MirGeneDB 3.0

MirGeneDB ID

Sme-Mir-277-P7a

Family name MIR-277 (all species)
Seed AAAUGCA
Species Freshwater planarian (Schmidtea mediterranea)
MiRBase ID sme-mir-277b
Paralogues Sme-Mir-277-P7b  Sme-Mir-277-P8a  Sme-Mir-277-P8b 
Orthologues Aae-Mir-277  Aga-Mir-277  Agr-Mir-277  Bge-Mir-277  Bko-Mir-277  Bpl-Mir-277  Cel-Mir-277  Dan-Mir-277  Dlo-Mir-277  Dma-Mir-277  Dme-Mir-277  Dmo-Mir-277  Dpu-Mir-277  Dsi-Mir-277  Dya-Mir-277  Eba-Mir-277  Efe-Mir-277  Egr-Mir-277-P7  Esc-Mir-277  Gpa-Mir-277  Gsp-Mir-277  Hme-Mir-277  Hru-Mir-277  Isc-Mir-277  Lgi-Mir-277  Llo-Mir-277  Mgi-Mir-277  Mom-Mir-277  Npo-Mir-277  Obi-Mir-277  Ovu-Mir-277  Pau-Mir-277  Pca-Mir-277  Pcr-Mir-277  Pdu-Mir-277  Pve-Mir-277  Rph-Mir-277  Sma-Mir-277-P7  Sne-Mir-277  Snu-Mir-277  Tca-Mir-277  Tur-Mir-277  War-Mir-277 
Node of Origin (locus) S. mediterranea
Node of Origin (family) Protostomia
Genome context
(Sme_GCA_002600895.1_ASM260089v1_alt)
NNSW01000140_dd_Smes_g4_140: 655258-655315 [-] UCSC Ensembl
Clustered miRNAs
(< 50kb from Mir-277-P7a)
Mir-277-P8a NNSW01000140_dd_Smes_g4_140: 654964-655022 [-] UCSC Ensembl
Mir-277-P7a NNSW01000140_dd_Smes_g4_140: 655258-655315 [-] UCSC Ensembl
Precursor
(pre-Mir +30nt flank)
UUUAUUUUUUACAGAUCGGUUGUAUUGAUCUUGAUCAGAAAUGCAGCUUCAGAGAAAUCACUGUGAAAAUGCAUUAUCUGGCCAAGAAAAUGAAGCCUAAAACACAUCUAAGUAGACA
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Structure
        10            20        30         40        50       
UUUAUUUUUUACAGAUC----|   G    GA     AU    -      GC    GAGAA 
                     GGUU UAUU  UCUUG  CAGA AAUGCA  UUCA     A
                     CCGA GUAA  AGAAC  GUCU UUACGU  AAGU     U
ACAGAUGAAUCUACACAAAAU^   A    A-     CG    A      AA    GUCAC 
      110       100        90         80        70        60
Deep sequencing
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CommentThe mature read is shifted 3 nt 3' relative to the other paralogues resulting in a non-canonical Dicer cut. There are no 3p reads with the usual 2 nt Dicer offset.
3' NTU No
MotifsCNNC at 3p(+17)
Tissue expression
 +
Se Se Se Se Se Se Se Se Se Se Se Se Ne Wh Wh Wh
Star sequence

Sme-Mir-277-P7a_5p*

mirBase accessionMIMAT0004008
Sequence
0- UUGAUCAGAAAUGCAGCUUCA -21
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Mature sequence

Sme-Mir-277-P7a_3p

mirBase accessionMIMAT0004009
Sequence
35- AAAAUGCAUUAUCUGGCCAAGAA -58
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