Let-7-P1

MirGeneDB ID

Cin-Let-7-P1

Family name

LET-7 (all species)

Seed

GAGGUAG

Species

Sea Squirt (Ciona intestinalis)

MiRBase ID

cin-let-7d

Paralogues

Cin-Let-7-P2o1-v1 Cin-Let-7-P2o1-v2 Cin-Let-7-P2o2 Cin-Let-7-P2o3 Cin-Let-7-P2o4 Cin-Let-7-P2o5

Orthologues

Aae-Let-7 Aca-Let-7-P1b Aca-Let-7-P1c Aca-Let-7-P1d Aga-Let-7 Agr-Let-7 Ami-Let-7-P1b Ami-Let-7-P1c Ami-Let-7-P1d Bge-Let-7 Bko-Let-7 Bpl-Let-7 Bta-Let-7-P1b Bta-Let-7-P1c Bta-Let-7-P1d Cfa-Let-7-P1b Cfa-Let-7-P1c Cfa-Let-7-P1d Cja-Let-7-P1b Cja-Let-7-P1c Cja-Let-7-P1d Cli-Let-7-P1c Cli-Let-7-P1d Cmi-Let-7-P1d Cpi-Let-7-P1b Cpi-Let-7-P1c Cpi-Let-7-P1d Cpo-Let-7-P1b Cpo-Let-7-P1c Cpo-Let-7-P1d Cte-Let-7 Dan-Let-7 Dlo-Let-7 Dma-Let-7 Dme-Let-7 Dmo-Let-7 Dno-Let-7-P1c Dno-Let-7-P1d Dpu-Let-7 Dre-Let-7-P1b1 Dre-Let-7-P1b2 Dre-Let-7-P1c1 Dre-Let-7-P1c2 Dre-Let-7-P1d1 Dre-Let-7-P1d2 Dsi-Let-7 Dya-Let-7 Eba-Let-7 Ebu-Let-7-P1e Eca-Let-7-P1b Eca-Let-7-P1c Eca-Let-7-P1d Egr-Let-7 Esc-Let-7 Ete-Let-7-P1b Ete-Let-7-P1c Ete-Let-7-P1d Gga-Let-7-P1c Gga-Let-7-P1d Gja-Let-7-P1b Gja-Let-7-P1c Gja-Let-7-P1d Gmo-Let-7-P1b1 Gmo-Let-7-P1b2 Gmo-Let-7-P1c2 Gmo-Let-7-P1d1 Gmo-Let-7-P1d2 Gpa-Let-7 Gsa-Let-7 Gsp-Let-7 Hme-Let-7 Hmi-Let-7 Hru-Let-7 Hsa-Let-7-P1b Hsa-Let-7-P1c Hsa-Let-7-P1d Isc-Let-7 Laf-Let-7-P1b Laf-Let-7-P1c Laf-Let-7-P1d Lan-Let-7 Lch-Let-7-P1b Lch-Let-7-P1c Lch-Let-7-P1d Lgi-Let-7 Lhy-Let-7 Llo-Let-7 Loc-Let-7-P1b Loc-Let-7-P1c Loc-Let-7-P1d Mal-Let-7-P1b1 Mal-Let-7-P1b2 Mal-Let-7-P1c2 Mal-Let-7-P1d1 Mal-Let-7-P1d2 Mdo-Let-7-P1b Mdo-Let-7-P1d Mgi-Let-7 Mml-Let-7-P1b Mml-Let-7-P1c Mml-Let-7-P1d Mmr-Let-7-P1b Mmr-Let-7-P1c Mmr-Let-7-P1d Mmu-Let-7-P1b Mmu-Let-7-P1c Mmu-Let-7-P1d Mom-Let-7 Mun-Let-7-P1b Mun-Let-7-P1c Mun-Let-7-P1d Neu-Let-7-P1c Neu-Let-7-P1d Npo-Let-7 Oan-Let-7-P1b Oan-Let-7-P1c Oan-Let-7-P1d Obi-Let-7 Ocu-Let-7-P1b Ocu-Let-7-P1c Ocu-Let-7-P1d Ofu-Let-7 Ovu-Let-7 Pab-Let-7-P1b Pab-Let-7-P1c Pab-Let-7-P1d Pau-Let-7 Pbv-Let-7-P1b Pbv-Let-7-P1c Pbv-Let-7-P1d Pca-Let-7 Pcr-Let-7 Pdu-Let-7 Pfl-Let-7 Ple-Let-7 Pma-Let-7-P1o1 Pmi-Let-7 Pve-Let-7 Rno-Let-7-P1b Rno-Let-7-P1c Rno-Let-7-P1d Rph-Let-7 Sha-Let-7-P1b Sha-Let-7-P1c Sha-Let-7-P1d Sko-Let-7 Sma-Let-7 Sne-Let-7 Snu-Let-7 Spt-Let-7-P1b Spt-Let-7-P1c Spt-Let-7-P1d Spu-Let-7 Sro-Let-7 Sto-Let-7-P1b Sto-Let-7-P1c Sto-Let-7-P1d Tca-Let-7 Tgu-Let-7-P1c Tgu-Let-7-P1d Tni-Let-7-P1b1 Tni-Let-7-P1b2 Tni-Let-7-P1d1 Tni-Let-7-P1d2 Tur-Let-7 War-Let-7 Xbo-Let-7 Xla-Let-7-P1b3 Xla-Let-7-P1b4 Xla-Let-7-P1c3 Xla-Let-7-P1c4 Xtr-Let-7-P1b Xtr-Let-7-P1c

Node of Origin (locus)

Olfactores

Node of Origin (family)

Bilateria

Genome context
(ci3)

10: 1022546-1022607 [-] UCSC Ensembl

Clustered miRNAs
(< 50kb from Let-7-P1)

Mir-10-P3 10: 1022411-1022462 [-] UCSC Ensembl
Let-7-P1 10: 1022546-1022607 [-] UCSC Ensembl
Mir-10-P2 10: 1023005-1023063 [-] UCSC Ensembl

Precursor
(pre-Mir +30nt flank)

AAAAAAAGACAUUUGUCAGCUAUUCGUGGCUGAGGUAGUUGGUUGUAUUGUUUCCCUUGUGUAAUGUUAACUAUACAGCCCGCUAGCUUAACCAUGGUUGCUAACUAUCCACGAAUAAAAGC

Get precursor sequence

Structure

        10           20        30        40        50        60
AAAAAAAGACAUUUGUC---|  UAU      C    G    U        U   UCCCUUG 
                    AGC   UCGUGG UGAG UAGU GGUUGUAU GUU       U
                    UCG   GGUACC AUUC AUCG CCGACAUA CAA       G
CGAAAAUAAGCACCUAUCAA^  UU-      A    G    C        U   UUGUAAU 
120       110       100         90        80        70

Deep sequencing

Go to detailed chart

3' NTU

Motifs

CNNC at 3p(+17)

Tissue expression

C-	C-	C-	C-	C-	C-	C-	C-	C-	C-	Ga	La	La

Mature sequence

Cin-Let-7-P1_5p

mirBase accession

MIMAT0006089

Sequence

0- UGAGGUAGUUGGUUGUAUUGUU -22

Get sequence

Star sequence

Cin-Let-7-P1_3p*

mirBase accession

MIMAT0015250

Sequence

40- CUAUACAGCCCGCUAGCUUAAC -62

Get sequence