MirGeneDB 3.0
MirGeneDB ID

Hsa-Let-7-P2b3

Family name LET-7 (all species)
Seed GAGGUAG
Species Human (Homo sapiens)
MiRBase ID hsa-mir-98
Paralogues Hsa-Let-7-P1b  Hsa-Let-7-P1c  Hsa-Let-7-P1d  Hsa-Let-7-P2a1  Hsa-Let-7-P2a2  Hsa-Let-7-P2a3  Hsa-Let-7-P2b1  Hsa-Let-7-P2b2  Hsa-Let-7-P2c1  Hsa-Let-7-P2c2  Hsa-Let-7-P2c3 
Orthologues Aae-Let-7  Aca-Let-7-P2b3  Aga-Let-7  Agr-Let-7  Ami-Let-7-P2b3  Bge-Let-7  Bko-Let-7  Bpl-Let-7  Bta-Let-7-P2b3  Cfa-Let-7-P2b3  Cja-Let-7-P2b3  Cpi-Let-7-P2b3  Cpo-Let-7-P2b3  Cte-Let-7  Dan-Let-7  Dlo-Let-7  Dma-Let-7  Dme-Let-7  Dmo-Let-7  Dno-Let-7-P2b3  Dpu-Let-7  Dre-Let-7-P2b3a  Dsi-Let-7  Dya-Let-7  Eba-Let-7  Eca-Let-7-P2b3  Egr-Let-7  Esc-Let-7  Ete-Let-7-P2b3  Gja-Let-7-P2b3  Gmo-Let-7-P2b3a  Gmo-Let-7-P2b3b  Gpa-Let-7  Gsa-Let-7  Gsp-Let-7  Hme-Let-7  Hmi-Let-7  Hru-Let-7  Isc-Let-7  Laf-Let-7-P2b3  Lan-Let-7  Lgi-Let-7  Lhy-Let-7  Llo-Let-7  Loc-Let-7-P2b3  Mal-Let-7-P2b3a  Mgi-Let-7  Mml-Let-7-P2b3  Mmr-Let-7-P2b3  Mmu-Let-7-P2b3  Mom-Let-7  Mun-Let-7-P2b3  Npo-Let-7  Oan-Let-7-P2b3  Obi-Let-7  Ocu-Let-7-P2b3  Ofu-Let-7  Ovu-Let-7  Pab-Let-7-P2b3  Pau-Let-7  Pbv-Let-7-P2b3  Pca-Let-7  Pcr-Let-7  Pdu-Let-7  Pfl-Let-7  Ple-Let-7  Pmi-Let-7  Pve-Let-7  Rno-Let-7-P2b3  Rph-Let-7  Sko-Let-7  Sma-Let-7  Sne-Let-7  Snu-Let-7  Spt-Let-7-P2b3  Spu-Let-7  Sro-Let-7  Sto-Let-7-P2b3  Tca-Let-7  Tni-Let-7-P2b3a  Tni-Let-7-P2b3b  Tur-Let-7  War-Let-7  Xbo-Let-7  Xla-Let-7-P2b3c  Xla-Let-7-P2b3d  Xtr-Let-7-P2b3 
Node of Origin (locus) Gnathostomata
Node of Origin (family) Bilateria
Genome context
(hg38)		 chrX: 53556242-53556320 [-] UCSC Ensembl
Clustered miRNAs
(< 50kb from Let-7-P2b3)		 Let-7-P2b3 chrX: 53556242-53556320 [-] UCSC Ensembl
Let-7-P2a3 chrX: 53557197-53557267 [-] UCSC Ensembl
Precursor
(pre-Mir +30nt flank)
CCUUAUUAGAGGAUUCUGCUCAUGCCAGGGUGAGGUAGUAAGUUGUAUUGUUGUGGGGUAGGGAUAUUAGGCCCCAAUUAGAAGAUAACUAUACAACUUACUACUUUCCCUGGUGUGUGGCAUAUUCACACUUAGUCUU
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Structure
        10         20         30        40        50        60         
CCUUAUUAGAGGAUUCU-   -|         U                 U   GUGGGGUAGGGAUAUU 
                  GCU CAUGCCAGGG GAGGUAGUAAGUUGUAU GUU                A
                  CGG GUGUGGUCCC UUUCAUCAUUCAACAUA CAA                G
UUCUGAUUCACACUUAUA   U^         -                 U   UAGAAGAUUAACCCCG 
       130       120       110        100        90        80        70
Deep sequencing
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3' NTU Yes
MotifsUG at 5p(-14), UGUG in loop
Tissue expression
-   +
Dc Dc Dr Dr Xp Xp Bl Br Br Ce Ce Co Fo He Ki Le Li Li Lu Pa Pl Pl Sk Sk Sk Sm Sp Sp St Te Th Ut
Mature sequence

Hsa-Let-7-P2b3_5p
mirBase accessionMIMAT0000096
Sequence 
0- UGAGGUAGUAAGUUGUAUUGUU -22
Get sequence
Proposed targets microrna.org: MIMAT0000096
TargetScanVert: hsa-miR-98-5p
miRDB: MIMAT0000096
Star sequence

Hsa-Let-7-P2b3_3p*
mirBase accessionMIMAT0022842
Sequence 
58- CUAUACAACUUACUACUUUCC -79
Get sequence
Proposed targets TargetScanVert: hsa-miR-98-3p
miRDB: MIMAT0022842