Mir-2-o126

MirGeneDB ID

Sme-Mir-2-o126

Family name

MIR-2 (all species)

Seed

UCAUCAA

Species

Freshwater planarian (Schmidtea mediterranea)

MiRBase ID

sme-mir-2c

Paralogues

Sme-Mir-2-o122a Sme-Mir-2-o122b Sme-Mir-2-o123 Sme-Mir-2-o124 Sme-Mir-2-o125 Sme-Mir-2-o127 Sme-Mir-2-o128 Sme-Mir-2-o129

Orthologues

Gsp-Mir-2 Ple-Mir-2

Node of Origin (locus)

S. mediterranea

Node of Origin (family)

Protostomia

Genome context
(Sme_GCA_002600895.1_ASM260089v1_alt)

NNSW01000006_dd_Smes_g4_6: 2195588-2195642 [+] UCSC Ensembl

Clustered miRNAs
(< 50kb from Mir-2-o126)

Mir-71-o3 NNSW01000006_dd_Smes_g4_6: 2195478-2195544 [+] UCSC Ensembl
Mir-2-o126 NNSW01000006_dd_Smes_g4_6: 2195588-2195642 [+] UCSC Ensembl

Precursor
(pre-Mir +30nt flank)

AUCGUCAUUAUUUCUUUUUCAAAUACAAAAAUCAUCAAUUUGGUCUGUUAUAAAUGGCUUUUAUCACAGCCAAAACUGAUGAUCUUAUAAAUUUGUCAAACAUCCCAAUUUAGCA

Get precursor sequence

Structure

        10         20        30          40        50       
AUCGUCAUUAUUUCUUUUU-     ACAAAA-       A-|    U    U   AAUG 
                    CAAAU       AUCAUCA  UUUGG CUGU AUA    \
                    GUUUA       UAGUAGU  AAACC GACA UAU    G
ACGAUUUAACCCUACAAACU     AAUAUUC       CA^    -    C   UUUC 
   110       100        90        80        70         60

Deep sequencing

Go to detailed chart

Comment

It is not clear either from phylogenetic or syntenic information how many Mir-2 genes were present in the last common ancestor of protostomes and how the multiple paralogues in lophotrochozoans relate to the four Mir-2 genes in arthropods. Thus all lophotrochozoan genes aside from Mir-2-P12 are classified as orphans pending further data and analysis.

3' NTU

Motifs

CNNC at 3p(+17)

Tissue expression

Ag	Ag	Di	Gf	Ne	Ph	Se	Se	Se	Se	Se	Se	Se	Se	Se	Se	Se	Wh	Wh	Wh

Mature sequence

Sme-Mir-2-o126_5p

mirBase accession

MIMAT0012094

Sequence

0- AUCAUCAAUUUGGUCUGUUAUA -22

Get sequence

Star sequence

Sme-Mir-2-o126_3p*

mirBase accession

MIMAT0003967

Sequence

33- UCACAGCCAAAACUGAUGAUCU -55

Get sequence