MirGeneDB 3.0
MirGeneDB ID

Rno-Mir-421-P2

Family name MIR-421 (all species)
Seed UCAACAG
Species Norway rat (Rattus norvegicus)
MiRBase ID rno-mir-421
Paralogues
Orthologues Bta-Mir-421-P2  Cfa-Mir-421-P2  Cja-Mir-421-P2  Eca-Mir-421-P2  Hsa-Mir-421-P2  Laf-Mir-421-P2  Mml-Mir-421-P2  Mmu-Mir-421-P2  Ocu-Mir-421-P2  Pab-Mir-421-P2 
Node of Origin (locus) Eutheria
Node of Origin (family) Eutheria
Genome context
(rn6)		 chrX: 74443502-74443558 [-] UCSC Ensembl
Clustered miRNAs
(< 50kb from Mir-421-P2)		 Mir-421-P2 chrX: 74443502-74443558 [-] UCSC Ensembl
Mir-374-P2 chrX: 74443655-74443706 [-] UCSC Ensembl
Precursor
(pre-Mir +30nt flank)
ACAGUACCUAAUCCGGUGCACACUGUAGGCCUCAUUAAAUGUUUGUUGAAUGAAAAAAUGAAUCAUCAACAGACAUUAAUUGGGCGCCUGCUCUGUGAUCUCCAUGAGCUCAGCUUC
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Structure
        10          20        30         40        50        
ACAGUACCUAAUCCGGUG--    CU      -|   UUA            A   AAAA 
                    CACA  GUAGGC CUCA   AAUGUUUGUUGA UGA    \
                    GUGU  CGUCCG GGGU   UUACAGACAACU ACU    A
CUUCGACUCGAGUACCUCUA    CU      C^   UAA            -   AAGU 
     110       100        90        80        70         60
Deep sequencing
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CommentThere is a second Drosha cut -1 on the 3p arm that is monouridylated at the 3' end.
3' NTU No
MotifsUG at 5p(-14)
Tissue expression
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Star sequence

Rno-Mir-421-P2_5p*
mirBase accessionMIMAT0001320
Sequence 
0- CUCAUUAAAUGUUUGUUGAAUGA -23
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Proposed targets microrna.org: MIMAT0001320
TargetScanVert: rno-miR-421-5p
miRDB: MIMAT0001320
Mature sequence

Rno-Mir-421-P2_3p
mirBase accessionMIMAT0017175
Sequence 
34- AUCAACAGACAUUAAUUGGGCGC -57
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Proposed targets TargetScanVert: rno-miR-421-3p
miRDB: MIMAT0017175