MirGeneDB 3.0
MirGeneDB ID

Neu-Let-7-P2a3

Family name LET-7 (all species)
Seed GAGGUAG
Species Tammar Wallaby (Notamacropus eugenii)
MiRBase ID
Paralogues Neu-Let-7-P1c  Neu-Let-7-P1d  Neu-Let-7-P2a2  Neu-Let-7-P2b1  Neu-Let-7-P2b2  Neu-Let-7-P2c1  Neu-Let-7-P2c2 
Orthologues Aae-Let-7  Aca-Let-7-P2a3  Aga-Let-7  Agr-Let-7  Ami-Let-7-P2a3  Bge-Let-7  Bko-Let-7  Bpl-Let-7  Bta-Let-7-P2a3  Cfa-Let-7-P2a3  Cja-Let-7-P2a3  Cpi-Let-7-P2a3  Cpo-Let-7-P2a3  Cte-Let-7  Dan-Let-7  Dlo-Let-7  Dma-Let-7  Dme-Let-7  Dmo-Let-7  Dno-Let-7-P2a3  Dpu-Let-7  Dre-Let-7-P2a3a  Dre-Let-7-P2a3b  Dsi-Let-7  Dya-Let-7  Eba-Let-7  Eca-Let-7-P2a3  Egr-Let-7  Esc-Let-7  Ete-Let-7-P2a3  Gja-Let-7-P2a3  Gmo-Let-7-P2a3a  Gmo-Let-7-P2a3b  Gpa-Let-7  Gsa-Let-7  Gsp-Let-7  Hme-Let-7  Hmi-Let-7  Hru-Let-7  Hsa-Let-7-P2a3  Isc-Let-7  Laf-Let-7-P2a3  Lan-Let-7  Lch-Let-7-P2a3  Lgi-Let-7  Lhy-Let-7  Llo-Let-7  Loc-Let-7-P2a3  Mal-Let-7-P2a3a  Mal-Let-7-P2a3b  Mdo-Let-7-P2a3  Mgi-Let-7  Mml-Let-7-P2a3  Mmr-Let-7-P2a3  Mmu-Let-7-P2a3  Mom-Let-7  Mun-Let-7-P2a3  Npo-Let-7  Oan-Let-7-P2a3  Obi-Let-7  Ocu-Let-7-P2a3  Ofu-Let-7  Ovu-Let-7  Pab-Let-7-P2a3  Pau-Let-7  Pbv-Let-7-P2a3  Pca-Let-7  Pcr-Let-7  Pdu-Let-7  Pfl-Let-7  Ple-Let-7  Pmi-Let-7  Pve-Let-7  Rno-Let-7-P2a3  Rph-Let-7  Sha-Let-7-P2a3  Sko-Let-7  Sma-Let-7  Sne-Let-7  Snu-Let-7  Spt-Let-7-P2a3  Spu-Let-7  Sro-Let-7  Sto-Let-7-P2a3  Tca-Let-7  Tgu-Let-7-P2a3  Tni-Let-7-P2a3a  Tni-Let-7-P2a3b  Tur-Let-7  War-Let-7  Xbo-Let-7  Xla-Let-7-P2a3d  Xtr-Let-7-P2a3 
Node of Origin (locus) Gnathostomata
Node of Origin (family) Bilateria
Genome context
(GCA_028372415.1_mMacEug1.pri)		 CM051820.1: 102401585-102401655 [-] UCSC Ensembl
Precursor
(pre-Mir +30nt flank)
CUCACAGAAGAAUCUCUGUGCCCCGCGGGAUGAGGUAGUAGAUUGUAUAGUUUUAGGGUCACACCCGAUCUUGGAGAUAACUAUACAGUCUACUGUCUUUCUCACGGAGCUUCACUCUCACCACAUCCAGC
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Structure
        10          20        30        40        50        60     
CUCACAGAAGAAUCUCUGU--| C   C    U   GU                UUAGGGUCACAC 
                     GC CCG GGGA GAG  AGUAGAUUGUAUAGUU            C
                     CG GGC CUCU UUC  UCAUCUGACAUAUCAA            C
CGACCUACACCACUCUCACUU^ A   A    -   UG                UAGAGGUUCUAG 
 .       120       110       100         90        80        70
Deep sequencing
CommentThe 3' uridine appears to be templated but is here considered a Group 2 miRNA based on phylogenetic grounds.
3' NTU Yes
MotifsUG at 5p(-14), CNNC at 3p(+17)
Mature sequence

Neu-Let-7-P2a3_5p
mirBase accessionNone
Sequence 
0- UGAGGUAGUAGAUUGUAUAGUU -22
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Star sequence

Neu-Let-7-P2a3_3p*
mirBase accessionNone
Sequence 
50- CUAUACAGUCUACUGUCUUUC -71
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