MirGeneDB 3.0
MirGeneDB ID

Sme-Mir-2-o122a

Family name MIR-2 (all species)
Seed AUCACAG
Species Freshwater planarian (Schmidtea mediterranea)
MiRBase ID sme-mir-2a-1
Paralogues Sme-Mir-2-o122b  Sme-Mir-2-o123  Sme-Mir-2-o124  Sme-Mir-2-o125  Sme-Mir-2-o126  Sme-Mir-2-o127  Sme-Mir-2-o128  Sme-Mir-2-o129 
Orthologues Gsp-Mir-2  Ple-Mir-2 
Node of Origin (locus) S. mediterranea
Node of Origin (family) Protostomia
Genome context
(Sme_GCA_002600895.1_ASM260089v1_alt)		 NNSW01000035_dd_Smes_g4_35: 577882-577946 [+] UCSC Ensembl
Clustered miRNAs
(< 50kb from Mir-2-o122a)		 Mir-71-o1a NNSW01000035_dd_Smes_g4_35: 577784-577841 [+] UCSC Ensembl
Mir-2-o122a NNSW01000035_dd_Smes_g4_35: 577882-577946 [+] UCSC Ensembl
Precursor
(pre-Mir +30nt flank)
AACGAUCGUAAUAUCAGUUCAUUUAUGUGAGUUCCAGUGUGCUAUGAUGUAUAUUUCUAAAAAUUUUCUAUAUAUCACAGCCCCGCUUGGAACGCUAAUUAAUGAAUAAUCAUUCAUAAUAUUUA
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Structure
        10          20        30         40         50        60 
AACGAUCGUAAUAUCAG--      U  GUGA     -    U-|  A       UAUUUCUAA 
                   UUCAUU AU    GUUCC AGUG  GCU UGAUGUA         \
                   AAGUAA UA    CAAGG UCGC  CGA ACUAUAU         A
AUUUAUAAUACUUACUAAU      U  AUCG     U    CC^  C       AUCUUUUAA 
   120       110       100        90        80        70
Deep sequencing
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CommentIt is not clear either from phylogenetic or syntenic information how many Mir-2 genes were present in the last common ancestor of protostomes and how the multiple paralogues in lophotrochozoans relate to the four Mir-2 genes in arthropods. Thus all lophotrochozoan genes aside from Mir-2-P12 are classified as orphans pending further data and analysis.
3' NTU No
MotifsNo
Tissue expression
-   +
Ag Ag Di Gf Ne Ph Se Se Se Se Se Se Se Se Se Se Se Wh Wh Wh
Star sequence

Sme-Mir-2-o122a_5p*
mirBase accessionMIMAT0003964
Sequence 
0- GUUCCAGUGUGCUAUGAUGUA -21
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Mature sequence

Sme-Mir-2-o122a_3p
mirBase accessionMIMAT0003963
Sequence 
42- UAUCACAGCCCCGCUUGGAACGC -65
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