Let-7-P1b

MirGeneDB ID

Rno-Let-7-P1b

Family name

LET-7 (all species)

Seed

GAGGUAG

Species

Norway rat (Rattus norvegicus)

MiRBase ID

rno-let-7e

Paralogues

Rno-Let-7-P1c Rno-Let-7-P1d Rno-Let-7-P2a1 Rno-Let-7-P2a2 Rno-Let-7-P2a3 Rno-Let-7-P2b1 Rno-Let-7-P2b2 Rno-Let-7-P2b3 Rno-Let-7-P2c1 Rno-Let-7-P2c2 Rno-Let-7-P2c3

Orthologues

Aae-Let-7 Aca-Let-7-P1b Aga-Let-7 Agr-Let-7 Ami-Let-7-P1b Bge-Let-7 Bko-Let-7 Bpl-Let-7 Bta-Let-7-P1b Cfa-Let-7-P1b Cin-Let-7-P1 Cja-Let-7-P1b Cpi-Let-7-P1b Cpo-Let-7-P1b Cte-Let-7 Dan-Let-7 Dlo-Let-7 Dma-Let-7 Dme-Let-7 Dmo-Let-7 Dpu-Let-7 Dre-Let-7-P1b1 Dre-Let-7-P1b2 Dsi-Let-7 Dya-Let-7 Eba-Let-7 Eca-Let-7-P1b Egr-Let-7 Esc-Let-7 Ete-Let-7-P1b Gja-Let-7-P1b Gmo-Let-7-P1b1 Gmo-Let-7-P1b2 Gpa-Let-7 Gsa-Let-7 Gsp-Let-7 Hme-Let-7 Hmi-Let-7 Hru-Let-7 Hsa-Let-7-P1b Isc-Let-7 Laf-Let-7-P1b Lan-Let-7 Lch-Let-7-P1b Lgi-Let-7 Lhy-Let-7 Llo-Let-7 Loc-Let-7-P1b Mal-Let-7-P1b1 Mal-Let-7-P1b2 Mdo-Let-7-P1b Mgi-Let-7 Mml-Let-7-P1b Mmr-Let-7-P1b Mmu-Let-7-P1b Mom-Let-7 Mun-Let-7-P1b Npo-Let-7 Oan-Let-7-P1b Obi-Let-7 Ocu-Let-7-P1b Ofu-Let-7 Ovu-Let-7 Pab-Let-7-P1b Pau-Let-7 Pbv-Let-7-P1b Pca-Let-7 Pcr-Let-7 Pdu-Let-7 Pfl-Let-7 Ple-Let-7 Pmi-Let-7 Pve-Let-7 Rph-Let-7 Sha-Let-7-P1b Sko-Let-7 Sma-Let-7 Sne-Let-7 Snu-Let-7 Spt-Let-7-P1b Spu-Let-7 Sro-Let-7 Sto-Let-7-P1b Tca-Let-7 Tni-Let-7-P1b1 Tni-Let-7-P1b2 Tur-Let-7 War-Let-7 Xbo-Let-7 Xla-Let-7-P1b3 Xla-Let-7-P1b4 Xtr-Let-7-P1b

Node of Origin (locus)

Gnathostomata

Node of Origin (family)

Bilateria

Genome context
(rn6)

chr1: 59704395-59704461 [+] UCSC Ensembl

Clustered miRNAs
(< 50kb from Let-7-P1b)

Mir-10-P2b chr1: 59704222-59704281 [+] UCSC Ensembl
Let-7-P1b chr1: 59704395-59704461 [+] UCSC Ensembl
Mir-10-P3b chr1: 59704841-59704900 [+] UCSC Ensembl

Precursor
(pre-Mir +30nt flank)

CAAUCUGCCCACCUGCCGCGCCCCCCGGGCUGAGGUAGGAGGUUGUAUAGUUGAGGAAGACACCCGAGGAGAUCACUAUACGGCCUCCUAGCUUUCCCCAGGCUGCGCCCUGCACUGGAAGGGGCCG

Get precursor sequence

Structure

        10          20        30        40        50        60   
CAAUCUGCCCACCUGCC--|   CC  C   CU   G                UGAGGAAGACA 
                   GCGC  CC GGG  GAG UAGGAGGUUGUAUAGU           \
                   CGCG  GG CCC  UUC AUCCUCCGGCAUAUCA           C
GCCGGGGAAGGUCACGUCC^   UC  A   CU   G                CUAGAGGAGCC 
     120       110       100        90        80        70

Deep sequencing

Go to detailed chart

3' NTU

Motifs

Tissue expression

Dr	Dr	Ad	Bi	Bi	Bi	Bi	Br	Br	Br	Br	Ce	Ce	Ce	Ce	Co	Co	Co	Co	Du	Du	Du	Du	Fa	He	He	He	Hi	Hi	Il	Il	Je	Je	Ki	Ki	Ki	Ki	Ki	La	Li	Li	Li	Li	Li	Li	Lu	Me	Me	Mu	Ov	Pa	Pa	Pa	Sk	Sm	So	So	So	So	Sp	St	St	St	St	Te	Te	Th	Ut	Wh

Mature sequence

Rno-Let-7-P1b_5p

mirBase accession

MIMAT0000777

Sequence

0- UGAGGUAGGAGGUUGUAUAGUU -22

Get sequence

Proposed targets

microrna.org: MIMAT0000777
TargetScanVert: rno-let-7e-5p
miRDB: MIMAT0000777

Star sequence

Rno-Let-7-P1b_3p*

mirBase accession

MIMAT0004706

Sequence

45- CUAUACGGCCUCCUAGCUUUCC -67

Get sequence

Proposed targets

microrna.org: MIMAT0004706
TargetScanVert: rno-let-7e-3p
miRDB: MIMAT0004706