Let-7-P1d

MirGeneDB ID

Mmu-Let-7-P1d

Family name

LET-7 (all species)

Seed

GAGGUAG

Species

House mouse (Mus musculus)

MiRBase ID

mmu-let-7a-2

Paralogues

Mmu-Let-7-P1b Mmu-Let-7-P1c Mmu-Let-7-P2a1 Mmu-Let-7-P2a2 Mmu-Let-7-P2a3 Mmu-Let-7-P2b1 Mmu-Let-7-P2b2 Mmu-Let-7-P2b3 Mmu-Let-7-P2c1 Mmu-Let-7-P2c2 Mmu-Let-7-P2c3

Orthologues

Aae-Let-7 Aca-Let-7-P1d Aga-Let-7 Agr-Let-7 Ami-Let-7-P1d Bge-Let-7 Bko-Let-7 Bpl-Let-7 Bta-Let-7-P1d Cfa-Let-7-P1d Cin-Let-7-P1 Cja-Let-7-P1d Cli-Let-7-P1d Cmi-Let-7-P1d Cpi-Let-7-P1d Cpo-Let-7-P1d Cte-Let-7 Dan-Let-7 Dlo-Let-7 Dma-Let-7 Dme-Let-7 Dmo-Let-7 Dno-Let-7-P1d Dpu-Let-7 Dre-Let-7-P1d1 Dre-Let-7-P1d2 Dsi-Let-7 Dya-Let-7 Eba-Let-7 Eca-Let-7-P1d Egr-Let-7 Esc-Let-7 Ete-Let-7-P1d Gga-Let-7-P1d Gja-Let-7-P1d Gmo-Let-7-P1d1 Gmo-Let-7-P1d2 Gpa-Let-7 Gsa-Let-7 Gsp-Let-7 Hme-Let-7 Hmi-Let-7 Hru-Let-7 Hsa-Let-7-P1d Isc-Let-7 Laf-Let-7-P1d Lan-Let-7 Lch-Let-7-P1d Lgi-Let-7 Lhy-Let-7 Llo-Let-7 Loc-Let-7-P1d Mal-Let-7-P1d1 Mal-Let-7-P1d2 Mdo-Let-7-P1d Mgi-Let-7 Mml-Let-7-P1d Mmr-Let-7-P1d Mom-Let-7 Mun-Let-7-P1d Neu-Let-7-P1d Npo-Let-7 Oan-Let-7-P1d Obi-Let-7 Ocu-Let-7-P1d Ofu-Let-7 Ovu-Let-7 Pab-Let-7-P1d Pau-Let-7 Pbv-Let-7-P1d Pca-Let-7 Pcr-Let-7 Pdu-Let-7 Pfl-Let-7 Ple-Let-7 Pmi-Let-7 Pve-Let-7 Rno-Let-7-P1d Rph-Let-7 Sha-Let-7-P1d Sko-Let-7 Sma-Let-7 Sne-Let-7 Snu-Let-7 Spt-Let-7-P1d Spu-Let-7 Sro-Let-7 Sto-Let-7-P1d Tca-Let-7 Tgu-Let-7-P1d Tni-Let-7-P1d1 Tni-Let-7-P1d2 Tur-Let-7 War-Let-7 Xbo-Let-7

Node of Origin (locus)

Gnathostomata

Node of Origin (family)

Bilateria

Genome context
(mm10)

chr9: 41536732-41536798 [+] UCSC Ensembl

Clustered miRNAs
(< 50kb from Let-7-P1d)

Mir-10-P2d chr9: 41531437-41531493 [+] UCSC Ensembl
Let-7-P1d chr9: 41536732-41536798 [+] UCSC Ensembl
Mir-10-P3d chr9: 41581940-41582001 [+] UCSC Ensembl

Precursor
(pre-Mir +30nt flank)

UCCAGCCAUUGUGACUGCAUGUUCCCAGGUUGAGGUAGUAGGUUGUAUAGUUUAGAGUUACAUCAAGGGAGAUAACUGUACAGCCUCCUAGCUUUCCUUGGGACUUGCACAAAGCAACAUGGCAAGA

Get precursor sequence

Structure

        10        20           30        40        50        60   
UCCAGCCAUUGUGACUGCA   ---|      UU   G   U             UAGAGUUACA 
                   UGU   UCCCAGG  GAG UAG AGGUUGUAUAGUU          \
                   ACG   AGGGUUC  UUC AUC UCCGACAUGUCAA          U
AGAACGGUACAACGAAAC-   UUC^      CU   G   C             UAGAGGGAAC 
     120       110        100        90        80        70

Deep sequencing

Go to detailed chart

3' NTU

Motifs

CNNC at 3p(+17)

Tissue expression

Br	Br	Ce	Ce	Em	Em	He	Ki	Li	Lu	Ov	Pa	Sk	Sp	Te

Mature sequence

Mmu-Let-7-P1d_5p

mirBase accession

MIMAT0000521

Sequence

0- UGAGGUAGUAGGUUGUAUAGUU -22

Get sequence

Proposed targets

microrna.org: MIMAT0000521
TargetScanVert: mmu-let-7a-5p
miRDB: MIMAT0000521

Star sequence

Mmu-Let-7-P1d_3p*

mirBase accession

MIMAT0017015

Sequence

45- CUGUACAGCCUCCUAGCUUUCC -67

Get sequence

Proposed targets

TargetScanVert: mmu-let-7a-2-3p
miRDB: MIMAT0017015