mir-2-o123  Sme-Mir-2-o124  Sme-Mir-2-o125  Sme-Mir-2-o126  Sme-Mir-2-o127  Sme-Mir-2-o128 
Orthologues Gsp-Mir-2  Ple-Mir-2 
Node of Origin (locus) S. mediterranea
Node of Origin (family) Protostomia
Genome context
(Sme_GCA_002600895.1_ASM260089v1_alt)
NNSW01000014_dd_Smes_g4_14: 3096425-3096480 [+] UCSC Ensembl
Precursor
(pre-Mir +30nt flank)
GUUAGUUGAAUAUUUUUAUGGUUAUUGCUUUCAUCAUUGUUGGUUGUCAGUUAUUGUAUUCAAUAUCACAGCCAAUUUUGAUGAGAUGAGAUAGCUUUCAGUCGUCACAAUUUUUC
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Structure
        10         20         30        40        50       
GUUAGUUGAAUAUUUUUAU-       GC-|       UU         CAGUUAUUG 
                    GGUUAUU   UUUCAUCA  GUUGGUUGU         U
                    UCGAUAG   AGAGUAGU  UAACCGACA         A
CUUUUUAACACUGCUGACUU       AGU^       UU         CUAUAACUU 
    110       100        90        80        70        60
Deep sequencing
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CommentIt is not clear either from phylogenetic or syntenic information how many Mir-2 genes were present in the last common ancestor of protostomes and how the multiple paralogues in lophotrochozoans relate to the four Mir-2 genes in arthropods. Thus all lophotrochozoan genes aside from Mir-2-P12 are classified as orphans pending further data and analysis.
3' NTU Yes
MotifsCNNC at 3p(+17)
Tissue expression
 +
Ag Ag Di Gf Ne Ph Se Se Se Se Se Se Se Se Se Se Se Wh Wh Wh
Star sequence

Sme-Mir-2-o129_5p*

mirBase accessionMIMAT0003965
Sequence
0- UCAUCAUUGUUGGUUGUCAGU -21
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Mature sequence

Sme-Mir-2-o129_3p

mirBase accessionMIMAT0003966
Sequence
35- UCACAGCCAAUUUUGAUGAGA -56
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