Mir-154-P31

MirGeneDB ID

Rno-Mir-154-P31

Family name

MIR-154 (all species)

Seed

GGUCGAC

Species

Norway rat (Rattus norvegicus)

MiRBase ID

rno-mir-412

Paralogues

Rno-Mir-154-P1 Rno-Mir-154-P2-v1 Rno-Mir-154-P2-v2 Rno-Mir-154-P3-v1 Rno-Mir-154-P3-v2 Rno-Mir-154-P4 Rno-Mir-154-P6a-v1 Rno-Mir-154-P6a-v2 Rno-Mir-154-P7 Rno-Mir-154-P8-o1 Rno-Mir-154-P9 Rno-Mir-154-P10 Rno-Mir-154-P11 Rno-Mir-154-P12 Rno-Mir-154-P15 Rno-Mir-154-P17 Rno-Mir-154-P18 Rno-Mir-154-P19 Rno-Mir-154-P24 Rno-Mir-154-P25 Rno-Mir-154-P26 Rno-Mir-154-P28-v1 Rno-Mir-154-P28-v2 Rno-Mir-154-P29 Rno-Mir-154-P30 Rno-Mir-154-P32 Rno-Mir-154-P33

Orthologues

Bta-Mir-154-P31 Cfa-Mir-154-P31 Cja-Mir-154-P31 Cpo-Mir-154-P31 Dno-Mir-154-P31 Eca-Mir-154-P31 Ete-Mir-154-P31 Hsa-Mir-154-P31 Laf-Mir-154-P31 Mml-Mir-154-P31 Mmr-Mir-154-P31 Mmu-Mir-154-P31 Pab-Mir-154-P31

Node of Origin (locus)

Eutheria

Node of Origin (family)

Eutheria

Genome context
(rn6)

chr6: 133893579-133893634 [+] UCSC Ensembl

Clustered miRNAs
(< 50kb from Mir-154-P31)

Mir-154-P1 chr6: 133857715-133857772 [+] UCSC Ensembl
Mir-154-P2-v2 chr6: 133858858-133858915 [+] UCSC Ensembl
Mir-154-P2-v1 chr6: 133858859-133858914 [+] UCSC Ensembl
Mir-154-P3-v1 chr6: 133859329-133859383 [+] UCSC Ensembl
Mir-154-P3-v2 chr6: 133859330-133859382 [+] UCSC Ensembl
Mir-154-P4 chr6: 133860500-133860556 [+] UCSC Ensembl
Mir-154-P6a-v1 chr6: 133861214-133861269 [+] UCSC Ensembl
Mir-154-P6a-v2 chr6: 133861214-133861269 [+] UCSC Ensembl
Mir-154-P7 chr6: 133861509-133861566 [+] UCSC Ensembl
Mir-154-P8-o1 chr6: 133862190-133862249 [+] UCSC Ensembl
Mir-154-P9 chr6: 133864385-133864440 [+] UCSC Ensembl
Mir-154-P10 chr6: 133864729-133864785 [+] UCSC Ensembl
Mir-666 chr6: 133866541-133866601 [+] UCSC Ensembl
Mir-154-P11 chr6: 133866672-133866729 [+] UCSC Ensembl
Mir-154-P12 chr6: 133868298-133868357 [+] UCSC Ensembl
Mir-667 chr6: 133869584-133869647 [+] UCSC Ensembl
Mir-376-P2 chr6: 133872453-133872510 [+] UCSC Ensembl
Mir-376-P4 chr6: 133873110-133873167 [+] UCSC Ensembl
Mir-376-P5 chr6: 133873618-133873675 [+] UCSC Ensembl
Mir-154-P15 chr6: 133874161-133874223 [+] UCSC Ensembl
Mir-154-P17 chr6: 133876615-133876677 [+] UCSC Ensembl
Mir-154-P18 chr6: 133877137-133877194 [+] UCSC Ensembl
Mir-154-P19 chr6: 133877840-133877901 [+] UCSC Ensembl
Mir-544 chr6: 133879179-133879235 [+] UCSC Ensembl
Mir-154-P24 chr6: 133884190-133884247 [+] UCSC Ensembl
Mir-134 chr6: 133884554-133884614 [+] UCSC Ensembl
Mir-154-P25 chr6: 133885310-133885368 [+] UCSC Ensembl
Mir-154-P26 chr6: 133888600-133888657 [+] UCSC Ensembl
Mir-154-P28-v2 chr6: 133889296-133889351 [+] UCSC Ensembl
Mir-154-P28-v1 chr6: 133889297-133889350 [+] UCSC Ensembl
Mir-154-P29 chr6: 133890697-133890756 [+] UCSC Ensembl
Mir-541 chr6: 133892668-133892733 [+] UCSC Ensembl
Mir-154-P30 chr6: 133893432-133893485 [+] UCSC Ensembl
Mir-154-P31 chr6: 133893579-133893634 [+] UCSC Ensembl
Mir-154-P32 chr6: 133893706-133893761 [+] UCSC Ensembl
Mir-154-P33 chr6: 133894007-133894062 [+] UCSC Ensembl
Mir-3072 chr6: 133898823-133898879 [+] UCSC Ensembl

Precursor
(pre-Mir +30nt flank)

ACUCAUCUUCGCUCUGGGGUAUGGGACGGAUGGUCGACCAGCUGGAAAGUAAUUGUUUCUAAUGUACUUCACCUGGUCCACUAGCCGUCGGUGCCCGCCGCAGCCUGCGCCAGGAU

Get precursor sequence

Structure

        10            20        30        40        50        
ACUCAUCUUCGCUCUGG----|    G G    A    C      C   AA    AUUGUU 
                     GGUAU G ACGG UGGU GACCAG UGG  AGUA      \
                     CCGUG C UGCC AUCA CUGGUC ACU  UCAU      U
UAGGACCGCGUCCGACGCCGC^    G -    G    C      C   --    GUAAUC 
    110       100        90         80        70          60

Deep sequencing

Go to detailed chart

Comment

There is variation in the Drosha cut with a high number of reads shifted -1 relative to the phylogenetically conserved cut annotated here.

3' NTU

Motifs

UGUG in loop

Tissue expression

Dr	Dr	Ad	Bi	Bi	Bi	Bi	Br	Br	Br	Br	Ce	Ce	Ce	Ce	Co	Co	Co	Co	Du	Du	Du	Du	Fa	He	He	He	Hi	Hi	Il	Il	Je	Je	Ki	Ki	Ki	Ki	Ki	La	Li	Li	Li	Li	Li	Li	Lu	Me	Me	Mu	Ov	Pa	Pa	Pa	Sk	Sm	So	So	So	So	Sp	St	St	St	St	Te	Te	Th	Ut	Wh

Mature sequence

Rno-Mir-154-P31_5p

mirBase accession

MIMAT0017204

Sequence

0- UGGUCGACCAGCUGGAAAGUAAU -23

Get sequence

Proposed targets

TargetScanVert: rno-miR-412-5p
miRDB: MIMAT0017204

Star sequence

Rno-Mir-154-P31_3p*

mirBase accession

MIMAT0003124

Sequence

34- UACUUCACCUGGUCCACUAGCC -56

Get sequence

Proposed targets

microrna.org: MIMAT0003124
TargetScanVert: rno-miR-412-3p
miRDB: MIMAT0003124