Let-7-P2c3

MirGeneDB ID

Cmi-Let-7-P2c3

Family name

LET-7 (all species)

Seed

GAGGUAG

Species

Australian ghostshark (Callorhinchus milii)

MiRBase ID

Paralogues

Cmi-Let-7-P1d Cmi-Let-7-P2a1 Cmi-Let-7-P2a2 Cmi-Let-7-P2a4 Cmi-Let-7-P2b2 Cmi-Let-7-P2b4 Cmi-Let-7-P2c1 Cmi-Let-7-P2c2 Cmi-Let-7-P2c4

Orthologues

Aae-Let-7 Aca-Let-7-P2c3 Aga-Let-7 Agr-Let-7 Ami-Let-7-P2c3 Bge-Let-7 Bko-Let-7 Bpl-Let-7 Bta-Let-7-P2c3 Cfa-Let-7-P2c3 Cja-Let-7-P2c3 Cli-Let-7-P2c3 Cpi-Let-7-P2c3 Cpo-Let-7-P2c3 Cte-Let-7 Dan-Let-7 Dlo-Let-7 Dma-Let-7 Dme-Let-7 Dmo-Let-7 Dno-Let-7-P2c3 Dpu-Let-7 Dre-Let-7-P2c3 Dsi-Let-7 Dya-Let-7 Eba-Let-7 Eca-Let-7-P2c3 Egr-Let-7 Esc-Let-7 Ete-Let-7-P2c3 Gga-Let-7-P2c3 Gja-Let-7-P2c3 Gmo-Let-7-P2c3 Gpa-Let-7 Gsa-Let-7 Gsp-Let-7 Hme-Let-7 Hmi-Let-7 Hru-Let-7 Hsa-Let-7-P2c3 Isc-Let-7 Laf-Let-7-P2c3 Lan-Let-7 Lch-Let-7-P2c3 Lgi-Let-7 Lhy-Let-7 Llo-Let-7 Loc-Let-7-P2c3 Mal-Let-7-P2c3 Mdo-Let-7-P2c3 Mgi-Let-7 Mml-Let-7-P2c3 Mmr-Let-7-P2c3 Mmu-Let-7-P2c3 Mom-Let-7 Mun-Let-7-P2c3 Npo-Let-7 Oan-Let-7-P2c3 Obi-Let-7 Ocu-Let-7-P2c3 Ofu-Let-7 Ovu-Let-7 Pab-Let-7-P2c3 Pau-Let-7 Pbv-Let-7-P2c3 Pca-Let-7 Pcr-Let-7 Pdu-Let-7 Pfl-Let-7 Ple-Let-7 Pmi-Let-7 Pve-Let-7 Rno-Let-7-P2c3 Rph-Let-7 Sha-Let-7-P2c3 Sko-Let-7 Sma-Let-7 Sne-Let-7 Snu-Let-7 Spt-Let-7-P2c3 Spu-Let-7 Sro-Let-7 Sto-Let-7-P2c3 Tca-Let-7 Tgu-Let-7-P2c3 Tni-Let-7-P2c3 Tur-Let-7 War-Let-7 Xbo-Let-7 Xla-Let-7-P2c3c Xla-Let-7-P2c3d Xtr-Let-7-P2c3

Node of Origin (locus)

Gnathostomata

Node of Origin (family)

Bilateria

Genome context
(GCA_000165045.2_Callorhinchus_milii-6.1.3)

KI635869.1: 2687989-2688067 [-] UCSC Ensembl

Precursor
(pre-Mir +30nt flank)

ACCUGGAUAUUAUAUUGCCUGUGCCCAUGCAGAGGUAGUUGUUUGUACAGUUUGAGGGUUUGUGACACCACCCGGUUGAUGGAGAUAACUGUACAAGCCACUGCCUUGCUUGGGCCAGAGACCAACAUCACCCUGAAGU

Get precursor sequence

Structure

        10           20        30        40        50        60         
ACCUGGAUAUUAUAUUGC---|  U     U   G       U            UGAGGGUUUGUGACAC 
                     CUG GCCCA GCA AGGUAGU GUUUGUACAGUU                C
                     GAC CGGGU CGU UCCGUCA CGAACAUGUCAA                A
UGAAGUCCCACUACAACCAGA^  -     U   -       C            UAGAGGUAGUUGGCCC 
       130       120        110        100        90        80        70

Deep sequencing

Go to detailed chart

Comment

Based on structural and phylogenetic considerations it is assumed that the templated 3' U is a post-transcriptional addition.

3' NTU

Yes

Motifs

CNNC at 3p(+17)

Tissue expression

Bl	Br	Ey	Gi	He	In	Ki	Li	Mu	Ov	Pa	Re	Sk	Sp	Te	Ut

Mature sequence

Cmi-Let-7-P2c3_5p

mirBase accession

None

Sequence

0- AGAGGUAGUUGUUUGUACAGUU -22

Get sequence

Star sequence

Cmi-Let-7-P2c3_3p*

mirBase accession

None

Sequence

58- CUGUACAAGCCACUGCCUUGC -79

Get sequence