Let-7-P2a3b

MirGeneDB ID

Dre-Let-7-P2a3b

Family name

LET-7 (all species)

Seed

GAGGUAG

Species

Zebrafish (Danio rerio)

MiRBase ID

dre-let-7g-1

Paralogues

Dre-Let-7-P1b1 Dre-Let-7-P1b2 Dre-Let-7-P1c1 Dre-Let-7-P1c2 Dre-Let-7-P1d1 Dre-Let-7-P1d2 Dre-Let-7-P2a1a Dre-Let-7-P2a2a Dre-Let-7-P2a2b Dre-Let-7-P2a3a Dre-Let-7-P2a4a Dre-Let-7-P2a4b Dre-Let-7-P2b1a Dre-Let-7-P2b2a Dre-Let-7-P2b2b Dre-Let-7-P2b3a Dre-Let-7-P2b4a Dre-Let-7-P2b4b Dre-Let-7-P2c2b Dre-Let-7-P2c3

Orthologues

Aae-Let-7 Aca-Let-7-P2a3 Aga-Let-7 Agr-Let-7 Ami-Let-7-P2a3 Bge-Let-7 Bko-Let-7 Bpl-Let-7 Bta-Let-7-P2a3 Cfa-Let-7-P2a3 Cja-Let-7-P2a3 Cpi-Let-7-P2a3 Cpo-Let-7-P2a3 Cte-Let-7 Dan-Let-7 Dlo-Let-7 Dma-Let-7 Dme-Let-7 Dmo-Let-7 Dno-Let-7-P2a3 Dpu-Let-7 Dsi-Let-7 Dya-Let-7 Eba-Let-7 Eca-Let-7-P2a3 Egr-Let-7 Esc-Let-7 Ete-Let-7-P2a3 Gja-Let-7-P2a3 Gmo-Let-7-P2a3a Gmo-Let-7-P2a3b Gpa-Let-7 Gsa-Let-7 Gsp-Let-7 Hme-Let-7 Hmi-Let-7 Hru-Let-7 Hsa-Let-7-P2a3 Isc-Let-7 Laf-Let-7-P2a3 Lan-Let-7 Lch-Let-7-P2a3 Lgi-Let-7 Lhy-Let-7 Llo-Let-7 Loc-Let-7-P2a3 Mal-Let-7-P2a3a Mal-Let-7-P2a3b Mdo-Let-7-P2a3 Mgi-Let-7 Mml-Let-7-P2a3 Mmr-Let-7-P2a3 Mmu-Let-7-P2a3 Mom-Let-7 Mun-Let-7-P2a3 Neu-Let-7-P2a3 Npo-Let-7 Oan-Let-7-P2a3 Obi-Let-7 Ocu-Let-7-P2a3 Ofu-Let-7 Ovu-Let-7 Pab-Let-7-P2a3 Pau-Let-7 Pbv-Let-7-P2a3 Pca-Let-7 Pcr-Let-7 Pdu-Let-7 Pfl-Let-7 Ple-Let-7 Pmi-Let-7 Pve-Let-7 Rno-Let-7-P2a3 Rph-Let-7 Sha-Let-7-P2a3 Sko-Let-7 Sma-Let-7 Sne-Let-7 Snu-Let-7 Spt-Let-7-P2a3 Spu-Let-7 Sro-Let-7 Sto-Let-7-P2a3 Tca-Let-7 Tgu-Let-7-P2a3 Tni-Let-7-P2a3a Tni-Let-7-P2a3b Tur-Let-7 War-Let-7 Xbo-Let-7 Xla-Let-7-P2a3d Xtr-Let-7-P2a3

Node of Origin (locus)

Clupeocephala

Node of Origin (family)

Bilateria

Genome context
(danRer11)

chr23: 18382469-18382538 [-] UCSC Ensembl

Precursor
(pre-Mir +30nt flank)

GCAGGGUAGCAGGCAUUGGGGGCUGUGGAAUGAGGUAGUAGUUUGUAUAGUUUGGGAUCACACCAGAUCUGGGAGAUAACUAUACAGCCUACUGUCUUUCUCACAGCUGCUCCUUCACAUCAGACCCUCC

Get precursor sequence

Structure

        10          20        30        40        50        60     
GCAGGGUAGCAGGCAUU--| G        AAU   GU     U          UGGGAUCACACC 
                   GG GGCUGUGG   GAG  AGUAG UUGUAUAGUU            \
                   UC UCGACACU   UUC  UCAUC GACAUAUCAA            A
CCUCCCAGACUACACUUCC^ G        CU-   UG     C          UAGAGGGUCUAG 
.       120       110       100         90        80        70

Deep sequencing

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Comment

Although there is a templated T at the 3' end of the 3p arm, the post-transcriptional addition of a terminal 3' U is supported by the 3' DcRNA reads.

3' NTU

Yes

Motifs

UG at 5p(-14), CNNC at 3p(+17)

Tissue expression

Br	Br	Em	Ey	Gu	Gu	He	Li	Li	Ov	Te

Mature sequence

Dre-Let-7-P2a3b_5p

mirBase accession

MIMAT0001765

Sequence

0- UGAGGUAGUAGUUUGUAUAGUU -22

Get sequence

Proposed targets

TargetScanFish: dre-let-7g

Star sequence

Dre-Let-7-P2a3b_3p*

mirBase accession

None

Sequence

49- CUAUACAGCCUACUGUCUUUC -70

Get sequence