Mir-10-P2c1

MirGeneDB ID

Dre-Mir-10-P2c1

Family name

MIR-10 (all species)

Seed

ACCCGUA

Species

Zebrafish (Danio rerio)

MiRBase ID

dre-mir-99-1

Paralogues

Dre-Mir-10-P1b1-v1 Dre-Mir-10-P1b1-v2 Dre-Mir-10-P1b2-v1 Dre-Mir-10-P1b2-v2 Dre-Mir-10-P1c1-v1 Dre-Mir-10-P1c1-v2 Dre-Mir-10-P1c2-v1 Dre-Mir-10-P1c2-v2 Dre-Mir-10-P1d1-v1 Dre-Mir-10-P1d1-v2 Dre-Mir-10-P2c2 Dre-Mir-10-P2d1 Dre-Mir-10-P2d2 Dre-Mir-10-P3b1 Dre-Mir-10-P3b2 Dre-Mir-10-P3c1 Dre-Mir-10-P3c2 Dre-Mir-10-P3d1 Dre-Mir-10-P3d2

Orthologues

Aae-Mir-10-P2 Aca-Mir-10-P2c Adi-Mir-10 Aga-Mir-10-P2 Agr-Mir-10-P2 Ami-Mir-10-P2c Asp-Mir-10 Bfl-Mir-10-P2-v1 Bfl-Mir-10-P2-v2 Bge-Mir-10-P2 Bko-Mir-10-P2 Bla-Mir-10-P2-v1 Bla-Mir-10-P2-v2 Bpl-Mir-10-P2 Bta-Mir-10-P2c Cbr-Mir-10-P2 Cel-Mir-10-P2 Cfa-Mir-10-P2c Cin-Mir-10-P2 Cja-Mir-10-P2c Cli-Mir-10-P2c Cmi-Mir-10-P2c Cpi-Mir-10-P2c Cpo-Mir-10-P2c Cte-Mir-10-P2 Dan-Mir-10-P2 Dgr-Mir-10-P2 Dlo-Mir-10-P2 Dma-Mir-10-P2 Dme-Mir-10-P2 Dmo-Mir-10-P2 Dno-Mir-10-P2c Dpu-Mir-10-P2 Dsi-Mir-10-P2 Dya-Mir-10-P2 Eba-Mir-10-P2 Eca-Mir-10-P2c Ete-Mir-10-P2c Gga-Mir-10-P2c Gja-Mir-10-P2c Gpa-Mir-10-P2 Gsp-Mir-10-P2 Hru-Mir-10-P2 Hsa-Mir-10-P2c Isc-Mir-10-P2 Laf-Mir-10-P2c Lan-Mir-10-P2 Lch-Mir-10-P2c Lgi-Mir-10-P2 Lhy-Mir-10-P2 Llo-Mir-10-P2 Loc-Mir-10-P2c Mgi-Mir-10-P2 Mml-Mir-10-P2c Mmr-Mir-10-P2c Mmu-Mir-10-P2c Mom-Mir-10-P2 Mun-Mir-10-P2c Neu-Mir-10-P2c Npo-Mir-10-P2 Nve-Mir-10 Oan-Mir-10-P2c Obi-Mir-10-P2 Ocu-Mir-10-P2c Ofu-Mir-10-P2 Ovu-Mir-10-P2 Pab-Mir-10-P2c Pau-Mir-10-P2 Pbv-Mir-10-P2c Pca-Mir-10-P2 Pdu-Mir-10-P2 Pfl-Mir-10-P2 Ple-Mir-10-P2 Pmi-Mir-10-P2 Pve-Mir-10-P2 Rno-Mir-10-P2c Rph-Mir-10-P2 Sha-Mir-10-P2c Sko-Mir-10-P2 Snu-Mir-10-P2 Spt-Mir-10-P2c Sto-Mir-10-P2c Tca-Mir-10-P2 Tgu-Mir-10-P2c Tur-Mir-10-P2 Xbo-Mir-10-P2 Xbo-Mir-10-P2-as Xtr-Mir-10-P2c

Node of Origin (locus)

Clupeocephala

Node of Origin (family)

Eumetazoa

Genome context
(danRer11)

chr15: 29795596-29795654 [+] UCSC Ensembl

Clustered miRNAs
(< 50kb from Mir-10-P2c1)

Mir-10-P2c1 chr15: 29795596-29795654 [+] UCSC Ensembl
Let-7-P1c1 chr15: 29795845-29795911 [+] UCSC Ensembl
Mir-10-P3c1 chr15: 29800981-29801041 [+] UCSC Ensembl

Precursor
(pre-Mir +30nt flank)

CCAUGAUCAAAUGAGCAGCCACUUGUCAUUAACCCGUAGAUCCGAUCUUGUGAUAAGUUUGAUGGCACAAGCUCGAUUCUAUGGGUCUCUGUCUCUGUGGUAGAUAAUCGACCAACAUG

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Structure

        10         20         30        40        50         
CCAUGAUCAAAUGAGCA-     UUGU-| UUA         UC   U      AUAAGU 
                  GCCAC     CA   ACCCGUAGA  CGA CUUGUG      \
                  UGGUG     GU   UGGGUAUCU  GCU GAACAC      U
GUACAACCAGCUAAUAGA     UCUCU^ CUC         UA   C      GGUAGU 
       110       100        90        80        70        60

Deep sequencing

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Comment

Based on the 3' DcRNA reads in human (P2b) and platypus (P2c) it appears that this is a Group 2 miRNA.

3' NTU

Yes

Motifs

Tissue expression

Br	Br	Em	Ey	Gu	Gu	He	Li	Li	Ov	Te

Mature sequence

Dre-Mir-10-P2c1_5p

mirBase accession

MIMAT0001812

Sequence

0- AACCCGUAGAUCCGAUCUUGUG -22

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Proposed targets

TargetScanFish: dre-miR-99

Star sequence

Dre-Mir-10-P2c1_3p*

mirBase accession

None

Sequence

37- CAAGCUCGAUUCUAUGGGUCUC -59

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