MirGeneDB 3.0
MirGeneDB ID

Hsa-Mir-34-P2a

Family name MIR-34 (all species)
Seed GGCAGUG
Species Human (Homo sapiens)
MiRBase ID hsa-mir-34b
Paralogues Hsa-Mir-34-P1  Hsa-Mir-34-P2b  Hsa-Mir-34-P3a-v1  Hsa-Mir-34-P3a-v2  Hsa-Mir-34-P3b  Hsa-Mir-34-P3c 
Orthologues Aae-Mir-34  Aca-Mir-34-P2a  Aga-Mir-34  Agr-Mir-34  Ami-Mir-34-P2a  Asu-Mir-34  Bge-Mir-34  Bta-Mir-34-P2a  Cbr-Mir-34  Cel-Mir-34  Cfa-Mir-34-P2a  Cin-Mir-34  Cja-Mir-34-P2a  Cli-Mir-34-P2a  Cmi-Mir-34-P2a  Cpi-Mir-34-P2a  Cpo-Mir-34-P2a  Cte-Mir-34  Dan-Mir-34  Dlo-Mir-34  Dma-Mir-34  Dme-Mir-34  Dmo-Mir-34  Dno-Mir-34-P2a  Dpu-Mir-34  Dre-Mir-34-P2a  Dsi-Mir-34  Dya-Mir-34  Ebu-Mir-34-P2a  Eca-Mir-34-P2a  Efe-Mir-34  Esc-Mir-34  Ete-Mir-34-P2a  Gga-Mir-34-P2a  Gja-Mir-34-P2a  Gpa-Mir-34  Gsp-Mir-34  Hmi-Mir-34  Hru-Mir-34  Isc-Mir-34  Laf-Mir-34-P2a  Lch-Mir-34-P2a  Lgi-Mir-34  Lhy-Mir-34  Llo-Mir-34  Loc-Mir-34-P2a  Mdo-Mir-34-P2a  Mgi-Mir-34  Mml-Mir-34-P2a  Mmr-Mir-34-P2a  Mmu-Mir-34-P2a  Mom-Mir-34  Mun-Mir-34-P2a  Neu-Mir-34-P2a-v1  Neu-Mir-34-P2a-v2  Npo-Mir-34  Oan-Mir-34-P2a  Obi-Mir-34  Ocu-Mir-34-P2a  Ofu-Mir-34  Ovu-Mir-34  Pab-Mir-34-P2a  Pau-Mir-34  Pbv-Mir-34-P2a  Pca-Mir-34  Pdu-Mir-34  Pfl-Mir-34  Pmi-Mir-34  Pve-Mir-34  Rno-Mir-34-P2a  Rph-Mir-34  Sha-Mir-34-P2a  Sko-Mir-34  Snu-Mir-34  Spt-Mir-34-P2a  Spu-Mir-34  Sto-Mir-34-P2a  Tca-Mir-34  Tgu-Mir-34-P2a  Tur-Mir-34  War-Mir-34  Xla-Mir-34-P2a1a  Xla-Mir-34-P2a1b  Xla-Mir-34-P2a2a  Xla-Mir-34-P2a2b  Xtr-Mir-34-P2a1  Xtr-Mir-34-P2a2 
Node of Origin (locus) Vertebrata
Node of Origin (family) Bilateria
Genome context
(hg38)		 chr11: 111512951-111513009 [+] UCSC Ensembl
Clustered miRNAs
(< 50kb from Mir-34-P2a)		 Mir-34-P2a chr11: 111512951-111513009 [+] UCSC Ensembl
Mir-34-P2b chr11: 111513451-111513505 [+] UCSC Ensembl
Precursor
(pre-Mir +30nt flank)
GCAGCCGCGGGUGCCCGGUGCUCGGUUUGUAGGCAGUGUCAUUAGCUGAUUGUACUGUGGUGGUUACAAUCACUAACUCCACUGCCAUCAAAACAAGGCACAGCAUCACCGCCGCCCGG
Get precursor sequence
Structure
        10         20        30         40        50         
GCAGCCGCGGGUGCCCG-     CG    GUA-|      UCA    C       ACUGU 
                  GUGCU  GUUU    GGCAGUG   UUAG UGAUUGU     G
                  CACGG  CAAA    CCGUCAC   AAUC ACUAACA     G
GGCCCGCCGCCACUACGA     AA    ACUA^      CUC    -       UUGGU 
       110       100        90        80         70        60
Deep sequencing
Go to detailed chart
CommentThere is a second Dicer cut +1 on the 3p arm.
3' NTU No
MotifsCNNC at 3p(+17)
Tissue expression
-   +
Dc Dc Dr Dr Xp Xp Bl Br Br Ce Ce Co Fo He Ki Le Li Li Lu Pa Pl Pl Sk Sk Sk Sm Sp Sp St Te Th Ut
Mature sequence

Hsa-Mir-34-P2a_5p
mirBase accessionMIMAT0000685
Sequence 
0- AGGCAGUGUCAUUAGCUGAUUGU -23
Get sequence
Proposed targets microrna.org: MIMAT0000685
TargetScanVert: hsa-miR-34b-5p
TargetMiner: hsa-miR-34b-5p
miRDB: MIMAT0000685
Co-mature sequence

Hsa-Mir-34-P2a_3p
mirBase accessionMIMAT0004676
Sequence 
37- AAUCACUAACUCCACUGCCAUC -59
Get sequence
Proposed targets microrna.org: MIMAT0004676
TargetScanVert: hsa-miR-34b-3p
TargetMiner: hsa-miR-34b-3p
miRDB: MIMAT0004676