Mir-10-P2c

MirGeneDB ID

Rno-Mir-10-P2c

Family name

MIR-10 (all species)

Seed

ACCCGUA

Species

Norway rat (Rattus norvegicus)

MiRBase ID

rno-mir-99a

Paralogues

Rno-Mir-10-P1b-v1 Rno-Mir-10-P1b-v2 Rno-Mir-10-P1c-v1 Rno-Mir-10-P1c-v2 Rno-Mir-10-P2b Rno-Mir-10-P2d Rno-Mir-10-P3b Rno-Mir-10-P3c Rno-Mir-10-P3d

Orthologues

Aae-Mir-10-P2 Aca-Mir-10-P2c Ami-Mir-10-P2c Bfl-Mir-10-P2-v1 Bfl-Mir-10-P2-v2 Bge-Mir-10-P2 Bla-Mir-10-P2-v1 Bla-Mir-10-P2-v2 Bpl-Mir-10-P2 Bta-Mir-10-P2c Cbr-Mir-10-P2 Cel-Mir-10-P2 Cfa-Mir-10-P2c Cgi-Mir-10-P2 Cin-Mir-10-P2 Cli-Mir-10-P2c Cmi-Mir-10-P2c Cpi-Mir-10-P2c Cpo-Mir-10-P2c Cte-Mir-10-P2 Dan-Mir-10-P2 Dma-Mir-10-P2 Dme-Mir-10-P2 Dmo-Mir-10-P2 Dno-Mir-10-P2c Dpu-Mir-10-P2 Dre-Mir-10-P2c1 Dre-Mir-10-P2c2 Dsi-Mir-10-P2 Dya-Mir-10-P2 Ete-Mir-10-P2c Gga-Mir-10-P2c Gja-Mir-10-P2c Gmo-Mir-10-P2c2 Hsa-Mir-10-P2c Isc-Mir-10-P2 Lan-Mir-10-P2 Lch-Mir-10-P2c Lgi-Mir-10-P2 Loc-Mir-10-P2c Mal-Mir-10-P2c2 Mml-Mir-10-P2c Mmu-Mir-10-P2c Mun-Mir-10-P2c Npo-Mir-10-P2 Nve-Mir-10 Oan-Mir-10-P2c Obi-Mir-10-P2 Ocu-Mir-10-P2c Ovu-Mir-10-P2 Pbv-Mir-10-P2c Pfl-Mir-10-P2 Pmi-Mir-10-P2 Sha-Mir-10-P2c Sko-Mir-10-P2 Spt-Mir-10-P2c Sto-Mir-10-P2c Tca-Mir-10-P2 Tgu-Mir-10-P2c Xbo-Mir-10-P2 Xbo-Mir-10-P2-as Xla-Mir-10-P2c3 Xla-Mir-10-P2c4 Xtr-Mir-10-P2c

Node of Origin (locus)

Gnathostomata

Node of Origin (family)

Eumetazoa

Genome context
(rn6)

chr11: 16052165-16052223 [+] UCSC Ensembl

Clustered miRNAs
(< 50kb from Mir-10-P2c)

Mir-10-P2c chr11: 16052165-16052223 [+] UCSC Ensembl
Let-7-P1c chr11: 16052888-16052954 [+] UCSC Ensembl
Mir-10-P3c chr11: 16097362-16097422 [+] UCSC Ensembl

Precursor
(pre-Mir +30nt flank)

AGUCCAUGUGGGAUGAUGCCCAUUGGCAUAAACCCGUAGAUCCGAUCUUGUGGUGAAGUGGACCGCACAAGCUCGUUUCUAUGGGUCUGUGGCAGUGUGGUAAUCUGACAGAGCACUAU

Get precursor sequence

Structure

        10         20         30        40        50         
AGUCCAUGUGGGAUGAU-   -|    G    A         UC   U      GUGAAG 
                  GCC CAUUG CAUA ACCCGUAGA  CGA CUUGUG      \
                  UGG GUGAC GUGU UGGGUAUCU  GCU GAACAC      U
UAUCACGAGACAGUCUAA   U^    G    C         UU   C      GCCAGG 
       110       100        90        80        70        60

Deep sequencing

Go to detailed chart

Comment

Based on the 3' moR reads in human (P2b) and platypus (P2c) it appears that this is a Group 2 miRNA.

3' NTU

Yes

Motifs

UG at 5p(-14), UGUG in loop

Tissue expression

Ad	Ad	Br	Br	Br	Ce	Ce	Ce	Ce	Co	Co	Co	Co	Dr	Dr	Du	Du	Du	Du	He	He	Hi	Hi	Il	Il	Je	Je	Ki	Ki	Ki	Ki	Li	Li	Li	Li	Me	Me	Mu	Mu	Mu	Mu	Mu	Mu	Mu	Mu	Ov	Pa	Pa	St	St	St	Te	Ut	Wh	Br	Fa	He	Ki	La	Li	Li	Lu	Mu	Pa	Sk	Sm	Sp	St	Te	Th

Mature sequence

Rno-Mir-10-P2c_5p

mirBase accession

MIMAT0000820

Sequence

0- AACCCGUAGAUCCGAUCUUGUG -22

Get sequence

Proposed targets

microrna.org: MIMAT0000820
TargetScanVert: rno-miR-99a-5p
miRDB: MIMAT0000820

Star sequence

Rno-Mir-10-P2c_3p*

mirBase accession

MIMAT0004724

Sequence

37- CAAGCUCGUUUCUAUGGGUCUG -59

Get sequence

Proposed targets

microrna.org: MIMAT0004724
TargetScanVert: rno-miR-99a-3p
miRDB: MIMAT0004724