Let-7-P2b1

MirGeneDB ID

Gga-Let-7-P2b1

Family name

LET-7 (all species)

Seed

GAGGUAG

Species

Chicken (Gallus gallus)

MiRBase ID

gga-let-7f

Paralogues

Gga-Let-7-P1c Gga-Let-7-P1d Gga-Let-7-P2a1 Gga-Let-7-P2a2 Gga-Let-7-P2a4 Gga-Let-7-P2b2 Gga-Let-7-P2b4 Gga-Let-7-P2c1 Gga-Let-7-P2c2 Gga-Let-7-P2c3

Orthologues

Aae-Let-7 Aca-Let-7-P2b1 Aga-Let-7 Agr-Let-7 Ami-Let-7-P2b1 Bge-Let-7 Bko-Let-7 Bpl-Let-7 Bta-Let-7-P2b1 Cfa-Let-7-P2b1 Cja-Let-7-P2b1 Cli-Let-7-P2b1 Cpi-Let-7-P2b1 Cpo-Let-7-P2b1 Cte-Let-7 Dan-Let-7 Dlo-Let-7 Dma-Let-7 Dme-Let-7 Dmo-Let-7 Dno-Let-7-P2b1 Dpu-Let-7 Dre-Let-7-P2b1a Dsi-Let-7 Dya-Let-7 Eba-Let-7 Eca-Let-7-P2b1 Egr-Let-7 Esc-Let-7 Ete-Let-7-P2b1 Gja-Let-7-P2b1 Gmo-Let-7-P2b1a Gpa-Let-7 Gsa-Let-7 Gsp-Let-7 Hme-Let-7 Hmi-Let-7 Hru-Let-7 Hsa-Let-7-P2b1 Isc-Let-7 Laf-Let-7-P2b1 Lan-Let-7 Lch-Let-7-P2b1 Lgi-Let-7 Lhy-Let-7 Llo-Let-7 Loc-Let-7-P2b1 Mal-Let-7-P2b1a Mdo-Let-7-P2b1 Mgi-Let-7 Mml-Let-7-P2b1 Mmr-Let-7-P2b1 Mmu-Let-7-P2b1 Mom-Let-7 Mun-Let-7-P2b1 Neu-Let-7-P2b1 Npo-Let-7 Oan-Let-7-P2b1 Obi-Let-7 Ocu-Let-7-P2b1 Ofu-Let-7 Ovu-Let-7 Pab-Let-7-P2b1 Pau-Let-7 Pbv-Let-7-P2b1 Pca-Let-7 Pcr-Let-7 Pdu-Let-7 Pfl-Let-7 Ple-Let-7 Pmi-Let-7 Pve-Let-7 Rno-Let-7-P2b1 Rph-Let-7 Sha-Let-7-P2b1 Sko-Let-7 Sma-Let-7 Sne-Let-7 Snu-Let-7 Spt-Let-7-P2b1 Spu-Let-7 Sro-Let-7 Tca-Let-7 Tgu-Let-7-P2b1 Tur-Let-7 War-Let-7 Xbo-Let-7

Node of Origin (locus)

Gnathostomata

Node of Origin (family)

Bilateria

Genome context
(Gallus_gallus.GRCg6a)

12: 6489795-6489871 [-] UCSC Ensembl

Clustered miRNAs
(< 50kb from Let-7-P2b1)

Let-7-P2c1 12: 6488759-6488833 [-] UCSC Ensembl
Let-7-P2b1 12: 6489795-6489871 [-] UCSC Ensembl
Let-7-P2a1 12: 6490211-6490282 [-] UCSC Ensembl

Precursor
(pre-Mir +30nt flank)

AGAGCUUAAGUACAUGCUUCUCUGUCAGAGUGAGGUAGUAGAUUGUAUAGUUGUAGGGUAGUUAUUUUACCCUGUUCAGGAGAUAACUAUACAAUCUAUUGCCUUCCCUGAGGAGUAAAACAAACUGCGGUCCUUUG

Get precursor sequence

Structure

        10           20        30        40        50        60        
AGAGCUUAAGUACAUGCUU---|   G    AGU                     GUAGGGUAGUUAUUU 
                      CUCU UCAG   GAGGUAGUAGAUUGUAUAGUU               U
                      GAGG AGUC   UUCCGUUAUCUAACAUAUCAA               A
GUUUCCUGGCGUCAAACAAAAU^   -    CC-                     UAGAGGACUUGUCCC 
     130       120        110        100        90        80        70

Deep sequencing

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3' NTU

Yes

Motifs

CNNC at 3p(+17)

Tissue expression

Ad	Ad	Ad	Br	Br	Ce	Ce	Ce	Ce	Gg	He	He	Hy	Hy	Ki	Ki	Li	Li	Lu	Lu	Ov	Pr	Pr	Sc	Sc	Sp	Sp	Te

Mature sequence

Gga-Let-7-P2b1_5p

mirBase accession

MIMAT0001162

Sequence

0- UGAGGUAGUAGAUUGUAUAGUU -22

Get sequence

Proposed targets

TargetScanVert: gga-let-7f-5p
miRDB: MIMAT0001162

Star sequence

Gga-Let-7-P2b1_3p*

mirBase accession

MIMAT0026528

Sequence

56- CUAUACAAUCUAUUGCCUUCC -77

Get sequence

Proposed targets

TargetScanVert: gga-let-7f-3p
miRDB: MIMAT0026528