MirGeneDB 3.0

MirGeneDB ID

Sme-Mir-2-o124

Family name MIR-2 (all species)
Seed CUCCAAA
Species Freshwater planarian (Schmidtea mediterranea)
MiRBase ID sme-mir-752
Paralogues Sme-Mir-2-o122a  Sme-Mir-2-o122b  Sme-Mir-2-o123  Sme-Mir-2-o125  Sme-Mir-2-o126  Sme-Mir-2-o127  Sme-Mir-2-o128  Sme-Mir-2-o129 
Orthologues Gsp-Mir-2  Ple-Mir-2 
Node of Origin (locus) S. mediterranea
Node of Origin (family) Protostomia
Genome context
(Sme_GCA_002600895.1_ASM260089v1_alt)
NNSW01000131_dd_Smes_g4_131: 1191422-1191481 [+] UCSC Ensembl
Clustered miRNAs
(< 50kb from Mir-2-o124)
Mir-71-o2 NNSW01000131_dd_Smes_g4_131: 1191188-1191254 [+] UCSC Ensembl
Mir-2-o123 NNSW01000131_dd_Smes_g4_131: 1191304-1191374 [+] UCSC Ensembl
Mir-2-o124 NNSW01000131_dd_Smes_g4_131: 1191422-1191481 [+] UCSC Ensembl
Mir-2-o125 NNSW01000131_dd_Smes_g4_131: 1191539-1191598 [+] UCSC Ensembl
Precursor
(pre-Mir +30nt flank)
UUCAUUGAUUAUAGUUAUCUAAUUUGAAAACCUCCAAAGUGAUUGUGAAUAAAAGUUUUAUUAAUUUAAUCACAGUCAGCAUUGGUGGUUUGAAAGUAGAGUGAUCUUACAAUCGAAUCA
Get precursor sequence
Structure
        10           20        30         40        50         
UUCAUUGAUUAUAGUUA---|   A   GA     U    A -         A   AAGUUU 
                    UCUA UUU  AAACC CCAA G UGAUUGUGA UAA      \
                    AGAU GAA  UUUGG GGUU C ACUGACACU AUU      U
ACUAAGCUAACAUUCUAGUG^   -   AG     U    A G         A   UAAUUA 
.       110       100         90        80        70        60
Deep sequencing
Go to detailed chart
CommentIt is not clear either from phylogenetic or syntenic information how many Mir-2 genes were present in the last common ancestor of protostomes and how the multiple paralogues in lophotrochozoans relate to the four Mir-2 genes in arthropods. Thus all lophotrochozoan genes aside from Mir-2-P12 are classified as orphans pending further data and analysis.
3' NTU No
MotifsNo
Tissue expression
 +
Ag Ag Di Gf Ne Ph Se Se Se Se Se Se Se Se Se Se Se Wh Wh Wh
Mature sequence

Sme-Mir-2-o124_5p

mirBase accessionMIMAT0012125
Sequence
0- CCUCCAAAGUGAUUGUGAAUAA -22
Get sequence
Star sequence

Sme-Mir-2-o124_3p*

mirBase accessionMIMAT0004019
Sequence
37- AAUCACAGUCAGCAUUGGUGGUU -60
Get sequence