Let-7-P1b

MirGeneDB ID

Hsa-Let-7-P1b

Family name

LET-7 (all species)

Seed

GAGGUAG

Species

Human (Homo sapiens)

MiRBase ID

hsa-let-7e

Paralogues

Hsa-Let-7-P1c Hsa-Let-7-P1d Hsa-Let-7-P2a1 Hsa-Let-7-P2a2 Hsa-Let-7-P2a3 Hsa-Let-7-P2b1 Hsa-Let-7-P2b2 Hsa-Let-7-P2b3 Hsa-Let-7-P2c1 Hsa-Let-7-P2c2 Hsa-Let-7-P2c3

Orthologues

Aae-Let-7 Aca-Let-7-P1b Ami-Let-7-P1b Bge-Let-7 Bpl-Let-7 Bta-Let-7-P1b Cfa-Let-7-P1b Cgi-Let-7 Cin-Let-7-P1 Cpi-Let-7-P1b Cpo-Let-7-P1b Cte-Let-7 Dan-Let-7 Dma-Let-7 Dme-Let-7 Dmo-Let-7 Dpu-Let-7 Dre-Let-7-P1b1 Dre-Let-7-P1b2 Dsi-Let-7 Dya-Let-7 Esc-Let-7 Ete-Let-7-P1b Gja-Let-7-P1b Gmo-Let-7-P1b1 Gmo-Let-7-P1b2 Hme-Let-7 Isc-Let-7 Lan-Let-7 Lch-Let-7-P1b Lgi-Let-7 Loc-Let-7-P1b Mal-Let-7-P1b1 Mal-Let-7-P1b2 Mdo-Let-7-P1b Mml-Let-7-P1b Mmu-Let-7-P1b Mun-Let-7-P1b Npo-Let-7 Oan-Let-7-P1b Obi-Let-7 Ocu-Let-7-P1b Ovu-Let-7 Pbv-Let-7-P1b Pfl-Let-7 Pmi-Let-7 Rno-Let-7-P1b Sha-Let-7-P1b Sko-Let-7 Spt-Let-7-P1b Spu-Let-7 Sto-Let-7-P1b Tca-Let-7 Tni-Let-7-P1b1 Tni-Let-7-P1b2 Xbo-Let-7 Xla-Let-7-P1b3 Xla-Let-7-P1b4 Xtr-Let-7-P1b

Node of Origin (locus)

Gnathostomata

Node of Origin (family)

Bilateria

Genome context
(hg38)

chr19: 51692793-51692859 [+] UCSC Ensembl

Clustered miRNAs
(< 50kb from Let-7-P1b)

Mir-10-P2b chr19: 51692618-51692677 [+] UCSC Ensembl
Let-7-P1b chr19: 51692793-51692859 [+] UCSC Ensembl
Mir-10-P3b chr19: 51693268-51693327 [+] UCSC Ensembl

Precursor
(pre-Mir +30nt flank)

GGGUCUGUCCACCUGCCGCGCCCCCCGGGCUGAGGUAGGAGGUUGUAUAGUUGAGGAGGACACCCAAGGAGAUCACUAUACGGCCUCCUAGCUUUCCCCAGGCUGCGCCCUGCACGGGACGGGGCCC

Get precursor sequence

Structure

        10          20        30        40        50        60   
GGGUCUGUCCACCUGCC--|   CC  C   CU   G                UGAGGAGGACA 
                   GCGC  CC GGG  GAG UAGGAGGUUGUAUAGU           \
                   CGCG  GG CCC  UUC AUCCUCCGGCAUAUCA           C
CCCGGGGCAGGGCACGUCC^   UC  A   CU   G                CUAGAGGAACC 
     120       110       100        90        80        70

Deep sequencing

Go to detailed chart

3' NTU

Motifs

Tissue expression

1-	1-	1-	1-	1-	1-	1-	1-	1-	1-	1-	1-	1-	2-	2-	2-	2-	2-	2-	2-	2-	2-	2-	2-	3-	3-	3-	4-	4-	4-	4-	4-	4-	4-	4-	4-	4-	4-	4-	4-	4-	4-	4-	4-	4-	5-	5-	5-	5-	5-	5-	5-	6-	6-	6-	6-	6-

Mature sequence

Hsa-Let-7-P1b_5p

mirBase accession

MIMAT0000066

Sequence

0- UGAGGUAGGAGGUUGUAUAGUU -22

Get sequence

Proposed targets

microrna.org: MIMAT0000066
TargetScanVert: hsa-let-7e-5p
TargetMiner: hsa-let-7e-5p
miRDB: MIMAT0000066

Star sequence

Hsa-Let-7-P1b_3p*

mirBase accession

MIMAT0004485

Sequence

45- CUAUACGGCCUCCUAGCUUUCC -67

Get sequence

Proposed targets

microrna.org: MIMAT0004485
TargetScanVert: hsa-let-7e-3p
TargetMiner: hsa-let-7e-3p
miRDB: MIMAT0004485