Mir-23-P2a

MirGeneDB ID

Dre-Mir-23-P2a

Family name

MIR-23 (all species)

Seed

UCACAUU

Species

Zebrafish (Danio rerio)

MiRBase ID

dre-mir-23b

Paralogues

Dre-Mir-23-P1 Dre-Mir-23-P2b Dre-Mir-23-P3 Dre-Mir-23-P4a

Orthologues

Aca-Mir-23-P2 Ami-Mir-23-P2 Bta-Mir-23-P2 Cfa-Mir-23-P2 Cli-Mir-23-P2 Cmi-Mir-23-P2 Cpi-Mir-23-P2 Cpo-Mir-23-P2 Dno-Mir-23-P2 Ete-Mir-23-P2 Gga-Mir-23-P2 Gja-Mir-23-P2 Hsa-Mir-23-P2 Lch-Mir-23-P2 Loc-Mir-23-P2 Mal-Mir-23-P2a Mdo-Mir-23-P2 Mml-Mir-23-P2 Mmu-Mir-23-P2 Mun-Mir-23-P2 Oan-Mir-23-P2 Ocu-Mir-23-P2 Pbv-Mir-23-P2 Pma-Mir-23-o2 Rno-Mir-23-P2 Sha-Mir-23-P2 Spt-Mir-23-P2 Sto-Mir-23-P2 Tgu-Mir-23-P2 Xtr-Mir-23-P2

Node of Origin (locus)

Clupeocephala

Node of Origin (family)

Vertebrata

Genome context
(danRer11)

chr10: 15954588-15954651 [+] UCSC Ensembl

Clustered miRNAs
(< 50kb from Mir-23-P2a)

Mir-23-P2a chr10: 15954588-15954651 [+] UCSC Ensembl
Mir-27-P2a chr10: 15954740-15954804 [+] UCSC Ensembl
Mir-24-P2a chr10: 15960847-15960904 [+] UCSC Ensembl

Precursor
(pre-Mir +30nt flank)

GACGGGGGUCUCCAGCUUGUUGUGGCUGUGUGGGUUCUUGGCAUGCUGAUUUGUGACUGUAGUAAAAAAAAAUCACAUUGCCAGGGAUUACCACACUACCACGGCAUUACCAGCAGUUCAUGAG

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Structure

        10         20        30          40         50        60 
GACGGGGGUCUCCAGCU-        CU      --         -|  C      GUGACUGU 
                  UGUUGUGG  GUGUGG  GUUCUUGGC AUG UGAUUU        \
                  ACGGCACC  CACACC  UAGGGACCG UAC ACUAAA        A
GAGUACUUGACGACCAUU        AU      AU         U^  -      AAAAAAUG 
  120       110       100        90        80         70

Deep sequencing

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Comment

For many taxa there is often a higher set of 5p reads shifted -1. However the 5'moR reads support what is annotated here as the actual Drosha cut in relation to the phylogenetically conserved Group 2 3' arm.

3' NTU

Yes

Motifs

CNNC at 3p(+17), UGUG in loop

Tissue expression

Br	Br	Em	Ey	Gu	Gu	He	Li	Li	Ov	Te

Star sequence

Dre-Mir-23-P2a_5p*

mirBase accession

None

Sequence

0- UGGGUUCUUGGCAUGCUGAUUU -22

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Mature sequence

Dre-Mir-23-P2a_3p

mirBase accession

MIMAT0001791

Sequence

41- AUCACAUUGCCAGGGAUUACCAC -64

Get sequence

Proposed targets

TargetScanFish: dre-miR-23b