Mir-10-P2c

MirGeneDB ID

Bta-Mir-10-P2c

Family name

MIR-10 (all species)

Seed

ACCCGUA

Species

Cow (Bos taurus)

MiRBase ID

bta-mir-99a

Paralogues

Bta-Mir-10-P1b-v1 Bta-Mir-10-P1b-v2 Bta-Mir-10-P1c-v1 Bta-Mir-10-P1c-v2 Bta-Mir-10-P2b Bta-Mir-10-P2d Bta-Mir-10-P3b Bta-Mir-10-P3c Bta-Mir-10-P3d

Orthologues

Aae-Mir-10-P2 Aca-Mir-10-P2c Adi-Mir-10 Aga-Mir-10-P2 Agr-Mir-10-P2 Ami-Mir-10-P2c Asp-Mir-10 Bfl-Mir-10-P2-v1 Bfl-Mir-10-P2-v2 Bge-Mir-10-P2 Bko-Mir-10-P2 Bla-Mir-10-P2-v1 Bla-Mir-10-P2-v2 Bpl-Mir-10-P2 Cbr-Mir-10-P2 Cel-Mir-10-P2 Cfa-Mir-10-P2c Cin-Mir-10-P2 Cja-Mir-10-P2c Cli-Mir-10-P2c Cmi-Mir-10-P2c Cpi-Mir-10-P2c Cpo-Mir-10-P2c Cte-Mir-10-P2 Dan-Mir-10-P2 Dgr-Mir-10-P2 Dlo-Mir-10-P2 Dma-Mir-10-P2 Dme-Mir-10-P2 Dmo-Mir-10-P2 Dno-Mir-10-P2c Dpu-Mir-10-P2 Dre-Mir-10-P2c1 Dre-Mir-10-P2c2 Dsi-Mir-10-P2 Dya-Mir-10-P2 Eba-Mir-10-P2 Eca-Mir-10-P2c Ete-Mir-10-P2c Gga-Mir-10-P2c Gja-Mir-10-P2c Gmo-Mir-10-P2c2 Gpa-Mir-10-P2 Gsp-Mir-10-P2 Hru-Mir-10-P2 Hsa-Mir-10-P2c Isc-Mir-10-P2 Laf-Mir-10-P2c Lan-Mir-10-P2 Lch-Mir-10-P2c Lgi-Mir-10-P2 Lhy-Mir-10-P2 Llo-Mir-10-P2 Loc-Mir-10-P2c Mal-Mir-10-P2c2 Mgi-Mir-10-P2 Mml-Mir-10-P2c Mmr-Mir-10-P2c Mmu-Mir-10-P2c Mom-Mir-10-P2 Mun-Mir-10-P2c Neu-Mir-10-P2c Npo-Mir-10-P2 Nve-Mir-10 Oan-Mir-10-P2c Obi-Mir-10-P2 Ocu-Mir-10-P2c Ofu-Mir-10-P2 Ovu-Mir-10-P2 Pab-Mir-10-P2c Pau-Mir-10-P2 Pbv-Mir-10-P2c Pca-Mir-10-P2 Pdu-Mir-10-P2 Pfl-Mir-10-P2 Ple-Mir-10-P2 Pmi-Mir-10-P2 Pve-Mir-10-P2 Rno-Mir-10-P2c Rph-Mir-10-P2 Sha-Mir-10-P2c Sko-Mir-10-P2 Snu-Mir-10-P2 Spt-Mir-10-P2c Sto-Mir-10-P2c Tca-Mir-10-P2 Tgu-Mir-10-P2c Tur-Mir-10-P2 Xbo-Mir-10-P2 Xbo-Mir-10-P2-as Xla-Mir-10-P2c3 Xla-Mir-10-P2c4 Xtr-Mir-10-P2c

Node of Origin (locus)

Gnathostomata

Node of Origin (family)

Eumetazoa

Genome context
(GCF_002263795.1_ARS-UCD1.2_BTA)

NC_037328.1: 20435353-20435411 [-] UCSC Ensembl

Clustered miRNAs
(< 50kb from Mir-10-P2c)

Mir-10-P3c NC_037328.1: 20385513-20385573 [-] UCSC Ensembl
Let-7-P1c NC_037328.1: 20434624-20434690 [-] UCSC Ensembl
Mir-10-P2c NC_037328.1: 20435353-20435411 [-] UCSC Ensembl

Precursor
(pre-Mir +30nt flank)

AGCCCACGUGAGACGUUGCCCAUUGGCAUAAACCCGUAGAUCCGAUCUUGUGGUGAAGUGGACCGCACAAGCUCGCUUCUAUGGGUCUGUGUCAGUGUGGUAAUCUGACAAAAUGCAAU

Get precursor sequence

Structure

        10         20         30        40        50         
AGCCCACGUGAGACGUU-   -|         A         UC   U      GUGAAG 
                  GCC CAUUGGCAUA ACCCGUAGA  CGA CUUGUG      \
                  UGG GUGACUGUGU UGGGUAUCU  GCU GAACAC      U
UAACGUAAAACAGUCUAA   U^         C         UC   C      GCCAGG 
       110       100        90        80        70        60

Deep sequencing

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Comment

Based on the 3' DcRNA reads in human (P2b) and platypus (P2c) it appears that this is a Group 2 miRNA.

3' NTU

Yes

Motifs

UG at 5p(-14), UGUG in loop

Tissue expression

Ad	Bo	Br	Ce	Co	Co	De	Fe	He	Hy	Ir	Ki	La	Lo	Mi	No	Op	Or	Pe	Re	Su	Te

Mature sequence

Bta-Mir-10-P2c_5p

mirBase accession

MIMAT0003537

Sequence

0- AACCCGUAGAUCCGAUCUUGUG -22

Get sequence

Proposed targets

TargetScanVert: bta-miR-99a-5p

Star sequence

Bta-Mir-10-P2c_3p*

mirBase accession

MIMAT0012533

Sequence

37- CAAGCUCGCUUCUAUGGGUCUG -59

Get sequence

Proposed targets

TargetScanVert: bta-miR-99a-3p