Let-7-P2a1

MirGeneDB ID

Cmi-Let-7-P2a1

Family name

LET-7 (all species)

Seed

GAGGUAG

Species

Australian ghostshark (Callorhinchus milii)

MiRBase ID

Paralogues

Cmi-Let-7-P1d Cmi-Let-7-P2a2 Cmi-Let-7-P2a4 Cmi-Let-7-P2b2 Cmi-Let-7-P2b4 Cmi-Let-7-P2c1 Cmi-Let-7-P2c2 Cmi-Let-7-P2c3 Cmi-Let-7-P2c4

Orthologues

Aae-Let-7 Aca-Let-7-P2a1 Aga-Let-7 Agr-Let-7 Ami-Let-7-P2a1 Bge-Let-7 Bko-Let-7 Bpl-Let-7 Bta-Let-7-P2a1 Cfa-Let-7-P2a1 Cja-Let-7-P2a1 Cli-Let-7-P2a1 Cpi-Let-7-P2a1 Cpo-Let-7-P2a1 Cte-Let-7 Dan-Let-7 Dlo-Let-7 Dma-Let-7 Dme-Let-7 Dmo-Let-7 Dno-Let-7-P2a1 Dpu-Let-7 Dre-Let-7-P2a1a Dsi-Let-7 Dya-Let-7 Eba-Let-7 Eca-Let-7-P2a1 Egr-Let-7 Esc-Let-7 Ete-Let-7-P2a1 Gga-Let-7-P2a1 Gja-Let-7-P2a1 Gmo-Let-7-P2a1a Gpa-Let-7 Gsa-Let-7 Gsp-Let-7 Hme-Let-7 Hmi-Let-7 Hru-Let-7 Hsa-Let-7-P2a1 Isc-Let-7 Laf-Let-7-P2a1 Lan-Let-7 Lch-Let-7-P2a1 Lgi-Let-7 Lhy-Let-7 Llo-Let-7 Loc-Let-7-P2a1 Mal-Let-7-P2a1a Mdo-Let-7-P2a1 Mgi-Let-7 Mml-Let-7-P2a1 Mmr-Let-7-P2a1 Mmu-Let-7-P2a1 Mom-Let-7 Mun-Let-7-P2a1 Npo-Let-7 Oan-Let-7-P2a1 Obi-Let-7 Ocu-Let-7-P2a1 Ofu-Let-7 Ovu-Let-7 Pab-Let-7-P2a1 Pau-Let-7 Pbv-Let-7-P2a1 Pca-Let-7 Pcr-Let-7 Pdu-Let-7 Pfl-Let-7 Ple-Let-7 Pmi-Let-7 Pve-Let-7 Rno-Let-7-P2a1 Rph-Let-7 Sha-Let-7-P2a1 Sko-Let-7 Sma-Let-7 Sne-Let-7 Snu-Let-7 Spt-Let-7-P2a1 Spu-Let-7 Sro-Let-7 Sto-Let-7-P2a1 Tca-Let-7 Tgu-Let-7-P2a1 Tur-Let-7 War-Let-7 Xbo-Let-7 Xla-Let-7-P2a1c Xla-Let-7-P2a1d Xtr-Let-7-P2a1

Node of Origin (locus)

Gnathostomata

Node of Origin (family)

Bilateria

Genome context
(GCA_000165045.2_Callorhinchus_milii-6.1.3)

KI635961.1: 560380-560450 [-] UCSC Ensembl

Precursor
(pre-Mir +30nt flank)

CUUGCCAAAGAUCCAGUUUGCACUUUGGGAUGAGGUAGUAGGUUGUAUAGUUUUAGGGUCACACCCACACUGGGAGAUAACUAUACAAUCUACUGUCUUUCUUAAGGCUGCACAGUCAUCUUCAACCACUU

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Structure

        10         20         30        40        50        60     
CUUGCCAAAGAUCCAGUU-    -|       U   GU                UUAGGGUCACAC 
                   UGCA CUUUGGGA GAG  AGUAGGUUGUAUAGUU            C
                   ACGU GGAAUUCU UUC  UCAUCUAACAUAUCAA            C
UUCACCAACUUCUACUGAC    C^       -   UG                UAGAGGGUCACA 
 .       120       110       100         90        80        70

Deep sequencing

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Comment

Based on structural and phylogenetic considerations it is assumed that the templated 3' U is a post-transcriptional addition.

3' NTU

Yes

Motifs

CNNC at 3p(+17)

Tissue expression

Bl	Br	Ey	Gi	He	In	Ki	Li	Mu	Ov	Pa	Re	Sk	Sp	Te	Ut

Mature sequence

Cmi-Let-7-P2a1_5p

mirBase accession

None

Sequence

0- UGAGGUAGUAGGUUGUAUAGUU -22

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Star sequence

Cmi-Let-7-P2a1_3p*

mirBase accession

None

Sequence

50- CUAUACAAUCUACUGUCUUUC -71

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