MirGeneDB 3.0
MirGeneDB ID

Ocu-Mir-421-P2

Family name MIR-421 (all species)
Seed UCAACAG
Species Rabbit (Oryctolagus cuniculus)
MiRBase ID ocu-mir-421
Paralogues Ocu-Mir-421-P1-v1  Ocu-Mir-421-P1-v2 
Orthologues Bta-Mir-421-P2  Cfa-Mir-421-P2  Cja-Mir-421-P2  Eca-Mir-421-P2  Hsa-Mir-421-P2  Laf-Mir-421-P2  Mml-Mir-421-P2  Mmu-Mir-421-P2  Pab-Mir-421-P2  Rno-Mir-421-P2 
Node of Origin (locus) Eutheria
Node of Origin (family) Eutheria
Genome context
(oryCun2_add)		 chrUn0059: 1593435-1593491 [+] UCSC Ensembl
Clustered miRNAs
(< 50kb from Mir-421-P2)		 Mir-374-P2 chrUn0059: 1593276-1593327 [+] UCSC Ensembl
Mir-421-P2 chrUn0059: 1593435-1593491 [+] UCSC Ensembl
Precursor
(pre-Mir +30nt flank)
ACAGUGCCUAAUCCGGUGCACAUUGUAGGCCUCAUUAAAUGUUUGUUGAAUGAAAAAAUGAAUCAUCAACAGACAUUAAUUGGGCGCCUGCUCUGUGAUCUCCAUGGGCUCAGCUUG
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Structure
        10          20        30         40        50        
ACAGUGCCUAAUCCGGUG--    UU      -|   UUA            A  AAAAA 
                    CACA  GUAGGC CUCA   AAUGUUUGUUGA UG     \
                    GUGU  CGUCCG GGGU   UUACAGACAACU AC     A
GUUCGACUCGGGUACCUCUA    CU      C^   UAA            -  UAAGU 
     110       100        90        80        70         60
Deep sequencing
CommentThere is a second Drosha cut -1 on the 3p arm that is monouridylated at the 3' end.
3' NTU No
MotifsUG at 5p(-14)
Tissue expression
-   +
He Ki Te To Wh
Star sequence

Ocu-Mir-421-P2_5p*
mirBase accessionMIMAT0048439
Sequence 
0- CUCAUUAAAUGUUUGUUGAAUG -22
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Mature sequence

Ocu-Mir-421-P2_3p
mirBase accessionMIMAT0048440
Sequence 
34- AUCAACAGACAUUAAUUGGGCGC -57
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