MirGeneDB 3.0
MirGeneDB ID

Rno-Let-7-P2b1

Family name LET-7 (all species)
Seed GAGGUAG
Species Norway rat (Rattus norvegicus)
MiRBase ID rno-let-7f-1
Paralogues Rno-Let-7-P1b  Rno-Let-7-P1c  Rno-Let-7-P1d  Rno-Let-7-P2a1  Rno-Let-7-P2a2  Rno-Let-7-P2a3  Rno-Let-7-P2b2  Rno-Let-7-P2b3  Rno-Let-7-P2c1  Rno-Let-7-P2c2  Rno-Let-7-P2c3 
Orthologues Aae-Let-7  Aca-Let-7-P2b1  Aga-Let-7  Agr-Let-7  Ami-Let-7-P2b1  Bge-Let-7  Bko-Let-7  Bpl-Let-7  Bta-Let-7-P2b1  Cfa-Let-7-P2b1  Cja-Let-7-P2b1  Cli-Let-7-P2b1  Cpi-Let-7-P2b1  Cpo-Let-7-P2b1  Cte-Let-7  Dan-Let-7  Dlo-Let-7  Dma-Let-7  Dme-Let-7  Dmo-Let-7  Dno-Let-7-P2b1  Dpu-Let-7  Dre-Let-7-P2b1a  Dsi-Let-7  Dya-Let-7  Eba-Let-7  Eca-Let-7-P2b1  Egr-Let-7  Esc-Let-7  Ete-Let-7-P2b1  Gga-Let-7-P2b1  Gja-Let-7-P2b1  Gmo-Let-7-P2b1a  Gpa-Let-7  Gsa-Let-7  Gsp-Let-7  Hme-Let-7  Hmi-Let-7  Hru-Let-7  Hsa-Let-7-P2b1  Isc-Let-7  Laf-Let-7-P2b1  Lan-Let-7  Lch-Let-7-P2b1  Lgi-Let-7  Lhy-Let-7  Llo-Let-7  Loc-Let-7-P2b1  Mal-Let-7-P2b1a  Mdo-Let-7-P2b1  Mgi-Let-7  Mml-Let-7-P2b1  Mmr-Let-7-P2b1  Mmu-Let-7-P2b1  Mom-Let-7  Mun-Let-7-P2b1  Neu-Let-7-P2b1  Npo-Let-7  Oan-Let-7-P2b1  Obi-Let-7  Ocu-Let-7-P2b1  Ofu-Let-7  Ovu-Let-7  Pab-Let-7-P2b1  Pau-Let-7  Pbv-Let-7-P2b1  Pca-Let-7  Pcr-Let-7  Pdu-Let-7  Pfl-Let-7  Ple-Let-7  Pmi-Let-7  Pve-Let-7  Rph-Let-7  Sha-Let-7-P2b1  Sko-Let-7  Sma-Let-7  Sne-Let-7  Snu-Let-7  Spt-Let-7-P2b1  Spu-Let-7  Sro-Let-7  Tca-Let-7  Tgu-Let-7-P2b1  Tur-Let-7  War-Let-7  Xbo-Let-7 
Node of Origin (locus) Gnathostomata
Node of Origin (family) Bilateria
Genome context
(rn6)		 chr17: 16418228-16418304 [+] UCSC Ensembl
Clustered miRNAs
(< 50kb from Let-7-P2b1)		 Let-7-P2a1 chr17: 16417865-16417936 [+] UCSC Ensembl
Let-7-P2b1 chr17: 16418228-16418304 [+] UCSC Ensembl
Let-7-P2c1 chr17: 16419993-16420067 [+] UCSC Ensembl
Precursor
(pre-Mir +30nt flank)
UUCCAGAAGAAAAAAAUUGCUCUAUCAGAGUGAGGUAGUAGAUUGUAUAGUUGUGGGGUAGUGAUUUUACCCUGUUUAGGAGAUAACUAUACAAUCUAUUGCCUUCCCUGAGGAGUAGACUUGCUGCAUUGUUUUAU
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Structure
        10           20        30        40        50        60        
UUCCAGAAGAAAAAAAU---|     A    AGU                     GUGGGGUAGUGAUUU 
                    UGCUCU UCAG   GAGGUAGUAGAUUGUAUAGUU               U
                    AUGAGG AGUC   UUCCGUUAUCUAACAUAUCAA               A
UAUUUUGUUACGUCGUUCAG^     -    CC-                     UAGAGGAUUUGUCCC 
     130       120        110        100        90        80        70
Deep sequencing
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3' NTU Yes
MotifsCNNC at 3p(+17), UGUG in loop
Tissue expression
-   +
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Mature sequence

Rno-Let-7-P2b1_5p
mirBase accessionMIMAT0000778
Sequence 
0- UGAGGUAGUAGAUUGUAUAGUU -22
Get sequence
Proposed targets microrna.org: MIMAT0000778
TargetScanVert: rno-let-7f-5p
miRDB: MIMAT0000778
Star sequence

Rno-Let-7-P2b1_3p*
mirBase accessionMIMAT0017089
Sequence 
56- CUAUACAAUCUAUUGCCUUCC -77
Get sequence
Proposed targets TargetScanVert: rno-let-7f-1-3p
miRDB: MIMAT0017089