Let-7-P2a4

MirGeneDB ID

Gga-Let-7-P2a4

Family name

LET-7 (all species)

Seed

GAGGUAG

Species

Chicken (Gallus gallus)

MiRBase ID

gga-let-7k

Paralogues

Gga-Let-7-P1c Gga-Let-7-P1d Gga-Let-7-P2a1 Gga-Let-7-P2a2 Gga-Let-7-P2b1 Gga-Let-7-P2b2 Gga-Let-7-P2b4 Gga-Let-7-P2c1 Gga-Let-7-P2c2 Gga-Let-7-P2c3

Orthologues

Aae-Let-7 Aca-Let-7-P2a4 Aga-Let-7 Agr-Let-7 Ami-Let-7-P2a4 Bge-Let-7 Bko-Let-7 Bpl-Let-7 Cli-Let-7-P2a4 Cmi-Let-7-P2a4 Cpi-Let-7-P2a4 Cte-Let-7 Dan-Let-7 Dlo-Let-7 Dma-Let-7 Dme-Let-7 Dmo-Let-7 Dpu-Let-7 Dre-Let-7-P2a4a Dre-Let-7-P2a4b Dsi-Let-7 Dya-Let-7 Eba-Let-7 Egr-Let-7 Esc-Let-7 Gja-Let-7-P2a4 Gmo-Let-7-P2a4a Gmo-Let-7-P2a4b Gpa-Let-7 Gsa-Let-7 Gsp-Let-7 Hme-Let-7 Hmi-Let-7 Hru-Let-7 Isc-Let-7 Lan-Let-7 Lch-Let-7-P2a4 Lgi-Let-7 Lhy-Let-7 Llo-Let-7 Loc-Let-7-P2a4 Mal-Let-7-P2a4a Mal-Let-7-P2a4b Mgi-Let-7 Mom-Let-7 Mun-Let-7-P2a4 Npo-Let-7 Oan-Let-7-P2a4 Obi-Let-7 Ofu-Let-7 Ovu-Let-7 Pau-Let-7 Pbv-Let-7-P2a4 Pca-Let-7 Pcr-Let-7 Pdu-Let-7 Pfl-Let-7 Ple-Let-7 Pmi-Let-7 Pve-Let-7 Rph-Let-7 Sko-Let-7 Sma-Let-7 Sne-Let-7 Snu-Let-7 Spt-Let-7-P2a4 Spu-Let-7 Sro-Let-7 Tca-Let-7 Tgu-Let-7-P2a4 Tni-Let-7-P2a4a Tni-Let-7-P2a4b Tur-Let-7 War-Let-7 Xbo-Let-7

Node of Origin (locus)

Gnathostomata

Node of Origin (family)

Bilateria

Genome context
(Gallus_gallus.GRCg6a)

26: 1650925-1650995 [-] UCSC Ensembl

Clustered miRNAs
(< 50kb from Let-7-P2a4)

Let-7-P2b4 26: 1650720-1650797 [-] UCSC Ensembl
Let-7-P2a4 26: 1650925-1650995 [-] UCSC Ensembl

Precursor
(pre-Mir +30nt flank)

AUGGCAAUGGUCCCAAGCUGUCCUUGAGGCUGAGGUAGUAGAUUGAAUAGUUGUGGAGUCCUAUCCUCCCUUUGAGCUAACUAUACAAUCUACUGUCUUUCCUAAGGAGACAGUCAGAUCUUCAGUUCGUC

Get precursor sequence

Structure

        10         20         30        40        50        60     
AUGGCAAUGGUCCCAAG-     -|  G   CU   GU         A      GUGGAGUCCUAU 
                  CUGUC CUU AGG  GAG  AGUAGAUUG AUAGUU            C
                  GACAG GGA UCC  UUC  UCAUCUAAC UAUCAA            C
CUGCUUGACUUCUAGACU     A^  A   U-   UG         A      UCGAGUUUCCCU 
 .       120       110       100         90        80        70

Deep sequencing

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3' NTU

Yes

Motifs

UGUG in loop

Tissue expression

Ad	Ad	Ad	Br	Br	Ce	Ce	Ce	Ce	Gg	He	He	Hy	Hy	Ki	Ki	Li	Li	Lu	Lu	Ov	Pr	Pr	Sc	Sc	Sp	Sp	Te

Mature sequence

Gga-Let-7-P2a4_5p

mirBase accession

MIMAT0001182

Sequence

0- UGAGGUAGUAGAUUGAAUAGUU -22

Get sequence

Proposed targets

TargetScanVert: gga-let-7k-5p
miRDB: MIMAT0001182

Star sequence

Gga-Let-7-P2a4_3p*

mirBase accession

MIMAT0026543

Sequence

50- CUAUACAAUCUACUGUCUUUC -71

Get sequence

Proposed targets

TargetScanVert: gga-let-7k-3p
miRDB: MIMAT0026543