Mir-10-P2c

MirGeneDB ID

Cfa-Mir-10-P2c

Family name

MIR-10 (all species)

Seed

ACCCGUA

Species

Dog (Canis familiaris)

MiRBase ID

cfa-mir-99a-1

Paralogues

Cfa-Mir-10-P1b-v1 Cfa-Mir-10-P1b-v2 Cfa-Mir-10-P1c-v1 Cfa-Mir-10-P1c-v2 Cfa-Mir-10-P2b Cfa-Mir-10-P2d Cfa-Mir-10-P3b Cfa-Mir-10-P3c Cfa-Mir-10-P3d

Orthologues

Aae-Mir-10-P2 Aca-Mir-10-P2c Adi-Mir-10 Aga-Mir-10-P2 Agr-Mir-10-P2 Ami-Mir-10-P2c Asp-Mir-10 Bfl-Mir-10-P2-v1 Bfl-Mir-10-P2-v2 Bge-Mir-10-P2 Bko-Mir-10-P2 Bla-Mir-10-P2-v1 Bla-Mir-10-P2-v2 Bpl-Mir-10-P2 Bta-Mir-10-P2c Cbr-Mir-10-P2 Cel-Mir-10-P2 Cin-Mir-10-P2 Cja-Mir-10-P2c Cli-Mir-10-P2c Cmi-Mir-10-P2c Cpi-Mir-10-P2c Cpo-Mir-10-P2c Cte-Mir-10-P2 Dan-Mir-10-P2 Dgr-Mir-10-P2 Dlo-Mir-10-P2 Dma-Mir-10-P2 Dme-Mir-10-P2 Dmo-Mir-10-P2 Dno-Mir-10-P2c Dpu-Mir-10-P2 Dre-Mir-10-P2c1 Dre-Mir-10-P2c2 Dsi-Mir-10-P2 Dya-Mir-10-P2 Eba-Mir-10-P2 Eca-Mir-10-P2c Ete-Mir-10-P2c Gga-Mir-10-P2c Gja-Mir-10-P2c Gmo-Mir-10-P2c2 Gpa-Mir-10-P2 Gsp-Mir-10-P2 Hru-Mir-10-P2 Hsa-Mir-10-P2c Isc-Mir-10-P2 Laf-Mir-10-P2c Lan-Mir-10-P2 Lch-Mir-10-P2c Lgi-Mir-10-P2 Lhy-Mir-10-P2 Llo-Mir-10-P2 Loc-Mir-10-P2c Mal-Mir-10-P2c2 Mgi-Mir-10-P2 Mml-Mir-10-P2c Mmr-Mir-10-P2c Mmu-Mir-10-P2c Mom-Mir-10-P2 Mun-Mir-10-P2c Neu-Mir-10-P2c Npo-Mir-10-P2 Nve-Mir-10 Oan-Mir-10-P2c Obi-Mir-10-P2 Ocu-Mir-10-P2c Ofu-Mir-10-P2 Ovu-Mir-10-P2 Pab-Mir-10-P2c Pau-Mir-10-P2 Pbv-Mir-10-P2c Pca-Mir-10-P2 Pdu-Mir-10-P2 Pfl-Mir-10-P2 Ple-Mir-10-P2 Pmi-Mir-10-P2 Pve-Mir-10-P2 Rno-Mir-10-P2c Rph-Mir-10-P2 Sha-Mir-10-P2c Sko-Mir-10-P2 Snu-Mir-10-P2 Spt-Mir-10-P2c Sto-Mir-10-P2c Tca-Mir-10-P2 Tgu-Mir-10-P2c Tur-Mir-10-P2 Xbo-Mir-10-P2 Xbo-Mir-10-P2-as Xla-Mir-10-P2c3 Xla-Mir-10-P2c4 Xtr-Mir-10-P2c

Node of Origin (locus)

Gnathostomata

Node of Origin (family)

Eumetazoa

Genome context
(canFam3_add)

chr31: 13258782-13258840 [+] UCSC Ensembl

Clustered miRNAs
(< 50kb from Mir-10-P2c)

Mir-10-P2c chr31: 13258782-13258840 [+] UCSC Ensembl
Let-7-P1c chr31: 13259522-13259588 [+] UCSC Ensembl
Mir-10-P3c chr31: 13304980-13305040 [+] UCSC Ensembl

Precursor
(pre-Mir +30nt flank)

AGCCCAAGUGAGAUGUUGCCCAUUGGCAUAAACCCGUAGAUCCGAUCUUGUGGUGAAGUGGACGGCACAAGCUCGCUUCUAUGGGUCUGUGUCAGUGUGGUCAUCUAACAAAAUGCUAU

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Structure

        10         20         30        40        50         
AGCCCAAGUGAGAUGUU-   -|         A         UC   U      GUGAAG 
                  GCC CAUUGGCAUA ACCCGUAGA  CGA CUUGUG      \
                  UGG GUGACUGUGU UGGGUAUCU  GCU GAACAC      U
UAUCGUAAAACAAUCUAC   U^         C         UC   C      GGCAGG 
       110       100        90        80        70        60

Deep sequencing

Go to detailed chart

Comment

Based on the 3' DcRNA reads in human (P2b) and platypus (P2c) it appears that this is a Group 2 miRNA.

3' NTU

Yes

Motifs

UG at 5p(-14), UGUG in loop

Tissue expression

An	An	An	Bl	Ce	Co	He	Hi	Hi	Hy	Ki	Ki	Li	Lu	Ov	Sk	Te	Te

Mature sequence

Cfa-Mir-10-P2c_5p

mirBase accession

MIMAT0006668

Sequence

0- AACCCGUAGAUCCGAUCUUGUG -22

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Proposed targets

TargetScanVert: cfa-miR-99a
miRDB: MIMAT0006668

Star sequence

Cfa-Mir-10-P2c_3p*

mirBase accession

None

Sequence

37- CAAGCUCGCUUCUAUGGGUCUG -59

Get sequence