MirGeneDB 3.0

MirGeneDB ID

Mml-Mir-421-P2

Family name MIR-421 (all species)
Seed UCAACAG
Species Rhesus monkey (Macaca mulatta)
MiRBase ID mml-mir-421
Paralogues Mml-Mir-421-P1-v1  Mml-Mir-421-P1-v2 
Orthologues Bta-Mir-421-P2  Cfa-Mir-421-P2  Cja-Mir-421-P2  Eca-Mir-421-P2  Hsa-Mir-421-P2  Laf-Mir-421-P2  Mmu-Mir-421-P2  Ocu-Mir-421-P2  Pab-Mir-421-P2  Rno-Mir-421-P2 
Node of Origin (locus) Eutheria
Node of Origin (family) Eutheria
Genome context
(GCA_003339765.3_Mmul_10_traces)
CM014356.1: 71307801-71307857 [-] UCSC Ensembl
Clustered miRNAs
(< 50kb from Mir-421-P2)
Mir-421-P2 CM014356.1: 71307801-71307857 [-] UCSC Ensembl
Mir-374-P2 CM014356.1: 71307966-71308017 [-] UCSC Ensembl
Precursor
(pre-Mir +30nt flank)
GCAGUGCCUAAUCCGGUGCACAUUGUAGGCCUCAUUAAAUGUUUGUUGAAUGAAAAAAUGAAUCAUCAACAGACAUUAAUUGGGCGCCUGCUCUGUGAUCUCCAUGGGCUCAGCUUG
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Structure
        10          20        30         40        50        
GCAGUGCCUAAUCCGGUG--    UU      -|   UUA            A   AAAA 
                    CACA  GUAGGC CUCA   AAUGUUUGUUGA UGA    \
                    GUGU  CGUCCG GGGU   UUACAGACAACU ACU    A
GUUCGACUCGGGUACCUCUA    CU      C^   UAA            -   AAGU 
     110       100        90        80        70         60
Deep sequencing
CommentThere is a second Drosha cut -1 on the 3p arm that is monouridylated at the 3' end.
3' NTU No
MotifsUG at 5p(-14)
Star sequence

Mml-Mir-421-P2_5p*

mirBase accessionNone
Sequence
0- CUCAUUAAAUGUUUGUUGAAUGA -23
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Mature sequence

Mml-Mir-421-P2_3p

mirBase accessionMIMAT0006319
Sequence
34- AUCAACAGACAUUAAUUGGGCGC -57
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Proposed targets TargetScanVert: mml-miR-421