Let-7-P2a2

MirGeneDB ID

Rno-Let-7-P2a2

Family name

LET-7 (all species)

Seed

GAGGUAG

Species

Norway rat (Rattus norvegicus)

MiRBase ID

rno-let-7c-2

Paralogues

Rno-Let-7-P1b Rno-Let-7-P1c Rno-Let-7-P1d Rno-Let-7-P2a1 Rno-Let-7-P2a3 Rno-Let-7-P2b1 Rno-Let-7-P2b2 Rno-Let-7-P2b3 Rno-Let-7-P2c1 Rno-Let-7-P2c2 Rno-Let-7-P2c3

Orthologues

Aae-Let-7 Aca-Let-7-P2a2 Aga-Let-7 Agr-Let-7 Ami-Let-7-P2a2 Bge-Let-7 Bko-Let-7 Bpl-Let-7 Bta-Let-7-P2a2 Cfa-Let-7-P2a2 Cja-Let-7-P2a2 Cli-Let-7-P2a2 Cmi-Let-7-P2a2 Cpi-Let-7-P2a2 Cpo-Let-7-P2a2 Cte-Let-7 Dan-Let-7 Dlo-Let-7 Dma-Let-7 Dme-Let-7 Dmo-Let-7 Dno-Let-7-P2a2 Dpu-Let-7 Dre-Let-7-P2a2a Dre-Let-7-P2a2b Dsi-Let-7 Dya-Let-7 Eba-Let-7 Eca-Let-7-P2a2 Egr-Let-7 Esc-Let-7 Ete-Let-7-P2a2 Gga-Let-7-P2a2 Gja-Let-7-P2a2 Gmo-Let-7-P2a2a Gpa-Let-7 Gsa-Let-7 Gsp-Let-7 Hme-Let-7 Hmi-Let-7 Hru-Let-7 Hsa-Let-7-P2a2 Isc-Let-7 Laf-Let-7-P2a2 Lan-Let-7 Lch-Let-7-P2a2 Lgi-Let-7 Lhy-Let-7 Llo-Let-7 Loc-Let-7-P2a2 Mal-Let-7-P2a2a Mal-Let-7-P2a2b Mdo-Let-7-P2a2 Mgi-Let-7 Mml-Let-7-P2a2 Mmr-Let-7-P2a2 Mmu-Let-7-P2a2 Mom-Let-7 Mun-Let-7-P2a2 Neu-Let-7-P2a2 Npo-Let-7 Oan-Let-7-P2a2 Obi-Let-7 Ocu-Let-7-P2a2 Ofu-Let-7 Ovu-Let-7 Pab-Let-7-P2a2 Pau-Let-7 Pbv-Let-7-P2a2 Pca-Let-7 Pcr-Let-7 Pdu-Let-7 Pfl-Let-7 Ple-Let-7 Pmi-Let-7 Pve-Let-7 Rph-Let-7 Sha-Let-7-P2a2 Sko-Let-7 Sma-Let-7 Sne-Let-7 Snu-Let-7 Spt-Let-7-P2a2 Spu-Let-7 Sro-Let-7 Sto-Let-7-P2a2 Tca-Let-7 Tgu-Let-7-P2a2 Tni-Let-7-P2a2a Tni-Let-7-P2a2b Tur-Let-7 War-Let-7 Xbo-Let-7 Xla-Let-7-P2a2c Xla-Let-7-P2a2d Xtr-Let-7-P2a2

Node of Origin (locus)

Gnathostomata

Node of Origin (family)

Bilateria

Genome context
(rn6)

chr7: 126590225-126590293 [+] UCSC Ensembl

Clustered miRNAs
(< 50kb from Let-7-P2a2)

Let-7-P2a2 chr7: 126590225-126590293 [+] UCSC Ensembl
Let-7-P2b2 chr7: 126590633-126590707 [+] UCSC Ensembl

Precursor
(pre-Mir +30nt flank)

UCCGCCAAGACUGACUGACGGCCUUUGGGGUGAGGUAGUAGGUUGUAUGGUUUUGGGCUCUGCCCCGCUCUGCGGUAACUAUACAAUCUACUGUCUUUCCUGAAGUGGCCGCAAUAUCUGCAGUGGAUA

Get precursor sequence

Structure

        10        20         30        40        50        60    
UCCGCCAAGACUGACUGA     -|  G   U   GU                UUGGGCUCUGC 
                  CGGCC UUU GGG GAG  AGUAGGUUGUAUGGUU           C
                  GCCGG GAA UCC UUC  UCAUCUAACAUAUCAA           C
AUAGGUGACGUCUAUAAC     U^  G   U   UG                UGGCGUCUCGC 
       120       110       100        90        80        70

Deep sequencing

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3' NTU

Yes

Motifs

Tissue expression

Dr	Dr	Ad	Bi	Bi	Bi	Bi	Br	Br	Br	Br	Ce	Ce	Ce	Ce	Co	Co	Co	Co	Du	Du	Du	Du	Fa	He	He	He	Hi	Hi	Il	Il	Je	Je	Ki	Ki	Ki	Ki	Ki	La	Li	Li	Li	Li	Li	Li	Lu	Me	Me	Mu	Ov	Pa	Pa	Pa	Sk	Sm	So	So	So	So	Sp	St	St	St	St	Te	Te	Th	Ut	Wh

Mature sequence

Rno-Let-7-P2a2_5p

mirBase accession

MIMAT0000776

Sequence

0- UGAGGUAGUAGGUUGUAUGGUU -22

Get sequence

Proposed targets

microrna.org: MIMAT0000776
TargetScanVert: rno-let-7c-5p
miRDB: MIMAT0000776

Star sequence

Rno-Let-7-P2a2_3p*

mirBase accession

MIMAT0017088

Sequence

48- CUAUACAAUCUACUGUCUUUC -69

Get sequence

Proposed targets

TargetScanVert: rno-let-7c-2-3p
miRDB: MIMAT0017088