Let-7-P2b3

MirGeneDB ID

Rno-Let-7-P2b3

Family name

LET-7 (all species)

Seed

GAGGUAG

Species

Norway rat (Rattus norvegicus)

MiRBase ID

rno-mir-98

Paralogues

Rno-Let-7-P1b Rno-Let-7-P1c Rno-Let-7-P1d Rno-Let-7-P2a1 Rno-Let-7-P2a2 Rno-Let-7-P2a3 Rno-Let-7-P2b1 Rno-Let-7-P2b2 Rno-Let-7-P2c1 Rno-Let-7-P2c2 Rno-Let-7-P2c3

Orthologues

Aae-Let-7 Aca-Let-7-P2b3 Aga-Let-7 Agr-Let-7 Ami-Let-7-P2b3 Bge-Let-7 Bko-Let-7 Bpl-Let-7 Bta-Let-7-P2b3 Cfa-Let-7-P2b3 Cja-Let-7-P2b3 Cpi-Let-7-P2b3 Cpo-Let-7-P2b3 Cte-Let-7 Dan-Let-7 Dlo-Let-7 Dma-Let-7 Dme-Let-7 Dmo-Let-7 Dno-Let-7-P2b3 Dpu-Let-7 Dre-Let-7-P2b3a Dsi-Let-7 Dya-Let-7 Eba-Let-7 Eca-Let-7-P2b3 Egr-Let-7 Esc-Let-7 Ete-Let-7-P2b3 Gja-Let-7-P2b3 Gmo-Let-7-P2b3a Gmo-Let-7-P2b3b Gpa-Let-7 Gsa-Let-7 Gsp-Let-7 Hme-Let-7 Hmi-Let-7 Hru-Let-7 Hsa-Let-7-P2b3 Isc-Let-7 Laf-Let-7-P2b3 Lan-Let-7 Lgi-Let-7 Lhy-Let-7 Llo-Let-7 Loc-Let-7-P2b3 Mal-Let-7-P2b3a Mgi-Let-7 Mml-Let-7-P2b3 Mmr-Let-7-P2b3 Mmu-Let-7-P2b3 Mom-Let-7 Mun-Let-7-P2b3 Npo-Let-7 Oan-Let-7-P2b3 Obi-Let-7 Ocu-Let-7-P2b3 Ofu-Let-7 Ovu-Let-7 Pab-Let-7-P2b3 Pau-Let-7 Pbv-Let-7-P2b3 Pca-Let-7 Pcr-Let-7 Pdu-Let-7 Pfl-Let-7 Ple-Let-7 Pmi-Let-7 Pve-Let-7 Rph-Let-7 Sko-Let-7 Sma-Let-7 Sne-Let-7 Snu-Let-7 Spt-Let-7-P2b3 Spu-Let-7 Sro-Let-7 Sto-Let-7-P2b3 Tca-Let-7 Tni-Let-7-P2b3a Tni-Let-7-P2b3b Tur-Let-7 War-Let-7 Xbo-Let-7 Xla-Let-7-P2b3c Xla-Let-7-P2b3d Xtr-Let-7-P2b3

Node of Origin (locus)

Gnathostomata

Node of Origin (family)

Bilateria

Genome context
(rn6)

chrX: 21583890-21583968 [+] UCSC Ensembl

Clustered miRNAs
(< 50kb from Let-7-P2b3)

Let-7-P2a3 chrX: 21583279-21583349 [+] UCSC Ensembl
Let-7-P2b3 chrX: 21583890-21583968 [+] UCSC Ensembl

Precursor
(pre-Mir +30nt flank)

CCUUACUAGAGACAUCUGCACAUGCUGGGGUGAGGUAGUAAGUUGUAUUGUUGUGGGGUAGGGAUUUUAGGCCCCAAUAAGAAGAUAACUAUACAACUUACUACUUUCCCUGGUGUGUGGCAUACUCACAUUAAGUCUU

Get precursor sequence

Structure

        10          20        30        40        50        60         
CCUUACUAGAGACAUCUG--|      UG   U                 U   GUGGGGUAGGGAUUUU 
                    CACAUGC  GGG GAGGUAGUAAGUUGUAU GUU                A
                    GUGUGUG  CCC UUUCAUCAUUCAACAUA CAA                G
UUCUGAAUUACACUCAUACG^      GU   -                 U   UAGAAGAAUAACCCCG 
       130       120       110        100        90        80        70

Deep sequencing

Go to detailed chart

3' NTU

Yes

Motifs

UG at 5p(-14), UGUG in loop

Tissue expression

Dr	Dr	Ad	Bi	Bi	Bi	Bi	Br	Br	Br	Br	Ce	Ce	Ce	Ce	Co	Co	Co	Co	Du	Du	Du	Du	Fa	He	He	He	Hi	Hi	Il	Il	Je	Je	Ki	Ki	Ki	Ki	Ki	La	Li	Li	Li	Li	Li	Li	Lu	Me	Me	Mu	Ov	Pa	Pa	Pa	Sk	Sm	So	So	So	So	Sp	St	St	St	St	Te	Te	Th	Ut	Wh

Mature sequence

Rno-Let-7-P2b3_5p

mirBase accession

MIMAT0000819

Sequence

0- UGAGGUAGUAAGUUGUAUUGUU -22

Get sequence

Proposed targets

microrna.org: MIMAT0000819
TargetScanVert: rno-miR-98-5p
miRDB: MIMAT0000819

Star sequence

Rno-Let-7-P2b3_3p*

mirBase accession

MIMAT0017111

Sequence

58- CUAUACAACUUACUACUUUCC -79

Get sequence

Proposed targets

TargetScanVert: rno-miR-98-3p
miRDB: MIMAT0017111