MirGeneDB 3.0

MirGeneDB ID

Sme-Mir-2-o128

Family name MIR-2 (all species)
Seed AUCACAG
Species Freshwater planarian (Schmidtea mediterranea)
MiRBase ID sme-mir-2e
Paralogues Sme-Mir-2-o122a  Sme-Mir-2-o122b  Sme-Mir-2-o123  Sme-Mir-2-o124  Sme-Mir-2-o125  Sme-Mir-2-o126  Sme-Mir-2-o127  Sme-Mir-2-o129 
Orthologues Gsp-Mir-2  Ple-Mir-2 
Node of Origin (locus) S. mediterranea
Node of Origin (family) Protostomia
Genome context
(Sme_GCA_002600895.1_ASM260089v1_alt)
NNSW01000025_dd_Smes_g4_25: 5887731-5887790 [+] UCSC Ensembl
Clustered miRNAs
(< 50kb from Mir-2-o128)
Mir-71-o4 NNSW01000025_dd_Smes_g4_25: 5887508-5887571 [+] UCSC Ensembl
Mir-2-o127 NNSW01000025_dd_Smes_g4_25: 5887622-5887680 [+] UCSC Ensembl
Mir-2-o128 NNSW01000025_dd_Smes_g4_25: 5887731-5887790 [+] UCSC Ensembl
Precursor
(pre-Mir +30nt flank)
UCUAUGAACGGCUAUUUAUAGGUCAGAUGAAACCUAGUUGGUUGCGAUAUGUUGCCAUUCAAUACCAUAUCACAGCUUGCUCUAGGUUUAAUCUCGACUUAUUUUUCUCAUCAGUCCUAU
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Structure
        10         20         30          40        50        
UCUAUGAACGGCUAUUU-       -    G        UU--|    C      UUGCCA 
                  AUAGGUC AGAU AAACCUAG    GGUUG GAUAUG      U
                  UAUUCAG UCUA UUUGGAUC    UCGAC CUAUAC      U
UAUCCUGACUACUCUUUU       C    A        UCGU^    A      CAUAAC 
.       110       100        90        80        70        60
Deep sequencing
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CommentIt is not clear either from phylogenetic or syntenic information how many Mir-2 genes were present in the last common ancestor of protostomes and how the multiple paralogues in lophotrochozoans relate to the four Mir-2 genes in arthropods. Thus all lophotrochozoan genes aside from Mir-2-P12 are classified as orphans pending further data and analysis.
3' NTU No
MotifsNo
Tissue expression
 +
Ag Ag Di Gf Ne Ph Se Se Se Se Se Se Se Se Se Se Se Wh Wh Wh
Star sequence

Sme-Mir-2-o128_5p*

mirBase accessionMIMAT0011400
Sequence
0- AACCUAGUUGGUUGCGAUAUG -21
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Mature sequence

Sme-Mir-2-o128_3p

mirBase accessionMIMAT0011401
Sequence
37- UAUCACAGCUUGCUCUAGGUUUA -60
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