Mir-10-P2b

MirGeneDB ID

Eca-Mir-10-P2b

Family name

MIR-10 (all species)

Seed

ACCCGUA

Species

Horse (Equus caballus)

MiRBase ID

eca-mir-99b

Paralogues

Eca-Mir-10-P1b-v1 Eca-Mir-10-P1b-v2 Eca-Mir-10-P1c-v1 Eca-Mir-10-P1c-v2 Eca-Mir-10-P2c Eca-Mir-10-P2d Eca-Mir-10-P3b Eca-Mir-10-P3c Eca-Mir-10-P3d

Orthologues

Aae-Mir-10-P2 Aca-Mir-10-P2b Adi-Mir-10 Aga-Mir-10-P2 Agr-Mir-10-P2 Ami-Mir-10-P2b Asp-Mir-10 Bfl-Mir-10-P2-v1 Bfl-Mir-10-P2-v2 Bge-Mir-10-P2 Bko-Mir-10-P2 Bla-Mir-10-P2-v1 Bla-Mir-10-P2-v2 Bpl-Mir-10-P2 Bta-Mir-10-P2b Cbr-Mir-10-P2 Cel-Mir-10-P2 Cfa-Mir-10-P2b Cin-Mir-10-P2 Cja-Mir-10-P2b Cpi-Mir-10-P2b Cpo-Mir-10-P2b Cte-Mir-10-P2 Dan-Mir-10-P2 Dgr-Mir-10-P2 Dlo-Mir-10-P2 Dma-Mir-10-P2 Dme-Mir-10-P2 Dmo-Mir-10-P2 Dpu-Mir-10-P2 Dsi-Mir-10-P2 Dya-Mir-10-P2 Eba-Mir-10-P2 Ete-Mir-10-P2b Gja-Mir-10-P2b Gpa-Mir-10-P2 Gsp-Mir-10-P2 Hru-Mir-10-P2 Hsa-Mir-10-P2b Isc-Mir-10-P2 Laf-Mir-10-P2b Lan-Mir-10-P2 Lch-Mir-10-P2b Lgi-Mir-10-P2 Lhy-Mir-10-P2 Llo-Mir-10-P2 Mgi-Mir-10-P2 Mml-Mir-10-P2b Mmr-Mir-10-P2b Mmu-Mir-10-P2b Mom-Mir-10-P2 Mun-Mir-10-P2b Neu-Mir-10-P2b Npo-Mir-10-P2 Nve-Mir-10 Oan-Mir-10-P2b Obi-Mir-10-P2 Ocu-Mir-10-P2b Ofu-Mir-10-P2 Ovu-Mir-10-P2 Pab-Mir-10-P2b Pau-Mir-10-P2 Pbv-Mir-10-P2b Pca-Mir-10-P2 Pdu-Mir-10-P2 Pfl-Mir-10-P2 Ple-Mir-10-P2 Pmi-Mir-10-P2 Pve-Mir-10-P2 Rno-Mir-10-P2b Rph-Mir-10-P2 Sha-Mir-10-P2b Sko-Mir-10-P2 Snu-Mir-10-P2 Spt-Mir-10-P2b Sto-Mir-10-P2b Tca-Mir-10-P2 Tur-Mir-10-P2 Xbo-Mir-10-P2 Xbo-Mir-10-P2-as Xla-Mir-10-P2b1 Xla-Mir-10-P2b2 Xtr-Mir-10-P2b

Node of Origin (locus)

Gnathostomata

Node of Origin (family)

Eumetazoa

Genome context
(GCA_002863925.1_EquCab3.0)

CM009157.1: 21666040-21666099 [+] UCSC Ensembl

Clustered miRNAs
(< 50kb from Mir-10-P2b)

Mir-10-P2b CM009157.1: 21666040-21666099 [+] UCSC Ensembl
Let-7-P1b CM009157.1: 21666218-21666284 [+] UCSC Ensembl
Mir-10-P3b CM009157.1: 21666722-21666781 [+] UCSC Ensembl

Precursor
(pre-Mir +30nt flank)

CGGGGGCCCGGAUUCCUGGGGCCUGGCACCCACCCGUAGAACCGACCUUGCGGGGCCUUCGCCGCACACAAGCUCGUGUCUGUGGGUCCGUGUCGGGGGCUCACCAUCGCGGCUGGGGCC

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Structure

        10        20          30        40        50         
CGGGGGCCCGGAUUCCUG      --|    CC         AC   C    CGGGGCCU 
                  GGGCCU  GGCAC  ACCCGUAGA  CGA CUUG        U
                  CUCGGG  CUGUG  UGGGUGUCU  GCU GAAC        C
CCGGGGUCGGCGCUACCA      GG^    CC         GU   C    ACACGCCG 
.       110       100        90        80        70        60

Deep sequencing

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Comment

Based on the 3' DcRNA reads in human (P2b) and platypus (P2c) it appears that this is a Group 2 miRNA.

3' NTU

Yes

Motifs

UG at 5p(-14)

Tissue expression

Ps	Bo	Ca	Em	En	En	En	En	En	En	En	Gl	He	He	Ho	Im	Ki	Li	Lo	Lu	Ma	Ma	Mi	Pl	Sp	Te	Tr	Ut	Ut	Yo

Mature sequence

Eca-Mir-10-P2b_5p

mirBase accession

MIMAT0013018

Sequence

0- CACCCGUAGAACCGACCUUGCG -22

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Star sequence

Eca-Mir-10-P2b_3p*

mirBase accession

None

Sequence

38- CAAGCUCGUGUCUGUGGGUCCG -60

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