Let-7-P1c

MirGeneDB ID

Bta-Let-7-P1c

Family name

LET-7 (all species)

Seed

GAGGUAG

Species

Cow (Bos taurus)

MiRBase ID

bta-let-7c

Paralogues

Bta-Let-7-P1b Bta-Let-7-P1d Bta-Let-7-P2a1 Bta-Let-7-P2a2 Bta-Let-7-P2a3 Bta-Let-7-P2b1 Bta-Let-7-P2b2 Bta-Let-7-P2b3 Bta-Let-7-P2c1 Bta-Let-7-P2c2 Bta-Let-7-P2c3

Orthologues

Aae-Let-7 Aca-Let-7-P1c Aga-Let-7 Agr-Let-7 Ami-Let-7-P1c Bge-Let-7 Bko-Let-7 Bpl-Let-7 Cfa-Let-7-P1c Cin-Let-7-P1 Cja-Let-7-P1c Cli-Let-7-P1c Cpi-Let-7-P1c Cpo-Let-7-P1c Cte-Let-7 Dan-Let-7 Dlo-Let-7 Dma-Let-7 Dme-Let-7 Dmo-Let-7 Dno-Let-7-P1c Dpu-Let-7 Dre-Let-7-P1c1 Dre-Let-7-P1c2 Dsi-Let-7 Dya-Let-7 Eba-Let-7 Eca-Let-7-P1c Egr-Let-7 Esc-Let-7 Ete-Let-7-P1c Gga-Let-7-P1c Gja-Let-7-P1c Gmo-Let-7-P1c2 Gpa-Let-7 Gsa-Let-7 Gsp-Let-7 Hme-Let-7 Hmi-Let-7 Hru-Let-7 Hsa-Let-7-P1c Isc-Let-7 Laf-Let-7-P1c Lan-Let-7 Lch-Let-7-P1c Lgi-Let-7 Lhy-Let-7 Llo-Let-7 Loc-Let-7-P1c Mal-Let-7-P1c2 Mgi-Let-7 Mml-Let-7-P1c Mmr-Let-7-P1c Mmu-Let-7-P1c Mom-Let-7 Mun-Let-7-P1c Neu-Let-7-P1c Npo-Let-7 Oan-Let-7-P1c Obi-Let-7 Ocu-Let-7-P1c Ofu-Let-7 Ovu-Let-7 Pab-Let-7-P1c Pau-Let-7 Pbv-Let-7-P1c Pca-Let-7 Pcr-Let-7 Pdu-Let-7 Pfl-Let-7 Ple-Let-7 Pmi-Let-7 Pve-Let-7 Rno-Let-7-P1c Rph-Let-7 Sha-Let-7-P1c Sko-Let-7 Sma-Let-7 Sne-Let-7 Snu-Let-7 Spt-Let-7-P1c Spu-Let-7 Sro-Let-7 Sto-Let-7-P1c Tca-Let-7 Tgu-Let-7-P1c Tur-Let-7 War-Let-7 Xbo-Let-7 Xla-Let-7-P1c3 Xla-Let-7-P1c4 Xtr-Let-7-P1c

Node of Origin (locus)

Gnathostomata

Node of Origin (family)

Bilateria

Genome context
(GCF_002263795.1_ARS-UCD1.2_BTA)

NC_037328.1: 20434624-20434690 [-] UCSC Ensembl

Clustered miRNAs
(< 50kb from Let-7-P1c)

Mir-10-P3c NC_037328.1: 20385513-20385573 [-] UCSC Ensembl
Let-7-P1c NC_037328.1: 20434624-20434690 [-] UCSC Ensembl
Mir-10-P2c NC_037328.1: 20435353-20435411 [-] UCSC Ensembl

Precursor
(pre-Mir +30nt flank)

AGCAACACUGGAAGCUGUGUGCAUCCGGGUUGAGGUAGUAGGUUGUAUGGUUUAGAGUUACACCCUGGGAGUUAACUGUACAACCUUCUAGCUUUCCUUGGAGCACACUUGAGCCAUCGAGGAAUUC

Get precursor sequence

Structure

        10           20        30        40        50        60   
AGCAACACUGGAAGCUG---|    A      UU   G   U             UAGAGUUACA 
                    UGUGC UCCGGG  GAG UAG AGGUUGUAUGGUU          \
                    ACACG AGGUUC  UUC AUC UCCAACAUGUCAA          C
CUUAAGGAGCUACCGAGUUC^    -      CU   G   U             UUGAGGGUCC 
     120       110        100        90        80        70

Deep sequencing

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3' NTU

Motifs

CNNC at 3p(+17)

Tissue expression

Ad	Bo	Br	Ce	Co	Co	De	Fe	He	Hy	Ir	Ki	La	Lo	Mi	No	Op	Or	Pe	Re	Su	Te

Mature sequence

Bta-Let-7-P1c_5p

mirBase accession

MIMAT0004332

Sequence

0- UGAGGUAGUAGGUUGUAUGGUU -22

Get sequence

Proposed targets

TargetScanVert: bta-let-7c

Star sequence

Bta-Let-7-P1c_3p*

mirBase accession

None

Sequence

45- CUGUACAACCUUCUAGCUUUCC -67

Get sequence