Let-7-P2b1

MirGeneDB ID

Bta-Let-7-P2b1

Family name

LET-7 (all species)

Seed

GAGGUAG

Species

Cow (Bos taurus)

MiRBase ID

bta-let-7f-1

Paralogues

Bta-Let-7-P1b Bta-Let-7-P1c Bta-Let-7-P1d Bta-Let-7-P2a1 Bta-Let-7-P2a2 Bta-Let-7-P2a3 Bta-Let-7-P2b2 Bta-Let-7-P2b3 Bta-Let-7-P2c1 Bta-Let-7-P2c2 Bta-Let-7-P2c3

Orthologues

Aae-Let-7 Aca-Let-7-P2b1 Ami-Let-7-P2b1 Bge-Let-7 Bpl-Let-7 Cfa-Let-7-P2b1 Cgi-Let-7 Cli-Let-7-P2b1 Cpi-Let-7-P2b1 Cpo-Let-7-P2b1 Cte-Let-7 Dan-Let-7 Dma-Let-7 Dme-Let-7 Dmo-Let-7 Dno-Let-7-P2b1 Dpu-Let-7 Dre-Let-7-P2b1a Dsi-Let-7 Dya-Let-7 Esc-Let-7 Ete-Let-7-P2b1 Gga-Let-7-P2b1 Gja-Let-7-P2b1 Gmo-Let-7-P2b1a Hme-Let-7 Hsa-Let-7-P2b1 Isc-Let-7 Lan-Let-7 Lch-Let-7-P2b1 Lgi-Let-7 Loc-Let-7-P2b1 Mal-Let-7-P2b1a Mdo-Let-7-P2b1 Mml-Let-7-P2b1 Mmu-Let-7-P2b1 Mun-Let-7-P2b1 Npo-Let-7 Oan-Let-7-P2b1 Obi-Let-7 Ocu-Let-7-P2b1 Ovu-Let-7 Pbv-Let-7-P2b1 Pfl-Let-7 Pmi-Let-7 Rno-Let-7-P2b1 Sha-Let-7-P2b1 Sko-Let-7 Spt-Let-7-P2b1 Spu-Let-7 Tca-Let-7 Tgu-Let-7-P2b1 Xbo-Let-7

Node of Origin (locus)

Gnathostomata

Node of Origin (family)

Bilateria

Genome context
(GCF_002263795.1_ARS-UCD1.2_BTA)

NC_037335.1: 85450756-85450832 [+] UCSC Ensembl

Clustered miRNAs
(< 50kb from Let-7-P2b1)

Let-7-P2a1 NC_037335.1: 85450402-85450473 [+] UCSC Ensembl
Let-7-P2b1 NC_037335.1: 85450756-85450832 [+] UCSC Ensembl
Let-7-P2c1 NC_037335.1: 85452964-85453038 [+] UCSC Ensembl

Precursor
(pre-Mir +30nt flank)

AUUUCAGAAGAAAAGAUUGCUCUAUCAGAGUGAGGUAGUAGAUUGUAUAGUUGUGGGGUAGUGAUUUUACCCUGUUCAGGAGAUAACUAUACAAUCUAUUGCCUUCCCUGAGGAGUAGACUUGCUGCAUUUUGUUUU

Get precursor sequence

Structure

        10           20        30        40        50        60        
AUUUCAGAAGAAAAGAU---|     A    AGU                     GUGGGGUAGUGAUUU 
                    UGCUCU UCAG   GAGGUAGUAGAUUGUAUAGUU               U
                    AUGAGG AGUC   UUCCGUUAUCUAACAUAUCAA               A
UUUUGUUUUACGUCGUUCAG^     -    CC-                     UAGAGGACUUGUCCC 
     130       120        110        100        90        80        70

Deep sequencing

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3' NTU

Yes

Motifs

CNNC at 3p(+17), UGUG in loop

Tissue expression

Ad	Cd	Fe	Bo	Br	Ce	Co	Co	De	He	Hy	Ir	Ki	La	Lo	No	Op	Or	Pe	Re	Su	Te

Mature sequence

Bta-Let-7-P2b1_5p

mirBase accession

MIMAT0003519

Sequence

0- UGAGGUAGUAGAUUGUAUAGUU -22

Get sequence

Proposed targets

TargetScanVert: bta-let-7f

Star sequence

Bta-Let-7-P2b1_3p*

mirBase accession

None

Sequence

56- CUAUACAAUCUAUUGCCUUCC -77

Get sequence