Mir-450-P1b

MirGeneDB ID

Rno-Mir-450-P1b

Family name

MIR-450 (all species)

Seed

UUUGCGA

Species

Norway rat (Rattus norvegicus)

MiRBase ID

rno-mir-450b-2

Paralogues

Rno-Mir-450-P1a Rno-Mir-450-P2a Rno-Mir-450-P2b Rno-Mir-450-P3a Rno-Mir-450-P3b

Orthologues

Bta-Mir-450-P1 Cfa-Mir-450-P1 Cja-Mir-450-P1 Cpo-Mir-450-P1 Dno-Mir-450-P1 Eca-Mir-450-P1 Hsa-Mir-450-P1 Laf-Mir-450-P1 Mml-Mir-450-P1 Mmr-Mir-450-P1 Mmu-Mir-450-P1 Ocu-Mir-450-P1 Pab-Mir-450-P1

Node of Origin (locus)

R. norvegicus

Node of Origin (family)

Eutheria

Genome context
(rn6)

chrX: 158153261-158153317 [+] UCSC Ensembl

Clustered miRNAs
(< 50kb from Mir-450-P1b)

Mir-15-P1c4 chrX: 158148183-158148240 [+] UCSC Ensembl
Mir-15-P2c4 chrX: 158148481-158148543 [+] UCSC Ensembl
Mir-351-P1b chrX: 158149221-158149280 [+] UCSC Ensembl
Mir-542-P1c chrX: 158152156-158152216 [+] UCSC Ensembl
Mir-450-P1b chrX: 158153261-158153317 [+] UCSC Ensembl
Mir-450-P2b chrX: 158153394-158153450 [+] UCSC Ensembl
Mir-542-P1b chrX: 158158895-158158955 [+] UCSC Ensembl

Precursor
(pre-Mir +30nt flank)

GGAGAAAGGCAAAGCCAGAUGCUGAACUAUUUUUGCGAUGUGUUCCUAAUAUGUACUAUGAGUGUAUUGGGGACGCUUCGCAUUCAUGGUUCUGCAUCAGUCAUAUGGAGUGAAGAC

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Structure

        10          20        30        40        50        
GGAGAAAGGCAAAGCCA--|    U       UUU     U            UGUACU 
                   GAUGC GAACUAU   UGCGA GUGUUCCUAAUA      \
                   CUACG CUUGGUA   ACGCU CGCAGGGGUUAU      A
CAGAAGUGAGGUAUACUGA^    U       CUU     U            GUGAGU 
     110       100        90        80        70        60

Deep sequencing

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3' NTU

Motifs

UGUG in loop

Tissue expression

Dr	Dr	Ad	Bi	Bi	Bi	Bi	Br	Br	Br	Br	Ce	Ce	Ce	Ce	Co	Co	Co	Co	Du	Du	Du	Du	Fa	He	He	He	Hi	Hi	Il	Il	Je	Je	Ki	Ki	Ki	Ki	Ki	La	Li	Li	Li	Li	Li	Li	Lu	Me	Me	Mu	Ov	Pa	Pa	Pa	Sk	Sm	So	So	So	So	Sp	St	St	St	St	Te	Te	Th	Ut	Wh

Mature sequence

Rno-Mir-450-P1b_5p

mirBase accession

MIMAT0035746

Sequence

0- UUUUGCGAUGUGUUCCUAAUA -21

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Star sequence

Rno-Mir-450-P1b_3p*

mirBase accession

MIMAT0035747

Sequence

35- AUUGGGGACGCUUCGCAUUCAU -57

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