MirGeneDB 3.0
MirGeneDB ID

Sme-Mir-2-o126

Family name MIR-2 (all species)
Seed UCAUCAA
Species Freshwater planarian (Schmidtea mediterranea)
MiRBase ID sme-mir-2c
Paralogues Sme-Mir-2-o122a  Sme-Mir-2-o122b  Sme-Mir-2-o123  Sme-Mir-2-o124  Sme-Mir-2-o125  Sme-Mir-2-o127  Sme-Mir-2-o128  Sme-Mir-2-o129 
Orthologues Gsp-Mir-2  Ple-Mir-2 
Node of Origin (locus) S. mediterranea
Node of Origin (family) Protostomia
Genome context
(Sme_GCA_002600895.1_ASM260089v1_alt)		 NNSW01000006_dd_Smes_g4_6: 2195588-2195642 [+] UCSC Ensembl
Clustered miRNAs
(< 50kb from Mir-2-o126)		 Mir-71-o3 NNSW01000006_dd_Smes_g4_6: 2195478-2195544 [+] UCSC Ensembl
Mir-2-o126 NNSW01000006_dd_Smes_g4_6: 2195588-2195642 [+] UCSC Ensembl
Precursor
(pre-Mir +30nt flank)
AUCGUCAUUAUUUCUUUUUCAAAUACAAAAAUCAUCAAUUUGGUCUGUUAUAAAUGGCUUUUAUCACAGCCAAAACUGAUGAUCUUAUAAAUUUGUCAAACAUCCCAAUUUAGCA
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Structure
        10         20        30          40        50       
AUCGUCAUUAUUUCUUUUU-     ACAAAA-       A-|    U    U   AAUG 
                    CAAAU       AUCAUCA  UUUGG CUGU AUA    \
                    GUUUA       UAGUAGU  AAACC GACA UAU    G
ACGAUUUAACCCUACAAACU     AAUAUUC       CA^    -    C   UUUC 
   110       100        90        80        70         60
Deep sequencing
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CommentIt is not clear either from phylogenetic or syntenic information how many Mir-2 genes were present in the last common ancestor of protostomes and how the multiple paralogues in lophotrochozoans relate to the four Mir-2 genes in arthropods. Thus all lophotrochozoan genes aside from Mir-2-P12 are classified as orphans pending further data and analysis.
3' NTU No
MotifsCNNC at 3p(+17)
Tissue expression
-   +
Se Se Se Se Se Se Se Se Se Se Se Se Ne Wh Wh Wh
Mature sequence

Sme-Mir-2-o126_5p
mirBase accessionMIMAT0012094
Sequence 
0- AUCAUCAAUUUGGUCUGUUAUA -22
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Star sequence

Sme-Mir-2-o126_3p*
mirBase accessionMIMAT0003967
Sequence 
33- UCACAGCCAAAACUGAUGAUCU -55
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