Let-7-P2a1

MirGeneDB ID

Rno-Let-7-P2a1

Family name

LET-7 (all species)

Seed

GAGGUAG

Species

Norway rat (Rattus norvegicus)

MiRBase ID

rno-let-7a-1

Paralogues

Rno-Let-7-P1b Rno-Let-7-P1c Rno-Let-7-P1d Rno-Let-7-P2a2 Rno-Let-7-P2a3 Rno-Let-7-P2b1 Rno-Let-7-P2b2 Rno-Let-7-P2b3 Rno-Let-7-P2c1 Rno-Let-7-P2c2 Rno-Let-7-P2c3

Orthologues

Aae-Let-7 Aca-Let-7-P2a1 Aga-Let-7 Agr-Let-7 Ami-Let-7-P2a1 Bge-Let-7 Bko-Let-7 Bpl-Let-7 Bta-Let-7-P2a1 Cfa-Let-7-P2a1 Cja-Let-7-P2a1 Cli-Let-7-P2a1 Cmi-Let-7-P2a1 Cpi-Let-7-P2a1 Cpo-Let-7-P2a1 Cte-Let-7 Dan-Let-7 Dlo-Let-7 Dma-Let-7 Dme-Let-7 Dmo-Let-7 Dno-Let-7-P2a1 Dpu-Let-7 Dre-Let-7-P2a1a Dsi-Let-7 Dya-Let-7 Eba-Let-7 Eca-Let-7-P2a1 Egr-Let-7 Esc-Let-7 Ete-Let-7-P2a1 Gga-Let-7-P2a1 Gja-Let-7-P2a1 Gmo-Let-7-P2a1a Gpa-Let-7 Gsa-Let-7 Gsp-Let-7 Hme-Let-7 Hmi-Let-7 Hru-Let-7 Hsa-Let-7-P2a1 Isc-Let-7 Laf-Let-7-P2a1 Lan-Let-7 Lch-Let-7-P2a1 Lgi-Let-7 Lhy-Let-7 Llo-Let-7 Loc-Let-7-P2a1 Mal-Let-7-P2a1a Mdo-Let-7-P2a1 Mgi-Let-7 Mml-Let-7-P2a1 Mmr-Let-7-P2a1 Mmu-Let-7-P2a1 Mom-Let-7 Mun-Let-7-P2a1 Npo-Let-7 Oan-Let-7-P2a1 Obi-Let-7 Ocu-Let-7-P2a1 Ofu-Let-7 Ovu-Let-7 Pab-Let-7-P2a1 Pau-Let-7 Pbv-Let-7-P2a1 Pca-Let-7 Pcr-Let-7 Pdu-Let-7 Pfl-Let-7 Ple-Let-7 Pmi-Let-7 Pve-Let-7 Rph-Let-7 Sha-Let-7-P2a1 Sko-Let-7 Sma-Let-7 Sne-Let-7 Snu-Let-7 Spt-Let-7-P2a1 Spu-Let-7 Sro-Let-7 Sto-Let-7-P2a1 Tca-Let-7 Tgu-Let-7-P2a1 Tur-Let-7 War-Let-7 Xbo-Let-7 Xla-Let-7-P2a1c Xla-Let-7-P2a1d Xtr-Let-7-P2a1

Node of Origin (locus)

Gnathostomata

Node of Origin (family)

Bilateria

Genome context
(rn6)

chr17: 16417865-16417936 [+] UCSC Ensembl

Clustered miRNAs
(< 50kb from Let-7-P2a1)

Let-7-P2a1 chr17: 16417865-16417936 [+] UCSC Ensembl
Let-7-P2b1 chr17: 16418228-16418304 [+] UCSC Ensembl
Let-7-P2c1 chr17: 16419993-16420067 [+] UCSC Ensembl

Precursor
(pre-Mir +30nt flank)

UUUGCCCUGGAUGUUGUCUUCACUGUGGGAUGAGGUAGUAGGUUGUAUAGUUUUAGGGUCACACCCACCACUGGGAGAUAACUAUACAAUCUACUGUCUUUCCUAAGGUGAUGGAAAAGUCUGCAUUCGUGG

Get precursor sequence

Structure

        10          20        30        40        50        60      
UUUGCCCUGGAUGUUGU--|U     G     U   GU                UUAGGGUCACACC 
                   C UCACU UGGGA GAG  AGUAGGUUGUAUAGUU             \
                   G AGUGG AUCCU UUC  UCAUCUAACAUAUCAA             C
GGUGCUUACGUCUGAAAAG^U     A     -   UG                UAGAGGGUCACCA 
130       120       110        100        90        80        70

Deep sequencing

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3' NTU

Yes

Motifs

Tissue expression

Dr	Dr	Ad	Bi	Bi	Bi	Bi	Br	Br	Br	Br	Ce	Ce	Ce	Ce	Co	Co	Co	Co	Du	Du	Du	Du	Fa	He	He	He	Hi	Hi	Il	Il	Je	Je	Ki	Ki	Ki	Ki	Ki	La	Li	Li	Li	Li	Li	Li	Lu	Me	Me	Mu	Ov	Pa	Pa	Pa	Sk	Sm	So	So	So	So	Sp	St	St	St	St	Te	Te	Th	Ut	Wh

Mature sequence

Rno-Let-7-P2a1_5p

mirBase accession

MIMAT0000774

Sequence

0- UGAGGUAGUAGGUUGUAUAGUU -22

Get sequence

Proposed targets

microrna.org: MIMAT0000774
TargetScanVert: rno-let-7a-5p
miRDB: MIMAT0000774

Star sequence

Rno-Let-7-P2a1_3p*

mirBase accession

MIMAT0017085

Sequence

51- CUAUACAAUCUACUGUCUUUC -72

Get sequence

Proposed targets

TargetScanVert: rno-let-7a-1-3p
miRDB: MIMAT0017085