MirGeneDB 3.0
MirGeneDB ID

Mmu-Mir-421-P2

Family name MIR-421 (all species)
Seed UCAACAG
Species House mouse (Mus musculus)
MiRBase ID mmu-mir-421
Paralogues
Orthologues Bta-Mir-421-P2  Cfa-Mir-421-P2  Cja-Mir-421-P2  Eca-Mir-421-P2  Hsa-Mir-421-P2  Laf-Mir-421-P2  Mml-Mir-421-P2  Ocu-Mir-421-P2  Pab-Mir-421-P2  Rno-Mir-421-P2 
Node of Origin (locus) Eutheria
Node of Origin (family) Eutheria
Genome context
(mm10)		 chrX: 103572930-103572986 [-] UCSC Ensembl
Clustered miRNAs
(< 50kb from Mir-421-P2)		 Mir-421-P2 chrX: 103572930-103572986 [-] UCSC Ensembl
Mir-374-P2 chrX: 103573082-103573133 [-] UCSC Ensembl
Precursor
(pre-Mir +30nt flank)
ACAGUGCCUAAUCCGGUGCACAUUGUAGGCCUCAUUAAAUGUUUGUUGAAUGAAAAAAUGAAUCAUCAACAGACAUUAAUUGGGCGCCUGCUCUGUGAUCUCCAUGGGCUCAGCUUG
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Structure
        10          20        30         40        50        
ACAGUGCCUAAUCCGGUG--    UU      -|   UUA            A   AAAA 
                    CACA  GUAGGC CUCA   AAUGUUUGUUGA UGA    \
                    GUGU  CGUCCG GGGU   UUACAGACAACU ACU    A
GUUCGACUCGGGUACCUCUA    CU      C^   UAA            -   AAGU 
     110       100        90        80        70         60
Deep sequencing
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CommentThere is a second Drosha cut -1 on the 3p arm that is monouridylated at the 3' end.
3' NTU No
MotifsUG at 5p(-14)
Tissue expression
-   +
Br Br Ce Ce Em Em He Ki Li Lu Ov Pa Sk Sp Te
Star sequence

Mmu-Mir-421-P2_5p*
mirBase accessionMIMAT0017273
Sequence 
0- CUCAUUAAAUGUUUGUUGAAUGA -23
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Proposed targets TargetScanVert: mmu-miR-421-5p
miRDB: MIMAT0017273
Mature sequence

Mmu-Mir-421-P2_3p
mirBase accessionMIMAT0004869
Sequence 
34- AUCAACAGACAUUAAUUGGGCGC -57
Get sequence
Proposed targets microrna.org: MIMAT0004869
TargetScanVert: mmu-miR-421-3p
miRDB: MIMAT0004869