10 20 30 40 50 60 70
UUUUUCUCUUUAUACUU- G-| C U UU GUUGGGGAUCAGGAUUG
GGUU UG UG GG GAGGUAGUAAGUUGUGUGUU U
CCGG AC AC CCUUCCGUCAUUCAACAUACAA G
AAGAGAUAUCUACGGUUA AG^ U U - U UAGAGGACUUGCCCCAU
. 130 120 110 100 90 80
Although there is a templated T at the 3' end of the 3p arm, the post-transcriptional addition of a terminal 3' U is supported by the conservation of Let7-P2 processing.